1,3-BENZOXAZOLE-5-CARBOXYLIC ACID
- Product Name
- 1,3-BENZOXAZOLE-5-CARBOXYLIC ACID
- CAS No.
- 15112-41-1
- Chemical Name
- 1,3-BENZOXAZOLE-5-CARBOXYLIC ACID
- Synonyms
- OTAVA-BB 1023215;5-Benzoxazolecarboxylic acid;Benzoxazole-5-carboxylic Acid;1,3-BENZOXAZOLE-5-CARBOXYLIC ACID;Benzo[d]oxazole-5-carboxylic acid;1,3-benzoxazole-5-carboxylic acid、 5-Benzoxazolecarboxylic acid
- CBNumber
- CB32453346
- Molecular Formula
- C8H5NO3
- Formula Weight
- 163.13
- MOL File
- 15112-41-1.mol
1,3-BENZOXAZOLE-5-CARBOXYLIC ACID Property
- Melting point:
- 241-242℃
- Boiling point:
- 350.1±15.0 °C(Predicted)
- Density
- 1.455
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- pka
- 3.50±0.30(Predicted)
- Appearance
- Off-white to light yellow Solid
- InChI
- InChI=1S/C8H5NO3/c10-8(11)5-1-2-7-6(3-5)9-4-12-7/h1-4H,(H,10,11)
- InChIKey
- WJBOXEGAWJHKIM-UHFFFAOYSA-N
- SMILES
- O1C2=CC=C(C(O)=O)C=C2N=C1
Safety
- WGK Germany
- WGK 3
- HS Code
- 2934999090
- Storage Class
- 11 - Combustible Solids
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CDS010065
- Product name
- 1,3-benzoxazole-5-carboxylic acid
- Purity
- AldrichCPR
- Packaging
- 50MG
- Price
- $114
- Updated
- 2026/03/19
- Product number
- B130150
- Product name
- Benzo[d]oxazole-5-carboxylicAcid
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- OR907912
- Product name
- 1,3-benzoxazole-5-carboxylicacid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- OR907912
- Product name
- 1,3-benzoxazole-5-carboxylicacid
- Purity
- 98%
- Packaging
- 1g
- Price
- $155
- Updated
- 2021/12/16
- Product number
- Z4196
- Product name
- Benzo[d]oxazole-5-carboxylicacid
- Packaging
- 1g
- Price
- $184
- Updated
- 2021/12/16
1,3-BENZOXAZOLE-5-CARBOXYLIC ACID Chemical Properties,Usage,Production
Synthesis
149-73-5
1571-72-8
15112-41-1
Synthesis of benzoxazole-5-carboxylic acid: 3-amino-4-hydroxybenzoic acid (500 mg, 3.26 mmol) was mixed with trimethyl orthoformate (5 mL) under argon protection and the reaction was heated at 65°C for 2 hours. After completion of the reaction, the mixture was cooled to room temperature, filtered and washed with hexane. The filtrate was concentrated in vacuum to give a white solid product benzoxazole-5-carboxylic acid (78 mg, 15% yield). The product was characterized by the following data: 1H NMR (500 MHz, CDCl3): δ 8.57 (d, J = 1.5 Hz, 1H), 8.20 (dd, J = 8.4, 1.8 Hz, 1H), 8.20 (s, 1H), 7.67 (d, J = 9.0 Hz, 1H). Mass spectrum (MS): m/z 164 (M + H).
References
[1] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 24, p. 8219 - 8248
[2] Patent: US2005/84506, 2005, A1. Location in patent: Page/Page column 40
[3] Patent: EP1229027, 2002, A1. Location in patent: Page 18
[4] Patent: EP1229028, 2002, A1. Location in patent: Page 18
[5] Patent: EP1229037, 2002, A1. Location in patent: Page 17
1,3-BENZOXAZOLE-5-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,3-BENZOXAZOLE-5-CARBOXYLIC ACID manufacturers
- Product
- 1,3-benzoxazole-5-carboxylic acid 15112-41-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.4%
- Supply Ability
- 100 tons
- Release date
- 2022-02-08
- Product
- 1,3-BENZOXAZOLE-5-CARBOXYLIC ACID 15112-41-1
- Price
- US $30.00-1000.00/G
- Min. Order
- 1G
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2018-08-03