insulin glargine

Product Name: insulin glargine
CAS No.: 160337-95-1
Chemical Name: insulin glargine
Synonyms: Lantus;Solostar;Insulin, glycyl(A21)-arginyl(B31,B32)-;Unii-2zm8cx04rz;insulin glargine;Insulin Glargine RS;Insulin glargine CRS;Insulin glargine/C1A;Insulin Glargine EP/USP;insulin glargine USP/EP/BP
CBNumber: CB1547528
Molecular Formula: C267H404N72O78S6
Formula Weight: 6062.89026
MOL File: 160337-95-1.mol

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insulin glargine Property

storage temp.: -20°C, Inert atmosphere
solubility: Aqueous Acid (Very Slightly)
form: Liquid
color: White to Off-White
Sequence: A-chain: Gly-Ile-Val-Glu-Gln-Cys-Cys-Thr-Ser-Ile-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Gly; B-chain: Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Thr-Arg-Arg (Disulfide bridge: CysA6-CysA11, CysA7-CysB7, CysA20-CysB19)
CAS DataBase Reference: 160337-95-1

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Safety

HS Code: 2937120000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P314Get medical advice/attention if you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0001544
Product name: Insulin glargine for peak identification
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 3.2 mg
Price: $236
Updated: 2025/07/31

Sigma-Aldrich

Product number: Y0001542
Product name: Insulin glargine
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 15 mg
Price: $225
Updated: 2025/07/31

Sigma-Aldrich

Product number: 1342059
Product name: Insulin glargine
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 15.27MG
Price: $500
Updated: 2025/07/31

Sigma-Aldrich

Product number: Y0001544
Product name: Insulin glargine
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0001544
Price: $220
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1342059
Product name: Insulin glargine
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 15.06mg
Price: $454
Updated: 2022/05/15

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insulin glargine Chemical Properties,Usage,Production

Uses

long-acting basal insulin analogue, helping control the blood sugar level of those with type 1 and type 2 diabetes mellitus. It is an analogue of human insulin made by replacing the asparagine residue at position A21 of the A-chain with glycine and adding

Uses

Insulin Glargine (>90%) is an insulin analogue used in the treatment of adults with type 1 or type 2 diabetes.

brand name

Lantus (Hoechst Marion Roussel).

Biological Activity

Insulin glargine is an approved long-acting insulin analog used for management of Diabetes Type 1 and Type 2. Insulin glargine is a human insulin analog where A-chain asparagine 21 was replaced by glycine and B-chain carboxy terminal was extended by two arginine residues.

in vivo

Insulin glargine (2-12.5 IU/kg; subcutaneous injection; 3-12 months) does not present a carcinogenic risk in rodents^[2].
Insulin glargine (450 mg/kg; subcutaneous injection; 6 months) has an improving effect in a mouse model of diabetes^[3].

Animal Model:	Seven-week-old male db/db mice^[3]
Dosage:	450 mg/kg
Administration:	Subcutaneous injection (s.c.); 6 months
Result:	Significantly improved glucose tolerance. Upregulated pancreatic β-cell functional genes, such as INS1, Pdx1, Pax4 and Pax6.

insulin glargine Preparation Products And Raw materials

Raw materials

Preparation Products

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insulin glargine Suppliers

China 80 India 5 United States 2 Global 87

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160337-95-1, insulin glargineRelated Search:

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insulin glargine

Insulin Glargine EP/USP

A21-Gly-B31-Arg-B32-Arg-insulin

Insulin, glycyl(A21)-arginyl(B31,B32)-

Lantus

Solostar

Solostar [insulin delivery pen]

Unii-2zm8cx04rz

Insulin Glargine, recombinant

Insulin glargine CRS

Insulin Glargine RS

Insulin glargine for peak identification CRS

Insulin glargine United States Pharmacopeia (USP) Reference Standard

insulin glargine USP/EP/BP

Insulin (human),21A-glycine-30Ba-Larginine- 30Bb-L-arginine-

Insulin glargine for peak identification (Y0001544)

Insulin Glargine (15.27 mg) (COLD SHIPMENT REQUIRED)

Insulin glargine/C1A

Research Grade Insulin Glargine

160337-95-1

C267H404N72O78S6