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OREXIN B (HUMAN)

Product Name
OREXIN B (HUMAN)
CAS No.
205640-91-1
Chemical Name
OREXIN B (HUMAN)
Synonyms
HYPOCRETIN-2;Human orexin B;OREXIN B (HUMAN);HYPOCRETIN-2, HUMAN;OREXIN B HUMAN ≥98%;PubChem ID: 90479794;OREXINS OREXIN B HUMAN;OREXIN B (HUMAN) USP/EP/BP;Orexin B (human), ≥98% (HPLC);RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2
CBNumber
CB2384164
Molecular Formula
C123H212N44O35S
Formula Weight
2899.34
MOL File
205640-91-1.mol
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OREXIN B (HUMAN) Property

Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
-20°C
Water Solubility 
Soluble to 1 mg/ml in Water
Sequence
H-Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
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Safety

WGK Germany 
3
HS Code 
2937190000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SCP0204
Product name
Orexin B human
Packaging
500μG
Price
$265
Updated
2023/06/20
Sigma-Aldrich
Product number
SCP0204
Product name
Orexin B human
Packaging
1MG
Price
$377
Updated
2023/06/20
Alfa Aesar
Product number
J65110
Product name
Orexin B, human
Packaging
1mg
Price
$288
Updated
2021/12/16
Alfa Aesar
Product number
J65110
Product name
Orexin B, human
Packaging
0.5mg
Price
$165
Updated
2021/12/16
Cayman Chemical
Product number
24765
Product name
Orexin B (human) (trifluoroacetate salt)
Purity
≥95%
Packaging
500μg
Price
$347
Updated
2024/03/01
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OREXIN B (HUMAN) Chemical Properties,Usage,Production

Description

Orexin B is a hypothalamic neuropeptide that regulates feeding behavior, wakefulness, and behavior under situations of high motivational relevance. It is an agonist of orexin (OX) receptors with IC50 values of 420 and 36 nM for human recombinant OX1 and OX2 receptors, respectively, expressed in CHO cells. It induces transient increases in intracellular calcium in CHO cells stably expressing OX1 and OX2 (EC50s = 2,500 and 60 nM, respectively) and in primary rat ventral tegmental area (VTA) dopaminergic neurons. Orexin B stimulates arachidonic acid release from CHO cells expressing human recombinant OX1 (EC50 = 4.17 nM). It also stimulates food intake in freely feeding mice and goldfish when administered at intracerebroventricular doses of 30 nmol and 10 ng/g, respectively.

Biochem/physiol Actions

Orexins/Hypocretins, Orexin A/ hypocretin-1 and Orexin B/ hypocretin-2, are excitatory neuropeptides that mediate there effects via two receptors, OX-1 and OX-2. Orexins are involved in food intake, obesity regulation, energy homeostasis and differentiation.

storage

-20°C (desiccate)

OREXIN B (HUMAN) Preparation Products And Raw materials

Raw materials

Preparation Products

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OREXIN B (HUMAN) Suppliers

China 76 France 1 Germany 4 Japan 1 Switzerland 2 United Kingdom 5 United States 17 Global 106
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View Lastest Price from OREXIN B (HUMAN) manufacturers

Career Henan Chemical Co
Product
OREXIN B (HUMAN) 205640-91-1
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-02-13

205640-91-1, OREXIN B (HUMAN)Related Search:

2,4-PENTANEDIONE, SILVER DERIVATIVE METHYL ISOCYANOACETATE Ethyl isocyanoacetate Aluminum acetylacetonate TERT-BUTYL ISOCYANIDE Benzyl isocyanide Ferric acetylacetonate Tris(2,4-pentanedionato)chroMiuM(III) N-BUTYLISOCYANIDE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE SALCOMINE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Tosylmethyl isocyanide TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) PHENYLSELENOL COBALT(II) ACETYLACETONATE Orexin A (bovine, human, mouse, rat)

  • REF DUPL: Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
  • Orexin B (huMan) Hypocretin-2 (huMan)
  • OREXIN B HUMAN ≥98%
  • Orexin B (human), ≥98% (HPLC)
  • PubChem ID: 90479794
  • ARG-SER-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-SER-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2
  • HYPOCRETIN-2
  • HYPOCRETIN-2, HUMAN
  • H-ARG-SER-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-SER-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2
  • RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2
  • OREXINS OREXIN B HUMAN
  • OREXIN B (HUMAN)
  • Orexin B (human) (trifluoroacetate salt)
  • Human orexin B
  • L-Methioninamide, L-arginyl-L-serylglycyl-L-prolyl-L-prolylglycyl-L-leucyl-L-glutaminylglycyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminyl-L-alanyl-L-serylglycyl-L-asparaginyl-L-histidyl-L-alanyl-L-alanylglycyl-L-isoleucyl-L-leucyl-L-threonyl-
  • OREXIN B (HUMAN) USP/EP/BP
  • 205640-91-1
  • C123H212N44O35S
  • C123H212N44O35S1
  • proteins
  • Peptide
  • Orexin receptor