1-Butylpyrrolidine Property

Boiling point:

155-157 °C/754 mmHg (lit.)

Density 

0.814 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.44(lit.)

Flash point:

97 °F

storage temp. 

Refrigerator, Under inert atmosphere

solubility 

Chloroform (Sparingly), Ethyl Acetate (Slightly)

pka

10.62±0.20(Predicted)

form 

Oil

color 

Colourless

LogP

2.209 (est)

CAS DataBase Reference

767-10-2(CAS DataBase Reference)

NIST Chemistry Reference

1-Butylpyrrolidine(767-10-2)

Safety

Hazard Codes 

T

Risk Statements 

10-24/25

Safety Statements 

16-36/37-45

RIDADR 

UN 2929 6.1/PG 2

WGK Germany 

2

RTECS 

UX9800000

HazardClass 

3.2

PackingGroup 

III

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

1-Butylpyrrolidine Chemical Properties,Usage,Production

Uses

1-Butylpyrrolidine can be used in the composition for alcohol recovery solution.

Uses

1-Butylpyrrolidine has been used in:
microwave-assisted synthesis of ionic liquid precursor, 1-butyl-1-methylpyrrolidinium methylcarbonate.
[N,N-methylbutylpyrrolidinium] thiosalicylate, ionic liquid.
The reaction of 1-butylpyrrolidine with dimethyl carbonate to yield the ionic liquid precursor, 1-butyl-1-methylpyrrolidinium methylcarbonate, has been investigated under microwave heating conditions and the reaction parameters optimised to achieve 100% yield of the pyrrolidinium salt with no by-products in under 1h.

Preparation

The synthesis of 1-butylpyrrolidine and its derivatives (1-butylpyrrolidine with a little of 1-butenylpyrrolidines) was developed via a one-pot method from ammonia and 1,4-butandiol. Here, the product of 1-butylpyrrolidine was emphatically investigated, and the yield was 76% under the optimized conditions. Such a route was realized through successive N-alkylation using aqueous ammonia as the nitrogen source over the CuNiPd/ZSM-5 catalyst, which was prepared by a simple incipient wetness method. In this route, 1,4-butandiol not only participated in the formation of the N-heterocycle, but also acted as an alkylating reagent. This work offers a straightforward, economical route for 1-butylpyrrolidine and its derivatives.

One-pot synthesis of 1-butylpyrrolidine and its derivatives from aqueous ammonia and 1,4-butandiol over CuNiPd/ZSM-5 catalysts