ChemicalBook > CAS DataBase List > Treprostinil Sodium

Treprostinil Sodium

Product Name
Treprostinil Sodium
CAS No.
289480-64-4
Chemical Name
Treprostinil Sodium
Synonyms
Troprostil sodium;UT 15 (pharMaceutical);Treprostinil Sodium API;Treprostinil sodium salt;Treprostinil Sodium (UT-15);Treprostinil sodium (LRX15);289480-64-4 Treprostinil Sodium;Prostaglandin Receptor,UT15,Treprostinil Sodium,inhibit,Treprostinil,UT 15,Inhibitor;2-(((1R,2R,3aS,9aS)-2-Hydroxy-1-((S)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl)oxy)acetic acid, sodium salt;Treprostinil 13C2 D1 Sodium SaltQ: What is Treprostinil 13C2 D1 Sodium Salt Q: What is the CAS Number of Treprostinil 13C2 D1 Sodium Salt Q: What is the storage condition of Treprostinil 13C2 D1 Sodium Salt Q: What are the applications of Treprostinil 13C2 D1 Sodium Salt
CBNumber
CB32460050
Molecular Formula
C23H35NaO5
Formula Weight
414.52
MOL File
289480-64-4.mol
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Treprostinil Sodium Property

storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO : ≥ 26 mg/mL (63.03 mM)
form 
solid
color 
White
InChIKey
XUACDQZEUSYNGG-DJYDVLTONA-N
SMILES
C([C@H]1[C@@H](C[C@]2([H])CC3=C(C=CC=C3C[C@]12[H])OCC(=O)O)O)C[C@@H](O)CCCCC.[NaH] |&1:1,2,4,14,23,r|
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Safety

HS Code 
2918999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-6170
Product name
Treprostinilsodium
Purity
>98.0%
Packaging
1mg
Price
$84
Updated
2021/12/16
Apolloscientific
Product number
BISN0021
Product name
TreprostinilSodium
Purity
97%
Packaging
1mg
Price
$116
Updated
2021/12/16
AK Scientific
Product number
Y0243
Product name
Treprostinilsodium
Packaging
5mg
Price
$196
Updated
2021/12/16
ChemScene
Product number
CS-6170
Product name
Treprostinilsodium
Purity
>98.0%
Packaging
5mg
Price
$264
Updated
2021/12/16
Apolloscientific
Product number
BISN0021
Product name
TreprostinilSodium
Purity
97%
Packaging
5mg
Price
$319
Updated
2021/12/16
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Treprostinil Sodium Chemical Properties,Usage,Production

Description

Treprostinil sodium is a chemically stable prostacyclin analogue that shares at least some of the pharmacologic actions of epoprostenol. The sodium salt of treprostinil is currently approved for the treatment of PAH for either parenteral (Remodulin) or inhaled (Tyvaso) routes of administration. Acute hemodynamic effects with treprostinil are similar to those observed with intravenous epoprostenol in patients with IPAH; however, treprostinil is stable at room temperature and neutral pH and has a longer half-life, 2–3 hours, when administered subcutaneously. Like epoprostenol, treprostinil is infused continuously by a portable pump and can be administered subcutaneously or intravenously. Treprostinil was approved in 2002 for subcutaneous infusion and in 2004 for intravenous injection[1].

Uses

Treprostinil sodium is a potent agonist of DP1, EP2 and IP receptors with Ki 4.4 nM, 3.6 nM and 32 nM, respectively.

Definition

ChEBI: Treprostinil sodium is an organic sodium salt. It contains a treprostinil.

References

[1] Zhi-Cheng Jing. “Efficacy and safety of oral treprostinil monotherapy for the treatment of pulmonary arterial hypertension: a randomized, controlled trial.” Circulation 127 5 (2013): 624–33.

Treprostinil Sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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Treprostinil Sodium Suppliers

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View Lastest Price from Treprostinil Sodium manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
treprostinil sodium 289480-64-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26
Career Henan Chemical Co
Product
REMODULIN 289480-64-4
Price
US $6.60/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg -1000kg
Release date
2020-01-02

289480-64-4, Treprostinil SodiumRelated Search:

REMODULIN 2-[[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[g]naphthalen-5-yl]oxy]acetic acid,2-(2-hydroxyethylamino)ethanol 2,3-DIMETHYLPHENOXYACETIC ACID REMODULIN

  • Treprostinil Sodium API
  • Treprostinil Sodium (UT-15)
  • UT 15 (pharMaceutical)
  • Treprostinil sodium salt
  • 289480-64-4 Treprostinil Sodium
  • Treprostinil sodium (LRX15)
  • Treprostinil 13C2 D1 Sodium SaltQ: What is Treprostinil 13C2 D1 Sodium Salt Q: What is the CAS Number of Treprostinil 13C2 D1 Sodium Salt Q: What is the storage condition of Treprostinil 13C2 D1 Sodium Salt Q: What are the applications of Treprostinil 13C2 D1 Sodium Salt
  • 2-(((1R,2R,3aS,9aS)-2-Hydroxy-1-((S)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl)oxy)acetic acid, sodium salt
  • Troprostil sodium
  • Prostaglandin Receptor,UT15,Treprostinil Sodium,inhibit,Treprostinil,UT 15,Inhibitor
  • 289480-64-4
  • C23H33NaO5
  • C23H33O5Na