Phophorylating Reagent
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DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE

Phophorylating Reagent
Product Name
DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE
CAS No.
126429-21-8
Chemical Name
DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE
Synonyms
DIALLYL DIISOPROPYLPHOSPHORAMIDITE;Diallyloxy(diisopropylamino)phosphine;DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE;N-bis(prop-2-enoxy)phosphanyl-N-propan-2-ylpropan-2-amine;N,N-Bis(1-methylethyl)phosphoramidous acid di-2-propenyl ester;Phosphoramidous acid, N,N-bis(1-methylethyl)-, di-2-propen-1-yl ester
CBNumber
CB3224528
Molecular Formula
C12H24NO2P
Formula Weight
245.3
MOL File
126429-21-8.mol
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DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE Property

Boiling point:
130 °C(lit.)
Density 
0.928 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.456(lit.)
Flash point:
90 °F
storage temp. 
2-8°C
pka
4.96±0.70(Predicted)
BRN 
4383514
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Safety

Hazard Codes 
Xi
Risk Statements 
10-36/37/38
Safety Statements 
26-36
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
1-10
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
439606
Product name
Diallyl N,N-diisopropylphosphoramidite
Packaging
1g
Price
$188.4
Updated
2024/03/01
TRC
Product number
D416130
Product name
Diallyl N,N-diisopropylphosphoramidite
Packaging
100mg
Price
$140
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0156822
Product name
DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE
Purity
95.00%
Packaging
1G
Price
$672.53
Updated
2021/12/16
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DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE Chemical Properties,Usage,Production

Phophorylating Reagent

Diallyl N,N-diisopropylphosphoramidite was employed as a phophorylating reagent. It can be used for reactions involved in phosphitylation of alcohols, deallylation for the synthesis of nucleoside phosphoramidite, posphitylation and stereoselective pudovik rearrangement. It can be used for preparation of peptide substrates, rhodamine dyes with phosphorylated CH2OH sites, and 3-[4-(bis-allyloxy- phosphoryloxy)-2(R)-hydroxy-3,3-dimethyl-butyrylamino]-thiopropionic acid-S-propylester and so on. It also involved in the synthesis of pharmacologically active molecules including selective orally active S1P1 agonists, water-soluble prodrugs of triazole CS-758 with antifungal activity, and fostriecin analogs as antitumor agents, and so on

Uses

Precursor involved in the synthesis of pharmacologically active molecules including:• ;Selective orally active S1P1 agonists1• ;Water-soluble prodrugs of triazole CS-758 with antifungal activity2• ;Fostriecin analogs as antitumor agents3Reactant involved in: • ;Phosphitylation of alcohols4• ;Deallylation for the synthesis of nucleoside phosphoramidite5• ;Posphitylation and stereoselective Pudovik rearrangement6

Uses

Diallyl N,N-diisopropylphosphoramidite is a reagent used in the synthesis of Leustroducsin B that exhibits large variety of biological activities. It also acts as a reagent in the synthesis of water-soluble prodrugs of triazole CS-758 with antifungal activities.

Uses

Precursor involved in the synthesis of pharmacologically active molecules including:

  • Selective orally active S1P1 agonists
  • Water-soluble prodrugs of triazole CS-758 with antifungal activity
  • Fostriecin analogs as antitumor agents

Reactant involved in:
  • Phosphitylation of alcohols
  • Deallylation for the synthesis of nucleoside phosphoramidite
  • Posphitylation and stereoselective Pudovik rearrangement

DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Diallyl N,N-diisopropylphosphoraMidite 126429-21-8
Price
US $1.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50 tons
Release date
2020-01-17

126429-21-8, DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITERelated Search:


  • DIALLYL N,N-DIISOPROPYLPHOSPHORAMIDITE
  • DIALLYL DIISOPROPYLPHOSPHORAMIDITE
  • Diallyloxy(diisopropylamino)phosphine
  • N,N-Bis(1-methylethyl)phosphoramidous acid di-2-propenyl ester
  • N-bis(prop-2-enoxy)phosphanyl-N-propan-2-ylpropan-2-amine
  • Phosphoramidous acid, N,N-bis(1-methylethyl)-, di-2-propen-1-yl ester
  • 126429-21-8
  • C12H24NO2P
  • CH32CH2NPOCH2CHCH22
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