ChemicalBook > CAS DataBase List > Levemir (tn)
Levemir (tn)
- Product Name
- Levemir (tn)
- CAS No.
- 169148-63-4
- Chemical Name
- Levemir (tn)
- Synonyms
- D04539;Levemir;Levemir (tn);Insulin detemir;Levemir (tn) USP/EP/BP;Insulin detemir (usan/inn);Insulin detemir (genetical recombination);Recombinant Insulin Detemir protein (HEK293);Insulin detemir (genetical recombination) (jan)
- CBNumber
- CB32493560
- Molecular Formula
- C267H402N64O76S6
- Formula Weight
- 5916.82198
- MOL File
- 169148-63-4.mol
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Levemir (tn) Property
- form
- Liquid
- color
- Colorless to light yellow
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Levemir (tn) Chemical Properties,Usage,Production
Uses
Antidiabetic.
in vivo
Insulin Detemir (d-INS) (5 IU/kg; i.p.; once daily; 2 weeks) demonstrates weight-sparing effects compared with other insulin formulations, and shows a intestinal tissues preference, potentially involving the activation of insulin/-catenin/CREB signaling pathways[1].
| Animal Model: | Obese type 2 diabetic db/db mice[1] |
| Dosage: | 5 IU/kg |
| Administration: | Intraperitoneal injection; once daily for 2 weeks |
| Result: | Decreased body weight of the mice after 14-day daily injection of d-INS (5 IU/kg) significantly compared with those injected with the same dose of human Insulin or saline. Induced rapid phosphorylation of protein kinase B (Akt) in the gut L cells of normal mice. |
Levemir (tn) Preparation Products And Raw materials
Raw materials
Preparation Products
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Levemir (tn) Suppliers
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
- 58
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