ChemicalBook > CAS DataBase List > AC-5216

AC-5216

Product Name
AC-5216
CAS No.
226954-04-7
Chemical Name
AC-5216
Synonyms
CS-2606;AC-5216;XBD-173;Mapunil;EMapunil;AC-5216,XBD-173;Emapunil(AC-5216);AC 5216 (Emapunil);XBD173 >=98% (HPLC);AC-5216;XBD-173;EMAPUNIL;AC5216;AC 5216
CBNumber
CB32448636
Molecular Formula
C23H23N5O2
Formula Weight
401.46
MOL File
226954-04-7.mol
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AC-5216 Property

storage temp. 
2-8°C
solubility 
DMF: 30 mg/mL; DMF:PBS (pH 7.2) (1:20): 0.05 mg/mL; DMSO: 5 mg/mL
form 
powder
color 
white to beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1223
Product name
XBD173
Purity
≥98% (HPLC)
Packaging
5MG
Price
$118
Updated
2024/03/01
Sigma-Aldrich
Product number
SML1223
Product name
XBD173
Purity
≥98% (HPLC)
Packaging
25MG
Price
$462
Updated
2024/03/01
Cayman Chemical
Product number
18522
Product name
AC-5216
Purity
≥98%
Packaging
1mg
Price
$34
Updated
2024/03/01
Cayman Chemical
Product number
18522
Product name
AC-5216
Purity
≥98%
Packaging
5mg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
18522
Product name
AC-5216
Purity
≥98%
Packaging
10mg
Price
$183
Updated
2024/03/01
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AC-5216 Chemical Properties,Usage,Production

Uses

Emapunil possesses anxiolytic and antidepressant-like effects and a ligand for translocator protein (TSPO), which plays an important role in the depression treatment.

Biochem/physiol Actions

XBD173 (emapunil, AC-5216) is a potent and selective translocator protein 18 kDa (TSPO) ligand with a Ki value of 0.297 nM. XBD173 acts at the TSPO translocator protein, formerly called the peripheral benzodiazepine receptor, which is involved in production of neuroactive steroids such as allopregnanolone in the brain. TSPO carries cholesterol from the outer to the inner mitochondrial membrane, which is the rate-limiting step of steroidogenesis. XBD173 enhances GABA-mediated neurotransmission via induction of neurosteroidogenesis and exhibits anti-anxiety and antidepressant-like effects.

storage

Store at +4°C

AC-5216 Preparation Products And Raw materials

Raw materials

Preparation Products

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AC-5216 Suppliers

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226954-04-7, AC-5216Related Search:

2-PHENYLPYRIMIDIN-5-AMINE AC-5216

  • EMapunil
  • XBD-173
  • N-Benzyl-N-ethyl-2-(7-Methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetaMide
  • 9H-Purine-9-acetaMide,N-ethyl-7,8-dihydro-7-Methyl-8-oxo-2-phenyl-N-(phenylMethyl)-
  • AC 5216 (Emapunil)
  • N-Ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)-9H-purine-9-acetamide
  • Emapunil(AC-5216)
  • AC-5216
  • CS-2606
  • AC-5216;XBD-173;EMAPUNIL;AC5216;AC 5216
  • XBD173 >=98% (HPLC)
  • 9H-Purine-9-acetaMide,N-ethyl-7,8-dihydro-7-Methyl-8-oxoChemicalbook-2-phenyl-N-(phenylMethyl)-
  • Mapunil
  • N-benzyl-N-ethyl-2-(7-methyl-8-oxo-2-phenyl-7H-purin-9(8H)-yl)acetamide
  • PTSD,depression,T2DM,AC 5216,antianxiety,Emapunil,XBD 173,disorder,traumatic,MBR,neuroprotective,inhibit,post,XBD173,Antidepressant,AC5216,Inhibitor,stress,anti-inflammatory
  • AC-5216,XBD-173
  • 226954-04-7
  • Inhibitors