7-Octynoic acid

Product Name: 7-Octynoic acid
CAS No.: 10297-09-3
Chemical Name: 7-Octynoic acid
Synonyms: oct-7-ynoic acid;7-Octynoic acid;WJBHDZBQZOMDFF-UHFFFAOYSA-N
CBNumber: CB32153859
Molecular Formula: C8H12O2
Formula Weight: 140.18
MOL File: 10297-09-3.mol

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7-Octynoic acid Property

Melting point:: 19°C
Boiling point:: 290.64°C (rough estimate)
Density: 1.0450 (rough estimate)
refractive index: 1.4502
solubility: DMSO: 150 mg/mL (1070.05 mM)
form: Liquid
pka: 4.74±0.10(Predicted)
color: Colorless to light pink
Water Solubility: Water: 5 mg/mL (35.67 mM)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B508923
Product name: Oct-7-ynoicAcid
Packaging: 100mg
Price: $330
Updated: 2021/12/16

AK Scientific

Product number: 2646BB
Product name: 7-Octynoicacid
Packaging: 500mg
Price: $988
Updated: 2021/12/16

Ambeed

Product number: A393928
Product name: Oct-7-ynoicacid
Purity: 97%
Packaging: 1g
Price: $333
Updated: 2021/12/16

Ambeed

Product number: A393928
Product name: Oct-7-ynoicacid
Purity: 97%
Packaging: 100mg
Price: $95
Updated: 2021/12/16

Ambeed

Product number: A393928
Product name: Oct-7-ynoicacid
Purity: 97%
Packaging: 250mg
Price: $137
Updated: 2021/12/16

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7-Octynoic acid Chemical Properties,Usage,Production

Uses

7-Octynoic acid (compound 42) is a PROTAC linker and can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. 7-Octynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Definition

ChEBI: 7-octynoic acid is a medium-chain fatty acid.

IC 50

Alkyl-Chain

References

[1] Bai L, et al. A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer Cell. 2019 Nov 11;36(5):498-511.e17. DOI:10.1016/j.ccell.2019.10.002

7-Octynoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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7-Octynoic acid Suppliers

China 55 India 2 United States 5 Global 62

PharmaBlock Sciences (Nanjing),Inc.

Tel: 025-86918202 4000255188
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Adamas Reagent, Ltd.

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Bide Pharmatech Ltd.

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Shanghai Synchem Pharma Co., ltd

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Email: synchempharma@aliyun.com
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SPIRO PHARMA

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Shanghai YuanYe Biotechnology Co., Ltd.

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Panjin Infinity Scientific CO. LTD

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Beijing Jin Ming Biotechnology Co., Ltd.

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Shanghai Yihe Biological Technology Co., Ltd.

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Aikon International Limited

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10297-09-3, 7-Octynoic acidRelated Search:

7-Octynoic acid

oct-7-ynoic acid

WJBHDZBQZOMDFF-UHFFFAOYSA-N

10297-09-3