ChemicalBook > CAS DataBase List > 5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE

5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE

Product Name
5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE
CAS No.
28480-70-8
Chemical Name
5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE
Synonyms
2-ACETYL-4-CHLORO-5-METHYLPHENOL;4-ACETYL-2-CHLORO-5-HYDROXYTOLUENE;5-CHLORO-2-HYDROXY-4-METHYLACETOPHENONE;5'-Cloro-2'-Hydroxy-4'-Methylacetophenone;5'-Chooro-2'-Hydroxy-4'-Methylacetophenone;5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE;5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE;1-(5-CHLORO-2-HYDROXY-4-METHYLPHENYL)ETHANONE;5'-Chloro-2'-hydroxy-4'-methylacetophenone >5'-Chloro-2'-hydroxy-4'-methylacetophenone 98%
CBNumber
CB3212213
Molecular Formula
C9H9ClO2
Formula Weight
184.62
MOL File
28480-70-8.mol
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5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE Property

Melting point:
70-73 °C(lit.)
Boiling point:
137 °C / 15mmHg
Density 
1.250±0.06 g/cm3(Predicted)
form 
powder to crystal
pka
9.84±0.23(Predicted)
color 
White to Light yellow
CAS DataBase Reference
28480-70-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
2914.50.3000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
415758
Product name
5′-Chloro-2′-hydroxy-4′-methylacetophenone
Purity
98%
Packaging
5g
Price
$42.6
Updated
2023/06/20
TCI Chemical
Product number
C1629
Product name
5'-Chloro-2'-hydroxy-4'-methylacetophenone
Purity
>95.0%(GC)
Packaging
5g
Price
$20
Updated
2024/03/01
TCI Chemical
Product number
C1629
Product name
5'-Chloro-2'-hydroxy-4'-methylacetophenone
Purity
>95.0%(GC)
Packaging
25g
Price
$60
Updated
2024/03/01
TRC
Product number
C585845
Product name
5''-Chloro-2''-hydroxy-4''-methylacetophenone
Packaging
100mg
Price
$60
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC53830
Product name
5'-Chloro-2'-hydroxy-4'-methylacetophenone
Packaging
25g
Price
$40
Updated
2021/12/16
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5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE Chemical Properties,Usage,Production

Uses

5′-Chloro-2′-hydroxy-4′-methylacetophenone (5-chloro-2-hydroxy-4-methylacetophenone) may be used in the preparation of the following:

  • chalcones, required for the synthesis of novel pyrazoline derivatives
  • 5′-chloro-2′-hydroxy-4′-methyl-3-(2′′-thienyl)acrylophenone
  • 6-chloro-3-hydroxy-7-methyl-2-(2-thienyl)-4H-chromen-4-one, a complexing agent used for the spectrophotometric determination of vanadium(V)

Preparation

Preparation by reaction of acetic acid on 4-chloro-3- methylphenol with boron trifluoride at 70–100° (80–85%).

General Description

5′-chloro-2′-hydroxy-4′-methylacetophenone (5-Chloro-2-hydroxy-4-methylacetophenone) is a hydroxylated aromatic acetophenone. Its iodination by pyridinium iodochloride has been reported to afford 5-chloro-2-hydroxy-3-iodo-4-methylacetophenone.

5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE Preparation Products And Raw materials

Raw materials

Preparation Products

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5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE Suppliers

Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
15229059051
Email
1027@dideu.com
Country
China
ProdList
10003
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80

28480-70-8, 5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONERelated Search:


  • 5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE
  • 5-CHLORO-2-HYDROXY-4-METHYLACETOPHENONE
  • 4-ACETYL-2-CHLORO-5-HYDROXYTOLUENE
  • 1-(5-CHLORO-2-HYDROXY-4-METHYLPHENYL)ETHANONE
  • 2-ACETYL-4-CHLORO-5-METHYLPHENOL
  • 5'-Chooro-2'-Hydroxy-4'-Methylacetophenone
  • JRH-01005, 1-(5-Chloro-2-hydroxy-4-methylphenyl)ethanone, 97%
  • 4-Acetyl-2-chloro-5-hydroxytoluene 2-Acetyl-4-chloro-5-methylphenol
  • 5'-Chloro-2'-hydroxy-4'-methylacetophenone 98%
  • 5'-Chloro-2'-hydroxy-4'-methylacetophenone &gt
  • Ethanone, 1-(5-chloro-2-hydroxy-4-methylphenyl)-
  • 5'-Cloro-2'-Hydroxy-4'-Methylacetophenone
  • 5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE
  • 28480-70-8
  • ClC6H2OHCH3COCH3
  • C9
  • Carbonyl Compounds
  • Building Blocks
  • Organic Building Blocks
  • Ketones
  • Ketones
  • Aromatic Acetophenones & Derivatives (substituted)
  • C9
  • Carbonyl Compounds