Treprostinil Sodium

Product Name: Treprostinil Sodium
CAS No.: 289480-64-4
Chemical Name: Treprostinil Sodium
Synonyms: Troprostil sodium;UT 15 (pharMaceutical);Treprostinil Sodium API;Treprostinil sodium salt;Treprostinil Sodium (UT-15);Treprostinil sodium (LRX15);289480-64-4 Treprostinil Sodium;Prostaglandin Receptor,UT15,Treprostinil Sodium,inhibit,Treprostinil,UT 15,Inhibitor;2-(((1R,2R,3aS,9aS)-2-Hydroxy-1-((S)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl)oxy)acetic acid, sodium salt;Treprostinil 13C2 D1 Sodium SaltQ: What is Treprostinil 13C2 D1 Sodium Salt Q: What is the CAS Number of Treprostinil 13C2 D1 Sodium Salt Q: What is the storage condition of Treprostinil 13C2 D1 Sodium Salt Q: What are the applications of Treprostinil 13C2 D1 Sodium Salt
CBNumber: CB32460050
Molecular Formula: C23H35NaO5
Formula Weight: 414.52
MOL File: 289480-64-4.mol

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Treprostinil Sodium Property

storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO : ≥ 26 mg/mL (63.03 mM)
form: solid
color: White
InChIKey: XUACDQZEUSYNGG-DJYDVLTONA-N
SMILES: C([C@H]1[C@@H](C[C@]2([H])CC3=C(C=CC=C3C[C@]12[H])OCC(=O)O)O)C[C@@H](O)CCCCC.[NaH] |&1:1,2,4,14,23,r|

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Safety

HS Code: 2918999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-6170
Product name: Treprostinilsodium
Purity: >98.0%
Packaging: 1mg
Price: $84
Updated: 2021/12/16

Apolloscientific

Product number: BISN0021
Product name: TreprostinilSodium
Purity: 97%
Packaging: 1mg
Price: $116
Updated: 2021/12/16

AK Scientific

Product number: Y0243
Product name: Treprostinilsodium
Packaging: 5mg
Price: $196
Updated: 2021/12/16

ChemScene

Product number: CS-6170
Product name: Treprostinilsodium
Purity: >98.0%
Packaging: 5mg
Price: $264
Updated: 2021/12/16

Apolloscientific

Product number: BISN0021
Product name: TreprostinilSodium
Purity: 97%
Packaging: 5mg
Price: $319
Updated: 2021/12/16

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Treprostinil Sodium Chemical Properties,Usage,Production

Description

Treprostinil sodium is a chemically stable prostacyclin analogue that shares at least some of the pharmacologic actions of epoprostenol. The sodium salt of treprostinil is currently approved for the treatment of PAH for either parenteral (Remodulin) or inhaled (Tyvaso) routes of administration. Acute hemodynamic effects with treprostinil are similar to those observed with intravenous epoprostenol in patients with IPAH; however, treprostinil is stable at room temperature and neutral pH and has a longer half-life, 2–3 hours, when administered subcutaneously. Like epoprostenol, treprostinil is infused continuously by a portable pump and can be administered subcutaneously or intravenously. Treprostinil was approved in 2002 for subcutaneous infusion and in 2004 for intravenous injection[1].

Uses

Treprostinil sodium is a potent agonist of DP1, EP2 and IP receptors with Ki 4.4 nM, 3.6 nM and 32 nM, respectively.

Definition

ChEBI: Treprostinil sodium is an organic sodium salt. It contains a treprostinil.

References

[1] Zhi-Cheng Jing. “Efficacy and safety of oral treprostinil monotherapy for the treatment of pulmonary arterial hypertension: a randomized, controlled trial.” Circulation 127 5 (2013): 624–33.

Treprostinil Sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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Treprostinil Sodium Suppliers

China 80 India 4 United States 8 Global 92

Chemvon Biotechnology Co., Ltd

Tel: 021-50790412
Fax: +86-21-50790419
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Country: China
ProdList: 371
Advantage: 57

Shanghai Chaolan Chemical Technology Center

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JinYan Chemicals(ShangHai) Co.,Ltd.

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Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
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Advantage: 60

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
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Shanghai Hanhong Scientific Co.,Ltd.

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Country: China
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XiaoGan ShenYuan ChemPharm co,ltd

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Country: China
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Shanghai T&W Pharmaceutical Co., Ltd.

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MedChemexpress LLC

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Nanjing Sunlida Biological Technology Co., Ltd.

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View Lastest Price from Treprostinil Sodium manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: treprostinil sodium 289480-64-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-26

Career Henan Chemical Co

Product: REMODULIN 289480-64-4
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg -1000kg
Release date: 2020-01-02

289480-64-4, Treprostinil SodiumRelated Search:

REMODULIN 2-[[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[g]naphthalen-5-yl]oxy]acetic acid,2-(2-hydroxyethylamino)ethanol 2,3-DIMETHYLPHENOXYACETIC ACID REMODULIN

Treprostinil Sodium API

Treprostinil Sodium (UT-15)

UT 15 (pharMaceutical)

Treprostinil sodium salt

289480-64-4 Treprostinil Sodium

Treprostinil sodium (LRX15)

Treprostinil 13C2 D1 Sodium SaltQ: What is Treprostinil 13C2 D1 Sodium Salt Q: What is the CAS Number of Treprostinil 13C2 D1 Sodium Salt Q: What is the storage condition of Treprostinil 13C2 D1 Sodium Salt Q: What are the applications of Treprostinil 13C2 D1 Sodium Salt

2-(((1R,2R,3aS,9aS)-2-Hydroxy-1-((S)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl)oxy)acetic acid, sodium salt

Troprostil sodium

Prostaglandin Receptor,UT15,Treprostinil Sodium,inhibit,Treprostinil,UT 15,Inhibitor

289480-64-4

C23H33NaO5

C23H33O5Na