ChemicalBook > CAS DataBase List > ETHYL 5-PHENYL-3-ISOXAZOLECARBOXYLATE

ETHYL 5-PHENYL-3-ISOXAZOLECARBOXYLATE

Product Name
ETHYL 5-PHENYL-3-ISOXAZOLECARBOXYLATE
CAS No.
13599-24-1
Chemical Name
ETHYL 5-PHENYL-3-ISOXAZOLECARBOXYLATE
Synonyms
TIMTEC-BB SBB014614;ethyl 3-phenyl-5-isoxazolecarboxylate
CBNumber
CB32446692
Molecular Formula
C12H11NO3
Formula Weight
217.22
MOL File
13599-24-1.mol
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ETHYL 5-PHENYL-3-ISOXAZOLECARBOXYLATE Property

Melting point:
47 °C
Boiling point:
379.8±30.0 °C(Predicted)
Density 
1.173±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
-4.43±0.50(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
E926728
Product name
Ethyl3-Phenylisoxazole-5-carboxylate
Packaging
1g
Price
$330
Updated
2021/12/16
AK Scientific
Product number
6412AA
Product name
Ethyl3-phenylisoxazole-5-carboxylate
Packaging
1g
Price
$226
Updated
2021/12/16
Matrix Scientific
Product number
040787
Product name
Ethyl 3-phenylisoxazole-5-carboxylate
Packaging
1g
Price
$250
Updated
2021/12/16
Matrix Scientific
Product number
040787
Product name
Ethyl 3-phenylisoxazole-5-carboxylate
Packaging
5g
Price
$750
Updated
2021/12/16
Ambeed
Product number
A171415
Product name
Ethyl3-phenylisoxazole-5-carboxylate
Purity
97%
Packaging
250mg
Price
$25
Updated
2021/12/16
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ETHYL 5-PHENYL-3-ISOXAZOLECARBOXYLATE Chemical Properties,Usage,Production

Synthesis

81745-44-0

623-47-2

13599-24-1

General procedure for the synthesis of ethyl 3-phenylisoxazole-5-carboxylate from (E)-N-hydroxybenzimidoyl chloride and ethyl propargylate: preparation of the intermediate 54-ethyl S-phenylisoxazole-δ-carboxylic acid ethyl ester. The reaction was carried out by stirring ethyl propiolate (0.657 mL, 6.43 mmol), (E)-N-hydroxybenzenecarboximidoyl chloride (0.500 g, 3.21 mmol), and sodium bicarbonate (0.818 g, 9.64 mmol) in a mixed solvent of ethyl acetate (16 mL) and water (1 mL) at room temperature overnight. After completion of the reaction, the reaction mixture was filtered and the filtrate was concentrated under reduced pressure. The crude product was purified by fast column chromatography on silica gel, the eluent being a heptane solution of 5% to 80% dichloromethane, to give 0.295 g of ethyl 3-phenylisoxazole-5-carboxylate in 42% yield.ESI/APCI (+): 218 (M + H).

References

[1] Patent: WO2010/142801, 2010, A1. Location in patent: Page/Page column 162-163

ETHYL 5-PHENYL-3-ISOXAZOLECARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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ETHYL 5-PHENYL-3-ISOXAZOLECARBOXYLATE Suppliers

Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
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View Lastest Price from ETHYL 5-PHENYL-3-ISOXAZOLECARBOXYLATE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
3-Phenylisoxazole-5-carboxylic acid 13599-24-1
Price
US $2.20-8.80/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-17
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
ETHYL 3-PHENYLISOXAZOLE-5-CARBOXYLATE 13599-24-1
Price
US $2.20-8.80/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-17