OREXIN B (HUMAN)
- Product Name
- OREXIN B (HUMAN)
- CAS No.
- 205640-91-1
- Chemical Name
- OREXIN B (HUMAN)
- Synonyms
- HYPOCRETIN-2;Human orexin B;OREXIN B (HUMAN);HYPOCRETIN-2, HUMAN;OREXIN B HUMAN ≥98%;PubChem ID: 90479794;OREXINS OREXIN B HUMAN;OREXIN B (HUMAN) USP/EP/BP;Orexin B (human), ≥98% (HPLC);RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2
- CBNumber
- CB2384164
- Molecular Formula
- C123H212N44O35S
- Formula Weight
- 2899.34
- MOL File
- 205640-91-1.mol
OREXIN B (HUMAN) Property
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- Water Solubility
- Soluble to 1 mg/ml in Water
- Sequence
- H-Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
Safety
- WGK Germany
- 3
- HS Code
- 2937190000
N-Bromosuccinimide Price
- Product number
- SCP0204
- Product name
- Orexin B human
- Packaging
- 500μG
- Price
- $265
- Updated
- 2023/06/20
- Product number
- SCP0204
- Product name
- Orexin B human
- Packaging
- 1MG
- Price
- $377
- Updated
- 2023/06/20
- Product number
- J65110
- Product name
- Orexin B, human
- Packaging
- 1mg
- Price
- $288
- Updated
- 2021/12/16
- Product number
- J65110
- Product name
- Orexin B, human
- Packaging
- 0.5mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- 24765
- Product name
- Orexin B (human) (trifluoroacetate salt)
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $347
- Updated
- 2024/03/01
OREXIN B (HUMAN) Chemical Properties,Usage,Production
Description
Orexin B is a hypothalamic neuropeptide that regulates feeding behavior, wakefulness, and behavior under situations of high motivational relevance. It is an agonist of orexin (OX) receptors with IC50 values of 420 and 36 nM for human recombinant OX1 and OX2 receptors, respectively, expressed in CHO cells. It induces transient increases in intracellular calcium in CHO cells stably expressing OX1 and OX2 (EC50s = 2,500 and 60 nM, respectively) and in primary rat ventral tegmental area (VTA) dopaminergic neurons. Orexin B stimulates arachidonic acid release from CHO cells expressing human recombinant OX1 (EC50 = 4.17 nM). It also stimulates food intake in freely feeding mice and goldfish when administered at intracerebroventricular doses of 30 nmol and 10 ng/g, respectively.
Biochem/physiol Actions
Orexins/Hypocretins, Orexin A/ hypocretin-1 and Orexin B/ hypocretin-2, are excitatory neuropeptides that mediate there effects via two receptors, OX-1 and OX-2. Orexins are involved in food intake, obesity regulation, energy homeostasis and differentiation.
storage
-20°C (desiccate)
OREXIN B (HUMAN) Preparation Products And Raw materials
Raw materials
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View Lastest Price from OREXIN B (HUMAN) manufacturers
- Product
- OREXIN B (HUMAN) 205640-91-1
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-02-13