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OREXIN B (HUMAN)

Product Name
OREXIN B (HUMAN)
CAS No.
205640-91-1
Chemical Name
OREXIN B (HUMAN)
Synonyms
HYPOCRETIN-2;Human orexin B;OREXIN B (HUMAN);HYPOCRETIN-2, HUMAN;OREXIN B HUMAN ≥98%;PubChem ID: 90479794;OREXINS OREXIN B HUMAN;OREXIN B (HUMAN) USP/EP/BP;Orexin B (human), ≥98% (HPLC);RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2
CBNumber
CB2384164
Molecular Formula
C123H212N44O35S
Formula Weight
2899.34
MOL File
205640-91-1.mol
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OREXIN B (HUMAN) Property

Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
-20°C
Water Solubility 
Soluble to 1 mg/ml in Water
Sequence
H-Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
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Safety

WGK Germany 
3
HS Code 
2937190000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SCP0204
Product name
Orexin B human
Packaging
500μG
Price
$265
Updated
2023/06/20
Sigma-Aldrich
Product number
SCP0204
Product name
Orexin B human
Packaging
1MG
Price
$377
Updated
2023/06/20
Alfa Aesar
Product number
J65110
Product name
Orexin B, human
Packaging
1mg
Price
$288
Updated
2021/12/16
Alfa Aesar
Product number
J65110
Product name
Orexin B, human
Packaging
0.5mg
Price
$165
Updated
2021/12/16
Cayman Chemical
Product number
24765
Product name
Orexin B (human) (trifluoroacetate salt)
Purity
≥95%
Packaging
500μg
Price
$347
Updated
2024/03/01
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OREXIN B (HUMAN) Chemical Properties,Usage,Production

Description

Orexin B is a hypothalamic neuropeptide that regulates feeding behavior, wakefulness, and behavior under situations of high motivational relevance. It is an agonist of orexin (OX) receptors with IC50 values of 420 and 36 nM for human recombinant OX1 and OX2 receptors, respectively, expressed in CHO cells. It induces transient increases in intracellular calcium in CHO cells stably expressing OX1 and OX2 (EC50s = 2,500 and 60 nM, respectively) and in primary rat ventral tegmental area (VTA) dopaminergic neurons. Orexin B stimulates arachidonic acid release from CHO cells expressing human recombinant OX1 (EC50 = 4.17 nM). It also stimulates food intake in freely feeding mice and goldfish when administered at intracerebroventricular doses of 30 nmol and 10 ng/g, respectively.

Biochem/physiol Actions

Orexins/Hypocretins, Orexin A/ hypocretin-1 and Orexin B/ hypocretin-2, are excitatory neuropeptides that mediate there effects via two receptors, OX-1 and OX-2. Orexins are involved in food intake, obesity regulation, energy homeostasis and differentiation.

storage

-20°C (desiccate)

OREXIN B (HUMAN) Preparation Products And Raw materials

Raw materials

Preparation Products

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OREXIN B (HUMAN) Suppliers

China 75 France 1 Germany 4 Japan 1 Switzerland 2 United Kingdom 5 United States 17 Global 105
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Cellmano Biotech Limited
Tel
0551-65326643 18156095617
Fax
0551-65326641
Email
info@cellmano.com
Country
China
ProdList
1011
Advantage
55
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Creative Peptides
Tel
Email
info@creative-peptides.com
Country
United States
ProdList
6084
Advantage
56
Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5503
Advantage
55
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 13082558573
Fax
025-58361106-806
Email
liugang@njpeptide.com
Country
China
ProdList
9961
Advantage
55
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View Lastest Price from OREXIN B (HUMAN) manufacturers

Career Henan Chemical Co
Product
OREXIN B (HUMAN) 205640-91-1
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-02-13

205640-91-1, OREXIN B (HUMAN)Related Search:

2,4-PENTANEDIONE, SILVER DERIVATIVE METHYL ISOCYANOACETATE Ethyl isocyanoacetate Aluminum acetylacetonate TERT-BUTYL ISOCYANIDE Benzyl isocyanide Ferric acetylacetonate Tris(2,4-pentanedionato)chroMiuM(III) N-BUTYLISOCYANIDE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE SALCOMINE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Tosylmethyl isocyanide TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) PHENYLSELENOL COBALT(II) ACETYLACETONATE Orexin A (bovine, human, mouse, rat)

  • REF DUPL: Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
  • Orexin B (huMan) Hypocretin-2 (huMan)
  • OREXIN B HUMAN ≥98%
  • Orexin B (human), ≥98% (HPLC)
  • PubChem ID: 90479794
  • ARG-SER-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-SER-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2
  • HYPOCRETIN-2
  • HYPOCRETIN-2, HUMAN
  • H-ARG-SER-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-SER-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2
  • RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2
  • OREXINS OREXIN B HUMAN
  • OREXIN B (HUMAN)
  • Orexin B (human) (trifluoroacetate salt)
  • Human orexin B
  • L-Methioninamide, L-arginyl-L-serylglycyl-L-prolyl-L-prolylglycyl-L-leucyl-L-glutaminylglycyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminyl-L-alanyl-L-serylglycyl-L-asparaginyl-L-histidyl-L-alanyl-L-alanylglycyl-L-isoleucyl-L-leucyl-L-threonyl-
  • OREXIN B (HUMAN) USP/EP/BP
  • 205640-91-1
  • C123H212N44O35S
  • C123H212N44O35S1
  • proteins
  • Peptide
  • Orexin receptor