Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide
Benifits for skin- Product Name
- Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide
- CAS No.
- 135679-88-8
- Chemical Name
- Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide
- Synonyms
- Vialox;GPRPA-NH2;NH2-GPRPA-NH2;Vialox USP/EP/BP;Vialox, Pentapeptide-3;Pentaeptide-3/Vialox Peptide;Pentapeptide-3/Vialox Peptide;Vialox Peptide / Pentapeptide-3;Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide;L-Alaninamide, glycyl-L-prolyl-L-arginyl-L-prolyl-
- CBNumber
- CB62489984
- Molecular Formula
- C21H37N9O5
- Formula Weight
- 495.58
- MOL File
- 135679-88-8.mol
Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide Property
- Density
- 1.54
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- form
- Solid
- pka
- 13.59±0.20(Predicted)
- color
- White to off-white
- Sequence
- Gly-Pro-Arg-Pro-Ala-NH2
- InChIKey
- BYWJFRMLHFQWSR-AJNGGQMLSA-N
- SMILES
- C(N)(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)CN
N-Bromosuccinimide Price
- Product number
- AK608086
- Product name
- VialoxPeptide(Pentapeptide-3)
- Purity
- 97%
- Packaging
- 250mg
- Price
- $98
- Updated
- 2021/12/16
- Product number
- AK608086
- Product name
- VialoxPeptide(Pentapeptide-3)
- Purity
- 97%
- Packaging
- 1g
- Price
- $293
- Updated
- 2021/12/16
- Product number
- CM133166
- Product name
- (S)-N-((S)-1-amino-1-oxopropan-2-yl)-1-(glycyl-L-prolyl-L-arginyl)pyrrolidine-2-carboxamide
- Purity
- 97%
- Packaging
- 1g
- Price
- $355
- Updated
- 2021/12/16
- Product number
- CD22004775
- Product name
- VialoxPeptide(Pentapeptide-3)
- Purity
- 97%
- Packaging
- 1g
- Price
- $376
- Updated
- 2021/12/16
- Product number
- CD22004775
- Product name
- VialoxPeptide(Pentapeptide-3)
- Purity
- 97%
- Packaging
- 250mg
- Price
- $151
- Updated
- 2021/12/16
Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide Chemical Properties,Usage,Production
Benifits for skin
Vialox, or Pentapeptide-3, is a synthetic peptide that acts on a different part of the neuromuscular junction. As a competitive antagonist at nicotinic acetylcholine receptors, Vialox prevents the sodium influx required for muscle fibers to depolarize and contract. Within one minute of treatment, muscle contracts can be reduced by up to 71%, and 58% of muscle fibers are still immotile two hours later. Vialox can prevent wrinkles from getting deeper due to muscle contractions. In one study, Vialox used twice a day for 28 days resulted in a nearly 50% reduction in wrinkle depth and roughness. It can be used at concentrations of 0.05%–0.3% to treat facial wrinkles and tighten skin.
Uses
Pentapeptide-3 is a pentapeptide fragment of neurotoxin waglerin-1, it can be extracted from the venom of Temple Viper. Pentapeptide-3 is a competitive antagonist of nicotinic acetylcholine receptors (nAChRs), it can blocks nerves at the post-synaptic membrane. Pentapeptide-3 has anti-aging effects and it can be used together with other cosmetic peptides[1][2].
References
[1] Schagen, S.K. Topical peptide treatments with effective anti-aging results. Cosmetics 4(2), 2017.
[2] Zhmak MN, et al. Peptide inhibitors of nicotinic acetylcholine receptor. WO2014/112902Al, 2017.
Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide Preparation Products And Raw materials
Raw materials
Preparation Products
Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide Suppliers
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View Lastest Price from Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide manufacturers
- Product
- Pentapeptide-3 135679-88-8
- Price
- US $500.00-500.00/kg
- Min. Order
- 1kg
- Purity
- ≥99.00%
- Supply Ability
- 1000000
- Release date
- 2025-10-10
- Product
- Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide 135679-88-8
- Price
- US $2.00-5.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-19
- Product
- Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide 135679-88-8
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 2000000T
- Release date
- 2025-06-10