1-Methoxy-9H-carbazole-3-carbaldehyde
- Product Name
- 1-Methoxy-9H-carbazole-3-carbaldehyde
- CAS No.
- 723-97-7
- Chemical Name
- 1-Methoxy-9H-carbazole-3-carbaldehyde
- Synonyms
- Murrayanine;1-Methoxy-9H-carbazole-3-carbaldehyde;9H-Carbazole-3-carboxaldehyde, 1-methoxy-
- CBNumber
- CB32223213
- Molecular Formula
- C14H11NO2
- Formula Weight
- 225.24
- MOL File
- 723-97-7.mol
1-Methoxy-9H-carbazole-3-carbaldehyde Property
- Melting point:
- 168°C
- Boiling point:
- 466.4±25.0 °C(Predicted)
- Density
- 1.312±0.06 g/cm3(Predicted)
- pka
- 16.49±0.30(Predicted)
1-Methoxy-9H-carbazole-3-carbaldehyde Chemical Properties,Usage,Production
Description
This simple carbazole alkaloid is found in the stem bark of Mu"aya koenigii Spreng. It is best purified by sublimation of the crude base when it yields colour_x0002_less crystals. The ultraviolet spectrum in ethanol has absorption maxima at 238, 247,274,289 and 335 mJJ.. The structure has been shown to be 3-formyl-lmethoxycarbazole by spectroscopic methods and synthesis. It yields an oxime, m.p. l55-6°C; a picrate, m.p. 198-2000 C and the 2:4-dinitrophenylhydrazone, m.p. > 300°C. The N-methyl derivative forms colourless needles from C6H6- light petroleum, m.p. l48-9°C. When subjected to Wolff-Kishner reduction, the alkaline phase yields l-hydroxy-3-methyl-carbazole.
Uses
Murrayanine is a carbazole alkaloid. Murrayanine suppresses the proliferation and metastasis of human breast cancer cells via induction of apoptosis and inhibition of RANK/RANKL signaling pathway.
Definition
ChEBI: A natural product found in Clausena harmandiana.
References
Chakraborty, Barman, Bose., Tetrahedron, 21, 681 (1965)
Synthesis:
Crum, Sprague., Chern. Cornrnun., 417 (1966)
Chakraborty, Chowdhury., J. Org. Chern., 33, 1265 (1968)
1-Methoxy-9H-carbazole-3-carbaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
1-Methoxy-9H-carbazole-3-carbaldehyde Suppliers
- Tel
- 0871-65217109 13211707573;
- Fax
- 0871-65215563
- y.liu@mail.biobiopha.com
- Country
- China
- ProdList
- 5653
- Advantage
- 65
- Tel
- 028-81700200 18116577057
- Fax
- 028-81705658
- 3003855609@qq.com
- Country
- China
- ProdList
- 7887
- Advantage
- 56
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 27313
- Advantage
- 60
- Tel
- +1-631-485-4226
- Fax
- 1-631-614-7828
- inquiry@bocsci.com
- Country
- United States
- ProdList
- 19553
- Advantage
- 58
- Tel
- 021-57763112 13585886131
- 3004987436@qq.com
- Country
- China
- ProdList
- 9693
- Advantage
- 58
- Tel
- 18018507602 15900573766
- 394643792@qq.com
- Country
- China
- ProdList
- 3025
- Advantage
- 58
- Tel
- 400-8087372 13161114455
- puxi_sale@qq.com
- Country
- China
- ProdList
- 4990
- Advantage
- 58
- Tel
- 021-38218169 13341702378
- 190129269@qq.com
- Country
- China
- ProdList
- 9122
- Advantage
- 58
- Tel
- 025-85560043 15850508050
- Fax
- 025-85563444
- cindy.huang@synzest.com
- Country
- China
- ProdList
- 12005
- Advantage
- 58
- Tel
- 18162791556
- 3152548389@qq.com
- Country
- China
- ProdList
- 4351
- Advantage
- 58