Description Application
ChemicalBook > CAS DataBase List > Argireline

Argireline

Description Application
Product Name
Argireline
CAS No.
616204-22-9
Chemical Name
Argireline
Synonyms
Acetyl Hexapeptide-8;Acetyl Hexapeptide;Reproage;Argreline;Acetylene Hexapeptide-8;Acetyl Hexapeptide-3/Acetyl Hexapeptide-8;AH3P;Akililyn;Akirellin;Argireline
CBNumber
CB41092600
Molecular Formula
C34H60N14O12S
Formula Weight
889
MOL File
616204-22-9.mol
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Argireline Property

Density 
1.54
storage temp. 
-20°C
solubility 
water soluble
solubility 
water soluble
pka
4.43±0.10(Predicted)
form 
lyophilized solid
color 
white
Sequence
Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2
InChI
InChI=1/C34H60N14O12S/c1-17(49)43-20(8-11-25(51)52)29(57)47-22(9-12-26(53)54)31(59)48-23(13-16-61-2)32(60)46-21(7-10-24(35)50)30(58)45-19(6-4-15-42-34(39)40)28(56)44-18(27(36)55)5-3-14-41-33(37)38/h18-23H,3-16H2,1-2H3,(H2,35,50)(H2,36,55)(H,43,49)(H,44,56)(H,45,58)(H,46,60)(H,47,57)(H,48,59)(H,51,52)(H,53,54)(H4,37,38,41)(H4,39,40,42)/t18-,19-,20-,21-,22-,23-/s3
InChIKey
RJZNPROJTJSYLC-LLINQDLYSA-N
SMILES
[C@@H](CCC(=O)N)(NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)C)CCC(=O)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(=O)N)CCCNC(N)=N |&1:0,9,17,26,39,50,r|
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Safety

WGK Germany 
2
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0395
Product name
Ac-EEMQRR-NH2 trifluoroacetate salt
Purity
≥95% (HPLC)
Packaging
1mg
Price
$305
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
COS0000038
Product name
ARGIRELINE
Purity
95.00%
Packaging
1MG
Price
$686
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
COS0000038
Product name
ARGIRELINE
Purity
95.00%
Packaging
5MG
Price
$1830
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
COS0000038
Product name
ARGIRELINE
Purity
95.00%
Packaging
10MG
Price
$3260
Updated
2021/12/16
Crysdot
Product number
CD31001275
Product name
Argireline
Purity
98+%
Packaging
10mg
Price
$152
Updated
2021/12/16
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Argireline Chemical Properties,Usage,Production

Description

Argireline is made up of chains of amino acids. Such chains can affect how our cells work, e.g. relaxing our face muscles. It is derived from the peptide Acetyl hexapeptide-3, a substrate of Botulinum toxin, or more commonly known as Botox.

Application

Botox is a common, anti-wrinkle treatment which is applied using a needle. You may achieve the same anti-aging results with products which contain Argireline. Argireline can help prevent the formation of wrinkles by inhibiting muscle movement in the face. Because of this, Argireline cream is sometimes known as “Botox in a jar.”

Uses

Argireline is an anti-wrinkle peptide. Synthetically produced and considered to be highly effective, clinical studies indicate it can reduce the depth of existing wrinkles. May be incorporated into products marketed as having a topical-BoToX. or “wrinkle-erasing” effect.

benefits

Acetyl Hexapeptide-8 is effectivly reduce various kind of facial wrinkles;Replenish the collagen and polysaccharide, repairthe skin.Winkey patented productin China.It is recommended dosage is 3~10%.

Clinical claims and research

Argireline is a synthetic oligopeptide that emulates the sequence of SNAP-25, a type of SNARE. It has significant skin permeation, interferes with the SNARE ternary complex, and has demonstrated interference with catecholamine release from chromaffin cells. Topical use of 10% argireline resulted in a reduced depth and roughness of periorbital wrinkles in 10 healthy women. One study on 14 volunteers showed that 5% argireline reduced periorbital wrinkles by 32% in 28 days. Most recently, argireline’s efficacy has been measured in 60 Chinese women from a randomized control trial. Its total efficacy was 48.9% compared to 0% in the placebo group, and resulted in significantly decreased wrinkle roughness.

Argireline Preparation Products And Raw materials

Raw materials

Preparation Products

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Argireline Suppliers

Jining Huanju Pharmaceutical Co., Ltd.
Tel
0537-2396602 15315373380
Fax
0537-2396602
Email
1754256732@qq.com
Country
China
ProdList
41
Advantage
55
Spec-Chem Industry Inc.
Tel
025-84523390 13505162978
Email
sc@specchemind.com
Country
China
ProdList
117
Advantage
58
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5501
Advantage
55
Sichuan Jisheng Biopharmaceutical Co.,Ltd.
Tel
+86-0833-2598983 +86-18086877136
Fax
+86-833-2598903
Email
Nyx-peptide@jsjpharm.cn
Country
China
ProdList
309
Advantage
58
Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303 +86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4814
Advantage
58
Shenzhen Readline Biotech CO., LTD.
Tel
0755-26659310 15915457431
Fax
0755-26659310
Email
linkunsheng@szreadline.com
Country
China
ProdList
110
Advantage
58
Hangzhou Go Top Peptide Biotech
Tel
0571-88211921 13735575465
Email
sales1@gotopbio.com
Country
China
ProdList
2890
Advantage
58
BJV(SHENZHEN) BIOTECH LTD
Tel
19006605307
Email
1026972457@qq.com
Country
China
ProdList
77
Advantage
58
Jinan Shunyichang new material Co., LTD
Tel
18865936198 18865936198
Email
limin9361@163.com
Country
China
ProdList
90
Advantage
58
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View Lastest Price from Argireline manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
Argireline 616204-22-9
Price
US $500.00-300.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-23
Shanghai Affida new material science and technology center
Product
Acetyl Hexapeptide-8 616204-22-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99
Supply Ability
10 tons
Release date
2024-04-25
Sinoway Industrial co., ltd.
Product
Argireline (Acetyl Hexapeptide-3) 616204-22-9
Price
US $0.00/Kg/Bag
Min. Order
2Kg/Bag
Purity
98% up by HPLC
Supply Ability
20 tons
Release date
2021-07-29

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