AC-5216

Product Name: AC-5216
CAS No.: 226954-04-7
Chemical Name: AC-5216
Synonyms: CS-2606;AC-5216;XBD-173;Mapunil;EMapunil;AC-5216,XBD-173;Emapunil(AC-5216);AC 5216 (Emapunil);XBD173 >=98% (HPLC);AC-5216;XBD-173;EMAPUNIL;AC5216;AC 5216
CBNumber: CB32448636
Molecular Formula: C23H23N5O2
Formula Weight: 401.46
MOL File: 226954-04-7.mol

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AC-5216 Property

storage temp.: 2-8°C
solubility: DMF: 30 mg/mL; DMF:PBS (pH 7.2) (1:20): 0.05 mg/mL; DMSO: 5 mg/mL
form: powder
color: white to beige

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1223
Product name: XBD173
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $118
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML1223
Product name: XBD173
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $462
Updated: 2024/03/01

Cayman Chemical

Product number: 18522
Product name: AC-5216
Purity: ≥98%
Packaging: 1mg
Price: $34
Updated: 2024/03/01

Cayman Chemical

Product number: 18522
Product name: AC-5216
Purity: ≥98%
Packaging: 5mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 18522
Product name: AC-5216
Purity: ≥98%
Packaging: 10mg
Price: $183
Updated: 2024/03/01

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AC-5216 Chemical Properties,Usage,Production

Uses

Emapunil possesses anxiolytic and antidepressant-like effects and a ligand for translocator protein (TSPO), which plays an important role in the depression treatment.

Biochem/physiol Actions

XBD173 (emapunil, AC-5216) is a potent and selective translocator protein 18 kDa (TSPO) ligand with a Ki value of 0.297 nM. XBD173 acts at the TSPO translocator protein, formerly called the peripheral benzodiazepine receptor, which is involved in production of neuroactive steroids such as allopregnanolone in the brain. TSPO carries cholesterol from the outer to the inner mitochondrial membrane, which is the rate-limiting step of steroidogenesis. XBD173 enhances GABA-mediated neurotransmission via induction of neurosteroidogenesis and exhibits anti-anxiety and antidepressant-like effects.

storage

Store at +4°C

AC-5216 Preparation Products And Raw materials

Raw materials

Preparation Products

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AC-5216 Suppliers

China 78 India 1 United Kingdom 3 United States 14 Global 96

Shanghai Boyle Chemical Co., Ltd.

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Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 9387
Advantage: 52

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9648
Advantage: 58

HangZhou YuHao Chemical Technology Co., Ltd.

Tel: 0571-82693216
Fax: 0571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 2028
Advantage: 58

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Chizhou Kailong Import and Export Trade Co., Ltd.

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Email: xg01_gj@163.com
Country: China
ProdList: 9484
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Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4575
Advantage: 55

226954-04-7, AC-5216Related Search:

2-PHENYLPYRIMIDIN-5-AMINE AC-5216

EMapunil

XBD-173

N-Benzyl-N-ethyl-2-(7-Methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetaMide

9H-Purine-9-acetaMide,N-ethyl-7,8-dihydro-7-Methyl-8-oxo-2-phenyl-N-(phenylMethyl)-

AC 5216 (Emapunil)

N-Ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-9H-purine-9-acetamide

Emapunil(AC-5216)

AC-5216

CS-2606

AC-5216;XBD-173;EMAPUNIL;AC5216;AC 5216

XBD173 >=98% (HPLC)

9H-Purine-9-acetaMide,N-ethyl-7,8-dihydro-7-Methyl-8-oxoChemicalbook-2-phenyl-N-(phenylMethyl)-

Mapunil

N-benzyl-N-ethyl-2-(7-methyl-8-oxo-2-phenyl-7H-purin-9(8H)-yl)acetamide

PTSD,depression,T2DM,AC 5216,antianxiety,Emapunil,XBD 173,disorder,traumatic,MBR,neuroprotective,inhibit,post,XBD173,Antidepressant,AC5216,Inhibitor,stress,anti-inflammatory

AC-5216,XBD-173

N-benzyl-N-ethyl-2-(7-methyl-8-oxo-2-phenylpurin-9-yl)acetamide

226954-04-7

Inhibitors