ChemicalBook > CAS DataBase List > (ALA11,D-LEU15)-OREXIN B (HUMAN)
(ALA11,D-LEU15)-OREXIN B (HUMAN)
- Product Name
- (ALA11,D-LEU15)-OREXIN B (HUMAN)
- CAS No.
- 532932-99-3
- Chemical Name
- (ALA11,D-LEU15)-OREXIN B (HUMAN)
- Synonyms
- Ala11,D-Leu15]-Orex;[ALA11,D-LEU15]-OREXIN B;[Ala11,D-Leu15]-Orexin B TFA;M.W. 2857.28 C120H206N44O35S;(ALA11,D-LEU15)-OREXIN B (HUMAN);RSGPPGLQGRAQRL(D-L)QASGNHAAGILTM-NH2;(Ala??,D-Leu??)-Orexin B (human) trifluoroacetate salt;ARG-SER-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-ALA-GLN-ARG-LEU-D-LEU-GLN-ALA-SER-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2;H-ARG-SER-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-ALA-GLN-ARG-LEU-D-LEU-GLN-ALA-SER-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2;(Ala11,D-Leu15)-Orexin B (human) trifluoroacetate salt H-Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Ala-Gln-Arg-Leu-D-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2 trifluoroacetate salt
- CBNumber
- CB3229109
- Molecular Formula
- C120H206N44O35S
- Formula Weight
- 2857.26
- MOL File
- 532932-99-3.mol
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(ALA11,D-LEU15)-OREXIN B (HUMAN) Property
- storage temp.
- Desiccate at -20°C
- form
- Powder
- color
- White to off-white
- Water Solubility
- Soluble to 0.30 mg/ml in water
- Sequence
- Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Ala-Gln-Arg-Leu-{dLeu}-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
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N-Bromosuccinimide Price
Tocris
- Product number
- 2142
- Product name
- [Ala11,D-Leu15]-OrexinB
- Packaging
- 1
- Price
- $382
- Updated
- 2021/12/16
Usbiological
- Product number
- 254582
- Product name
- [Ala11,D-Leu15]-Orexin B
- Packaging
- 1mg
- Price
- $644
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- PEP0004273
- Product name
- [ALA11,D-LEU15]-OREXIN B
- Purity
- 95.00%
- Packaging
- 0.5MG
- Price
- $657.2
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- PEP0004273
- Product name
- [ALA11,D-LEU15]-OREXIN B
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $797.99
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FA109685
- Product name
- (Ala11,D-Leu15)-Orexin B (human) trifluoroacetate salt H-Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Ala-Gln-Arg-Leu-D-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2 trifluoroacetate salt
- Packaging
- 2mg
- Price
- $991.3
- Updated
- 2021/12/16
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(ALA11,D-LEU15)-OREXIN B (HUMAN) Chemical Properties,Usage,Production
Uses
[Ala11,D-Leu15]-Orexin B(human) is a potent and selective orexin-2 receptor (OX2) agonist. [Ala11,D-Leu15]-Orexin B(human) shows a 400-fold selectivity for the OX2 (EC50=0.13 nM) over OX1 (52 nM)[1].
IC 50
OX2: 0.13 nM (EC50); OX1: 52 nM (EC50)
storage
-20°C
References
[1] Asahi S, et al. Development of an orexin-2 receptor selective agonist, [Ala(11), D-Leu(15)]orexin-B. Bioorg Med Chem Lett. 2003;13(1):111-113. DOI:10.1016/s0960-894x(02)00851-x
(ALA11,D-LEU15)-OREXIN B (HUMAN) Preparation Products And Raw materials
Raw materials
Preparation Products
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(ALA11,D-LEU15)-OREXIN B (HUMAN) Suppliers
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