Chloromethyl isobutyrate
- Product Name
- Chloromethyl isobutyrate
- CAS No.
- 61644-18-6
- Chemical Name
- Chloromethyl isobutyrate
- Synonyms
- Chloromethyl isobutyrate;(Isobutyryloxy)methyl chloride;Chloromethyl 2-methylpropionate;Chloromethyl 2-methylpropanoate;Propanoicacid, 2-methyl-, chloromethyl ester
- CBNumber
- CB32123320
- Molecular Formula
- C5H9ClO2
- Formula Weight
- 136.58
- MOL File
- 61644-18-6.mol
Chloromethyl isobutyrate Property
- Boiling point:
- 124.6±13.0 °C(Predicted)
- Density
- 1.081±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Chloroform (Sparingly), Methanol (Slightly)
- form
- Oil
- color
- Colourless
- InChI
- InChI=1S/C5H9ClO2/c1-4(2)5(7)8-3-6/h4H,3H2,1-2H3
- InChIKey
- ILUWVORABZTBIU-UHFFFAOYSA-N
- SMILES
- C(OCCl)(=O)C(C)C
Safety
- RIDADR
- UN2920
- HazardClass
- 8, 3
- HS Code
- 2915907098
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H318Causes serious eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- C381950
- Product name
- ChloromethylIsobutyrate
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FC160496
- Product name
- Chloromethyl Isobutyrate
- Packaging
- 5G
- Price
- $70
- Updated
- 2021/12/16
- Product number
- FC160496
- Product name
- Chloromethyl Isobutyrate
- Packaging
- 10g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FC160496
- Product name
- Chloromethyl Isobutyrate
- Packaging
- 25g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- FC160496
- Product name
- Chloromethyl Isobutyrate
- Packaging
- 50g
- Price
- $250
- Updated
- 2021/12/16
Chloromethyl isobutyrate Chemical Properties,Usage,Production
Synthesis
49715-04-0
79-31-2
61644-18-6
Step A: Synthesis of chloromethyl isobutyrate To a solution of isobutyric acid (0.600 mL, 6.47 mmol) in dichloromethane (DCM, 6 mL) was added sodium bicarbonate (2092 mg, 24.91 mmol), tetrabutylammonium hydrogensulfate (220 mg, 0.65 mmol), and water (6 mL) in that order. Chloromethyl chloroformate (0.767 mL, 7.44 mmol) was added slowly at room temperature with rapid stirring. After addition, the reaction mixture was continued to stir at room temperature overnight. Upon completion of the reaction, the reaction mixture was diluted with dichloromethane (10 mL) and subsequently washed with water (2 x 10 mL). The organic phase was dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated to afford the crude chloromethyl isobutyrate (746 mg, 84% yield). The product was used directly in the next step of the reaction without further purification. 1H NMR (500 MHz, CDCl3) δ ppm: 1.17 (m, 6H), 2.62 (m, 1H), 5.72 (s, 2H).
References
[1] Patent: WO2015/67923, 2015, A1. Location in patent: Paragraph 00072; 00073; 00074
[2] Patent: US2018/37550, 2018, A1. Location in patent: Paragraph 0081-0083
[3] Patent: WO2014/4884, 2014, A1. Location in patent: Paragraph 00310-00311; 00322
Chloromethyl isobutyrate Preparation Products And Raw materials
Raw materials
Preparation Products
Chloromethyl isobutyrate Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from Chloromethyl isobutyrate manufacturers
- Product
- Chloromethyl isobutyrate 61644-18-6
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-09