ChemicalBook > CAS DataBase List > D-Glucose monohydrate

D-Glucose monohydrate

Product Name
D-Glucose monohydrate
CAS No.
5996-10-1
Chemical Name
D-Glucose monohydrate
Synonyms
Glucose;Dextrose monohydrate;Dextrose 1-hydrate;Corn sugar;DEXTROSE USP MONOHYDRATE;C6H12O6.H2O;DEXTROSE 1HYD PWD;One water glucose;Dextrose, granular;D-Glucose monohydrate
CBNumber
CB3211706
Molecular Formula
C6H14O7
Formula Weight
198.17
MOL File
5996-10-1.mol
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D-Glucose monohydrate Property

Melting point:
83°C
Density 
1.54
solubility 
Freely soluble in water, sparingly soluble in ethanol (96 per cent).
form 
Solid
color 
Colorless crystals
Odor
Odorless
PH Range
5.9
Water Solubility 
1 g/1.1 ml water @ 250C
CAS DataBase Reference
5996-10-1(CAS DataBase Reference)
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Safety

HS Code 
17023051
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
MG05194
Product name
D-Glucose - monohydrate
Packaging
5kg
Price
$47.3
Updated
2021/12/16
Biosynth Carbosynth
Product number
MG05194
Product name
D-Glucose - monohydrate
Packaging
10Kg
Price
$68.3
Updated
2021/12/16
Biosynth Carbosynth
Product number
MG05194
Product name
D-Glucose - monohydrate
Packaging
25kg
Price
$131.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
MG05194
Product name
D-Glucose - monohydrate
Packaging
50kg
Price
$235
Updated
2021/12/16
Biosynth Carbosynth
Product number
MG05194
Product name
D-Glucose - monohydrate
Packaging
100kg
Price
$400
Updated
2021/12/16
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D-Glucose monohydrate Chemical Properties,Usage,Production

Chemical Properties

Dextrose occurs as odorless, sweet-tasting, colorless crystals or as a white crystalline or granular powder. The JP XV describes dextrose as dextrose anhydrous; the PhEur 6.3 specifies dextrose as either dextrose anhydrous or dextrose monohydrate; and the USP 32 specifies dextrose as dextrose monohydrate.

Chemical Properties

D-Glucose monohydrate is white or almost white, crystalline powder.

Uses

Replenisher (fluid and nutrient).

Definition

A monosaccharide occurring widely in nature as D-glucose. It occurs as glucose units in sucrose, starch, and cellulose. It is important to metabolism because it participates in energy-storage and energy-release systems.

Production Methods

Dextrose, a monosaccharide sugar, occurs widely in plants and is manufactured on a large scale by the acid or enzymatic hydrolysis of starch, usually maize (corn) starch. Below 50°C a-D-dextrose monohydrate is the stable crystalline form produced; above 50°C the anhydrous form is obtained; and at still higher temperatures b-D-dextrose is formed, which has a melting point of 148–155°C.

brand name

Cartose (Sterling Winthrop) Dextrose.

Pharmaceutical Applications

Dextrose is widely used in solutions to adjust tonicity and as a sweetening agent.Dextrose is also used as a wet granulation diluent and binder, primarily in chewable tablets.Although dextrose is comparable as a tablet diluent to lactose, tablets produced with dextrose monohydrate require more lubrication, are less friable, and have a tendency to harden. The mildly reducing properties of dextrose may be used when tableting to improve the stability of active materials that are sensitive to oxidation.
Dextrose is also used therapeutically and is the preferred source of carbohydrate in parenteral nutrition regimens.

Agricultural Uses

Glucose is a monosaccharide sugar found in honey and fruits. It is the primary product of plant photosynthesis, which is optically active and dextrorotatory.
Glucose and its derivatives are critically important in the energy metabolism of living organisms. It is transported around the animal body through blood, and by lymph and cerebrospinal fluid, to cells where the energy is released during glycolysis.
Fructose, the stereoisomer of glucose, occurs in green plants, fruits and honey. It is sweeter than sucrose.
Yeasts readily ferment glucose to produce ethyl alcohol and carbon dioxide. It is also metabolized by bacteria into acetic and butyric acids, lactic acid, butyl alcohol, acetone, hydrogen, carbon dioxide and many other compounds.
Plants and animals convert complex carbohydrates (like starch and glycogen) into glucose to meet their energy needs. Glucose is produced commercially by hydrolysing corn starch with dilute mineral acid. Commercial glucose is mostly used in the manufacture of confections and in the canning industry.

Safety

D-Glucose monohydrate is rapidly absorbed from the gastrointestinal tract. It is metabolized to carbondioxide and water with therelease ofenergy.
Concentrated D-Glucose monohydrate solutions given by mouth may cause nausea and vomiting. D-Glucose monohydrate solutions of concentration greater than 5% w/v are hyperosmotic and are liable to cause local vein irritation following intravenous administration. Thrombophlebitis has been observed following the intravenous infusion of isoosmotic D-Glucose monohydrate solution with low pH, probably owing to the presence of degradation products formed by overheating during sterilization. The incidence of phlebitis may be reduced by adding sufficient sodium bicarbonate to raise the pH of the infusion above pH 7.
LD50 (mouse, IV): 9g/kg
LD50 (rat, oral): 25.8g/kg

Physiological effects

Dextrose Monohydrate is the monohydrate form of D-glucose, it restore blood glucose levels, provide calories, may aid in minimizing liver glycogen depletion and exerts a protein-sparing action.Dextrose Monohydratealso plays a role in the production of proteins and in lipid metabolism.

storage

D-Glucose monohydrate has good stability under dry storage conditions. Aqueous solutions may be sterilized by autoclaving. However, excessive heating can cause a reduction in pH and caramelization of solutions.
Thebulkmaterialshouldbestoredinawell-closedcontainerina cool, dry place.

Incompatibilities

Dextrose solutions are incompatible with a number of drugs such as cyanocobalamin, kanamycin sulfate, novobiocin sodium, and warfarin sodium. Erythromycin gluceptate isunstable indextrose solutions at a pH less than 5.05. Decomposition of B-complex vitamins may occur if they are warmed with dextrose.
In the aldehyde form, dextrose can react with amines, amides, amino acids, peptides, and proteins. Brown coloration and decomposition occur with strong alkalis.
Dextrose may cause browning of tablets containing amines (Maillard reaction).

Regulatory Status

Included in the FDA Inactive Ingredients Database (capsules; inhalations; IM, IV, and SC injections; tablets, oral solutions, and syrups). Included in nonparenteral and parenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

D-Glucose monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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D-Glucose monohydrate Suppliers

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View Lastest Price from D-Glucose monohydrate manufacturers

Hebei Dangtong Import and export Co LTD
Product
D-Glucose monohydrate 5996-10-1
Price
US $655.00-640.00/Tons
Min. Order
1Tons
Purity
99%
Supply Ability
100Tons
Release date
2023-03-03
Hebei Yime New Material Technology Co., Ltd.
Product
Dextrose Monohydrate 5996-10-1
Price
US $20.00-15.00/kg
Min. Order
1000kg
Purity
99%
Supply Ability
5000kg/week
Release date
2023-11-07
Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
D-Glucose monohydrate 5996-10-1
Price
US $10.00/kg
Min. Order
1kg
Purity
99.7%
Supply Ability
200000kg
Release date
2024-04-26

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