3-BOC-AMINO-PYRROLIDIN-2-ONE

Product Name: 3-BOC-AMINO-PYRROLIDIN-2-ONE
CAS No.: 99780-97-9
Chemical Name: 3-BOC-AMINO-PYRROLIDIN-2-ONE
Synonyms: 3-BOC-AMINO-PYRROLIDIN-2-ONE;tert-Butyl (2-oxopyrrolidin-3-yl);tert-butyl N-(2-oxopyrrolidin-3-yl)carbamate;Carbamic acid, N-(2-oxo-3-pyrrolidinyl)-, 1,1-dimethylethyl ester
CBNumber: CB32455108
Molecular Formula: C9H16N2O3
Formula Weight: 200.23
MOL File: 99780-97-9.mol

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3-BOC-AMINO-PYRROLIDIN-2-ONE Property

Boiling point:: 394.0±31.0 °C(Predicted)
Density: 1.13±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 11.05±0.20(Predicted)
Appearance: White to off-white Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

AK Scientific

Product number: Z6019
Product name: 3-Boc-amino-pyrrlidin-2-one
Packaging: 1g
Price: $331
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0095957
Product name: 3-BOC-AMINO-PYRROLIDIN-2-ONE
Purity: 95.00%
Packaging: 5MG
Price: $495.19
Updated: 2021/12/16

Matrix Scientific

Product number: 132798
Product name: tert-Butyl2-oxopyrrolidin-3-ylcarbamate
Purity: 97%
Packaging: 1g
Price: $933
Updated: 2021/12/16

Matrix Scientific

Product number: 132798
Product name: tert-Butyl2-oxopyrrolidin-3-ylcarbamate
Purity: 97%
Packaging: 5g
Price: $3214
Updated: 2021/12/16

Chemenu

Product number: CM119024
Product name: 3-(Boc-amino)pyrrolidin-2-one
Purity: 97%
Packaging: 1g
Price: $239
Updated: 2021/12/16

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3-BOC-AMINO-PYRROLIDIN-2-ONE Chemical Properties,Usage,Production

Synthesis

24424-99-5

2483-65-0

99780-97-9

To a mixed methanol and triethylamine solution (9:1, 130 mL, v/v) of 3-aminopyrrolidin-2-one (39) (2.8 g, 28 mmol), di-tert-butyl dicarbonate (6.7 g, 30.8 mmol) was added. The reaction mixture was stirred overnight at room temperature and then heated to reflux for 2 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure and the resulting solid was collected by filtration and washed with ether to afford 3-(Boc-amino)pyrrolidin-2-one in 97% yield.

References

[1] Patent: US2005/165065, 2005, A1. Location in patent: Page/Page column 24
[2] Patent: WO2017/75056, 2017, A1. Location in patent: Paragraph 0371
[3] Journal of Medicinal Chemistry, 1986, vol. 29, # 2, p. 251 - 260
[4] Patent: US6441017, 2002, B1

3-BOC-AMINO-PYRROLIDIN-2-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BOC-AMINO-PYRROLIDIN-2-ONE Suppliers

China 46 India 1 United States 11 Global 58

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99780-97-9, 3-BOC-AMINO-PYRROLIDIN-2-ONERelated Search:

(S)-(3-N-BOC-AMINO-2-OXO-PYRROLIDIN-1-YL)-ACETIC ACID RARECHEM EM WB 0257 2-(3-(TERT-BUTOXYCARBONYLAMINO)-2-OXOPYRROLIDIN-1-YL)ACETICACID 3-BOC-AMINO-PYRROLIDIN-2-ONE (R)-3-(BOC-AMINO)-2-OXO-1-PYRROLIDINE-ACETIC ACID (S)-BOC-3-AMINO-2-PYRROLIDINONE

3-BOC-AMINO-PYRROLIDIN-2-ONE

Carbamic acid, N-(2-oxo-3-pyrrolidinyl)-, 1,1-dimethylethyl ester

tert-Butyl (2-oxopyrrolidin-3-yl)

tert-butyl N-(2-oxopyrrolidin-3-yl)carbamate

99780-97-9