5-CHLORO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE

Product Name: 5-CHLORO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE
CAS No.: 27187-13-9
Chemical Name: 5-CHLORO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE
Synonyms: Nsc289808;5-CHLORO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE;1,2,4-TRIAZOLO[4,3-A]PYRIDINE, 5-CHLORO-;5-Chloro-1,2,4-triazolo[4,3-a]pyridine,97%;5-Chloro-[1,2,4]triazolo[4,3-a]pyridine
CBNumber: CB32455946
Molecular Formula: C6H4ClN3
Formula Weight: 153.57
MOL File: 27187-13-9.mol

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5-CHLORO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE Property

Melting point:: 87-89 °C
Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 1.97±0.50(Predicted)
form: Solid
Appearance: Brown to reddish brown Solid

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SYX00172
Product name: 5-Chloro-[1,2,4]triazolo[4,3-a]pyridine
Purity: Aldrich
Packaging: 1g
Price: $475
Updated: 2025/07/31

TRC

Product number: C384393
Product name: 5-Chloro-[1,2,4]triazolo[4,3-A]pyridine
Packaging: 100mg
Price: $90
Updated: 2021/12/16

Apolloscientific

Product number: OR909064
Product name: 5-chloro-[1,2,4]triazolo[4,3-a]pyridine
Purity: 95%
Packaging: 250mg
Price: $130
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-5-QE
Product name: 5-Chloro-[1,2,4]triazolo[4,3-a]pyridine
Purity: 95%
Packaging: 1g
Price: $480
Updated: 2021/12/16

Matrix Scientific

Product number: 069856
Product name: 5-Chloro-[1,2,4]triazolo[4,3-a]pyridine
Purity: 98%
Packaging: 1g
Price: $492
Updated: 2021/12/16

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5-CHLORO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE Chemical Properties,Usage,Production

Synthesis

5193-03-3

122-51-0

27187-13-9

General procedure for the synthesis of 5-chloro-[1,2,4]triazolo[4,3-a]pyridine from 2-chloro-6-hydrazinylpyridine and triethyl orthoformate: 2-chloro-6-hydrazinylpyridine (3.0 g, 20.9 mmol) and triethyl orthoformate (20 mL, 120.2 mmol) were added to a 125 mL round bottom flask. The reaction mixture was heated to reflux for 4 hours, then cooled to room temperature and allowed to stand overnight. The mixture was concentrated to dryness under reduced pressure and trichlorophosphate (50 mL) was added. The mixture was refluxed overnight. Upon completion of the reaction, the reaction solution was quenched in an ice bath and washed with dichloromethane (CH2Cl2). The aqueous phase was adjusted to pH 6 with 1 N sodium hydroxide solution and subsequently extracted with dichloromethane. The organic phases were combined, concentrated under reduced pressure and purified by silica gel column chromatography, eluting sequentially with 100% ethyl acetate (500 mL) and 5% methanol/dichloromethane to afford 5-chloro-[1,2,4]triazolo[4,3-a]pyridine (1.73 g, 11.25 mmol, 53% yield) as a solid.

References

[1] Patent: WO2008/118718, 2008, A2. Location in patent: Page/Page column 119

5-CHLORO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-CHLORO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE Suppliers

China 52 India 2 United States 7 Global 61

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View Lastest Price from 5-CHLORO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 1,2,4-Triazolo[4,3-a]pyridine,5-chloro- 27187-13-9
Price: US $1.10-9.90/KG
Min. Order: 1KG
Purity: 99% min
Supply Ability: 100kg
Release date: 2025-08-18

27187-13-9, 5-CHLORO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINERelated Search:

5-Chloro-[1,2,4]triazolo[1,5-a]pyrazine 5-Chloro-[1,2,4]triazolo[1,5-a]pyridine 3-a]pyrazine Diclobutrazol 5-CHLORO-3-(CHLOROMETHYL)[1,2,4]TRIAZOLO[4,3-A]PYRIDINE 1,2,4-TRIAZOLO[4,3-A]PYRIDINE, 5-CHLORO-3-METHYL- 5-CHLORO-3-ETHYL[1,2,4]TRIAZOLO[4,3-A]PYRIDINE 5-CHLORO-3-(4-CHLOROPHENYL)[1,2,4]TRIAZOLO[4,3-A]PYRIDINE 3-(TERT-BUTYL)-5-CHLORO[1,2,4]TRIAZOLO[4,3-A]PYRIDINE 5-CHLORO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE

1,2,4-TRIAZOLO[4,3-A]PYRIDINE, 5-CHLORO-

5-CHLORO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE

Nsc289808

5-Chloro-1,2,4-triazolo[4,3-a]pyridine,97%

5-Chloro-[1,2,4]triazolo[4,3-<i>a</i>]pyridine

27187-13-9