ChemicalBook > CAS DataBase List > Slv320

Slv320

Product Name
Slv320
CAS No.
251945-92-3
Chemical Name
Slv320
Synonyms
Slv320;SC-204288;Derenofylline;SLV320 >=98% (HPLC);SLV320; SLV-320; SLV 320; DERENOFYLLINE;4-[(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol;4-[(2-phenyl-7H-pyrrolo[2， 3-d]pyrimidin-4-yl)amino]cyclohexan-1-ol;(1R,4R)-4-(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexanol;trans-4-[(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol;Cyclohexanol, 4-[(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-, trans-
CBNumber
CB32492503
Molecular Formula
C18H20N4O
Formula Weight
308.38
MOL File
251945-92-3.mol
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Slv320 Property

Boiling point:
532.3±60.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
Soluble to 100 mM in DMSO and to 50 mM in ethanol
form 
Powder
pka
15.15±0.40(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27666
Product name
Derenofylline
Packaging
5mg
Price
$92
Updated
2024/03/01
Cayman Chemical
Product number
27666
Product name
Derenofylline
Packaging
25mg
Price
$371
Updated
2024/03/01
Cayman Chemical
Product number
27666
Product name
Derenofylline
Packaging
1mg
Price
$34
Updated
2024/03/01
Cayman Chemical
Product number
27666
Product name
Derenofylline
Packaging
10mg
Price
$166
Updated
2024/03/01
Tocris
Product number
3344
Product name
SLV320
Purity
≥99%(HPLC)
Packaging
10
Price
$181
Updated
2021/12/16
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Slv320 Chemical Properties,Usage,Production

Description

Derenofylline is an adenosine A1 receptor antagonist (Ki = 1 nM). It is selective for adenosine A1 over A2A, A2B, and A3 receptors (Kis = 398, 3,981, and 200 nM, respectively). It decreases adenosine A1 receptor-mediated adenosine-induced bradycardia in rats (ED50 = 0.49 mg/kg) but reduces A2 receptor-mediated adenosine-induced hypotension by only 44.6% when administered at an intravenous dose of 5 mg/kg. It prevents increases in heart levels of collagen I and III in nephrectomized rats when administered at a dose of 10 mg/kg per day. Derenofylline also reduces relative plaque counts in a Zika virus plaque-forming assay in A549 cells (IC50 = 58.6 nM) in an adenosine A1 receptor-independent manner without inducing cytotoxicity when used at concentrations less than 10 μM.

Uses

SLV 320 is an A1 antagonist.

Slv320 Preparation Products And Raw materials

Raw materials

Preparation Products

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Slv320 Suppliers

China 36 United Kingdom 1 United States 11 USA 1 Global 49
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
4966
Advantage
55
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7296
Advantage
58
Jiangsu aikang biomedical research and development co., LTD
Tel
025-66110311 13155353615
Email
qzhang@aikonchem.com
Country
China
ProdList
15527
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30239
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58

251945-92-3, Slv320Related Search:


  • Cyclohexanol, 4-((2-phenyl-1H-pyrrolo(2,3-D)pyrimidin-4-yl)amino)-, trans-
  • Slv320
  • trans-4-[(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol
  • (1R,4R)-4-(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexanol
  • SC-204288
  • Derenofylline
  • 4-[(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol
  • SLV320; SLV-320; SLV 320; DERENOFYLLINE
  • Cyclohexanol, 4-[(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-, trans-
  • SLV320 >=98% (HPLC)
  • rel-(1r,4r)-4-((2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexan-1-ol
  • Inhibitor,P1 receptor,Derenofylline,Adenosine Receptor,SLV320,fibrosis,uraemic,SLV-320,cardiomyopathy,SLV 320,inhibit,Nephrectomy
  • 4-[(2-phenyl-7H-pyrrolo[2， 3-d]pyrimidin-4-yl)amino]cyclohexan-1-ol
  • 251945-92-3