ChemicalBook > CAS DataBase List > Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide

Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide

Benifits for skin

Product Name: Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide
CAS No.: 135679-88-8
Chemical Name: Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide
Synonyms: Vialox;GPRPA-NH2;NH2-GPRPA-NH2;Vialox USP/EP/BP;Vialox, Pentapeptide-3;Pentaeptide-3/Vialox Peptide;Pentapeptide-3/Vialox Peptide;Vialox Peptide / Pentapeptide-3;Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide;L-Alaninamide, glycyl-L-prolyl-L-arginyl-L-prolyl-
CBNumber: CB62489984
Molecular Formula: C21H37N9O5
Formula Weight: 495.58
MOL File: 135679-88-8.mol

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Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide Property

Density: 1.54
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
form: Solid
pka: 13.59±0.20(Predicted)
color: White to off-white
Sequence: Gly-Pro-Arg-Pro-Ala-NH2
InChIKey: BYWJFRMLHFQWSR-AJNGGQMLSA-N
SMILES: C(N)(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)CN

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Ark Pharm

Product number: AK608086
Product name: VialoxPeptide(Pentapeptide-3)
Purity: 97%
Packaging: 250mg
Price: $98
Updated: 2021/12/16

Ark Pharm

Product number: AK608086
Product name: VialoxPeptide(Pentapeptide-3)
Purity: 97%
Packaging: 1g
Price: $293
Updated: 2021/12/16

Chemenu

Product number: CM133166
Product name: (S)-N-((S)-1-amino-1-oxopropan-2-yl)-1-(glycyl-L-prolyl-L-arginyl)pyrrolidine-2-carboxamide
Purity: 97%
Packaging: 1g
Price: $355
Updated: 2021/12/16

Crysdot

Product number: CD22004775
Product name: VialoxPeptide(Pentapeptide-3)
Purity: 97%
Packaging: 1g
Price: $376
Updated: 2021/12/16

Crysdot

Product number: CD22004775
Product name: VialoxPeptide(Pentapeptide-3)
Purity: 97%
Packaging: 250mg
Price: $151
Updated: 2021/12/16

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Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide Chemical Properties,Usage,Production

Benifits for skin

Vialox, or Pentapeptide-3, is a synthetic peptide that acts on a different part of the neuromuscular junction. As a competitive antagonist at nicotinic acetylcholine receptors, Vialox prevents the sodium influx required for muscle fibers to depolarize and contract. Within one minute of treatment, muscle contracts can be reduced by up to 71%, and 58% of muscle fibers are still immotile two hours later. Vialox can prevent wrinkles from getting deeper due to muscle contractions. In one study, Vialox used twice a day for 28 days resulted in a nearly 50% reduction in wrinkle depth and roughness. It can be used at concentrations of 0.05%–0.3% to treat facial wrinkles and tighten skin.

Uses

Pentapeptide-3 is a pentapeptide fragment of neurotoxin waglerin-1, it can be extracted from the venom of Temple Viper. Pentapeptide-3 is a competitive antagonist of nicotinic acetylcholine receptors (nAChRs), it can blocks nerves at the post-synaptic membrane. Pentapeptide-3 has anti-aging effects and it can be used together with other cosmetic peptides[1][2].

References

[1] Schagen, S.K. Topical peptide treatments with effective anti-aging results. Cosmetics 4(2), 2017.
[2] Zhmak MN, et al. Peptide inhibitors of nicotinic acetylcholine receptor. WO2014/112902Al, 2017.

Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide Preparation Products And Raw materials

Raw materials

Preparation Products

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Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide Suppliers

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View Lastest Price from Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide manufacturers

Chengdu Shengnuo Biopharm Co.,Ltd

Product: Pentapeptide-3 135679-88-8
Price: US $500.00-500.00/kg
Min. Order: 1kg
Purity: ≥99.00%
Supply Ability: 1000000
Release date: 2025-10-10

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide 135679-88-8
Price: US $2.00-5.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-19

Anhuyan (Hainan) Biotechnology Co., LTD

Product: Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide 135679-88-8
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 2000000T
Release date: 2025-06-10

135679-88-8, Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamideRelated Search:

Acetyl Tetrapeptide-3 Octapeptide 2 Pentapeptide-25 Aprotinin Palmitoyl Pentapeptide Palmitoyl Tripeptide-5 Acetyl Tetrapeptide-5 Tripeptide-1 (2S)-N2-(1-Oxohexadecyl)-L-lysyl-L-valyl-2,4-diaminobutanoic acid bis(trifluoroacetate) Acetyl Dipeptide-1 cetyl ester MET-GLU-HIS-PHE-ARG-TRP-GLY Rigin Nonapeptide-1 L-Carnosine H-SER-ILE-LYS-VAL-ALA-VAL-OH Palmitoyl Hexapeptide-12 Argireline Dipeptide-2

Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide

Vialox

Vialox Peptide / Pentapeptide-3

GPRPA-NH2

Vialox, Pentapeptide-3

Pentapeptide-3/Vialox Peptide

(2S)-1-(2-aminoacetyl)-N-[(2S)-1-[(2S)-2-[[(2S)-1-amino-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide

L-Alaninamide, glycyl-L-prolyl-L-arginyl-L-prolyl-

Pentaeptide-3/Vialox Peptide

Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide USP/EP/BP

Vialox USP/EP/BP

99.9% Purity L-Alaninamide Powder CAS 135679-88-8 with Best Price From Lab of Biocar

NH2-GPRPA-NH2

Pentapeptide-3, Vialox, Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide

135679-88-8

C21H37N9O5