Phophorylating Reagent
ChemicalBook > CAS DataBase List > DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE

DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE

Phophorylating Reagent
Product Name
DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE
CAS No.
126429-21-8
Chemical Name
DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE
Synonyms
DIALLYL DIISOPROPYLPHOSPHORAMIDITE;Diallyloxy(diisopropylamino)phosphine;DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE;N-bis(prop-2-enoxy)phosphanyl-N-propan-2-ylpropan-2-amine;N,N-Bis(1-methylethyl)phosphoramidous acid di-2-propenyl ester;Phosphoramidous acid, N,N-bis(1-methylethyl)-, di-2-propen-1-yl ester
CBNumber
CB3224528
Molecular Formula
C12H24NO2P
Formula Weight
245.3
MOL File
126429-21-8.mol
More
Less

DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE Property

Boiling point:
130 °C(lit.)
Density 
0.928 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.456(lit.)
Flash point:
90 °F
storage temp. 
2-8°C
pka
4.96±0.70(Predicted)
BRN 
4383514
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
10-36/37/38
Safety Statements 
26-36
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
1-10
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
439606
Product name
Diallyl N,N-diisopropylphosphoramidite
Packaging
1g
Price
$188.4
Updated
2024/03/01
TRC
Product number
D416130
Product name
Diallyl N,N-diisopropylphosphoramidite
Packaging
100mg
Price
$140
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0156822
Product name
DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE
Purity
95.00%
Packaging
1G
Price
$672.53
Updated
2021/12/16
More
Less

DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE Chemical Properties,Usage,Production

Phophorylating Reagent

Diallyl N,N-diisopropylphosphoramidite was employed as a phophorylating reagent. It can be used for reactions involved in phosphitylation of alcohols, deallylation for the synthesis of nucleoside phosphoramidite, posphitylation and stereoselective pudovik rearrangement. It can be used for preparation of peptide substrates, rhodamine dyes with phosphorylated CH2OH sites, and 3-[4-(bis-allyloxy- phosphoryloxy)-2(R)-hydroxy-3,3-dimethyl-butyrylamino]-thiopropionic acid-S-propylester and so on. It also involved in the synthesis of pharmacologically active molecules including selective orally active S1P1 agonists, water-soluble prodrugs of triazole CS-758 with antifungal activity, and fostriecin analogs as antitumor agents, and so on

Uses

Precursor involved in the synthesis of pharmacologically active molecules including:• ;Selective orally active S1P1 agonists1• ;Water-soluble prodrugs of triazole CS-758 with antifungal activity2• ;Fostriecin analogs as antitumor agents3Reactant involved in: • ;Phosphitylation of alcohols4• ;Deallylation for the synthesis of nucleoside phosphoramidite5• ;Posphitylation and stereoselective Pudovik rearrangement6

Uses

Diallyl N,N-diisopropylphosphoramidite is a reagent used in the synthesis of Leustroducsin B that exhibits large variety of biological activities. It also acts as a reagent in the synthesis of water-soluble prodrugs of triazole CS-758 with antifungal activities.

Uses

Precursor involved in the synthesis of pharmacologically active molecules including:

  • Selective orally active S1P1 agonists
  • Water-soluble prodrugs of triazole CS-758 with antifungal activity
  • Fostriecin analogs as antitumor agents

Reactant involved in:
  • Phosphitylation of alcohols
  • Deallylation for the synthesis of nucleoside phosphoramidite
  • Posphitylation and stereoselective Pudovik rearrangement

DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE Suppliers

Shureli Biopharma Co.,Ltd
Tel
0871-68355600 18787766125
Email
756338076@qq.com
Country
China
ProdList
612
Advantage
58
Qi Qi hang Biotechnology Co., Ltd.
Tel
15870833005
Email
2232044025@qq.com
Country
China
ProdList
8206
Advantage
58
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Sinocompound Catalysts Co., Ltd.
Tel
0512-67216630 18962121273
Fax
0512-56316689
Email
sales@sinocompound.com
Country
China
ProdList
278
Advantage
64
Mashilabs (Shanghai) Co.,Ltd.
Tel
19916721580
Fax
QQ:3154870176
Email
mafarm@126.com
Country
China
ProdList
4307
Advantage
58
Xinxiang Runyu Material Co., Ltd.
Tel
166-166-37336996 15690792173
Fax
0373-7759608
Email
chenxi.song@runvmat.com
Country
China
ProdList
293
Advantage
55
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
More
Less

View Lastest Price from DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Diallyl N,N-diisopropylphosphoraMidite 126429-21-8
Price
US $1.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50 tons
Release date
2020-01-17

126429-21-8, DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITERelated Search:


  • DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE
  • DIALLYL DIISOPROPYLPHOSPHORAMIDITE
  • Diallyloxy(diisopropylamino)phosphine
  • N,N-Bis(1-methylethyl)phosphoramidous acid di-2-propenyl ester
  • N-bis(prop-2-enoxy)phosphanyl-N-propan-2-ylpropan-2-amine
  • Phosphoramidous acid, N,N-bis(1-methylethyl)-, di-2-propen-1-yl ester
  • 126429-21-8
  • C12H24NO2P
  • CH32CH2NPOCH2CHCH22
  • Building Blocks
  • Phosphoramidites
  • Phosphorus Compounds
  • Organic Building Blocks
  • Organic Building Blocks
  • Phosphoramidites
  • Phosphorus Compounds
  • Building Blocks
  • Chemical Synthesis
  • Organic Building Blocks
  • Phosphorus Compounds