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Palmitoyl Pentapeptide

Product Name
Palmitoyl Pentapeptide
CAS No.
214047-00-4
Chemical Name
Palmitoyl Pentapeptide
Synonyms
PalMitoyl Pentapeptide-4;PALMITOYL;Palmitoyl Pentapeptide-4/3;Pla-KTTKS;palmitoyl-KTTKS;Matrixyl(PAL-KTTKS);Rejuvenation peptide;Matrixyl 3000 powder;almitoyl pentapeptide;Matrixylacetate, >=95%
CBNumber
CB51214034
Molecular Formula
C39H75N7O10
Formula Weight
802.05
MOL File
214047-00-4.mol
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Palmitoyl Pentapeptide Property

Boiling point:
1120.1±65.0 °C(Predicted)
Density 
1.147
storage temp. 
2-8°C(protect from light)
pka
2.98±0.10(Predicted)
form 
Solid
color 
White to off-white
Sequence
pal-Lys-Thr-Thr-Lys-Ser-OH
InChIKey
WSGCRSMLXFHGRM-DEVHWETNSA-N
SMILES
C(O)(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@H](O)C)NC(=O)[C@H]([C@H](O)C)NC(=O)[C@H](CCCCN)NC(=O)CCCCCCCCCCCCCCC
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AK Scientific
Product number
5022AF
Product name
MatrixylAcetate(PalmitoyPentapeptide)
Packaging
250mg
Price
$309
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
COS0000055
Product name
PALMITOYL PENTAPEPTIDE-4
Purity
95.00%
Packaging
5MG
Price
$502.07
Updated
2021/12/16
AK Scientific
Product number
5022AF
Product name
MatrixylAcetate(PalmitoyPentapeptide)
Packaging
5g
Price
$3069
Updated
2021/12/16
Chemenu
Product number
CM251337
Product name
(2S,5S,8S,11S,14S)-5,14-Bis(4-aminobutyl)-8,11-bis((R)-1-hydroxyethyl)-2-(hydroxymethyl)-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazahentriacontan-1-oicacid
Purity
95%
Packaging
1g
Price
$449
Updated
2021/12/16
Crysdot
Product number
CD22003934
Product name
(2S,5S,8S,11S,14S)-5,14-Bis(4-aminobutyl)-8,11-bis((R)-1-hydroxyethyl)-2-(hydroxymethyl)-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazahentriacontan-1-oicacid
Purity
95+%
Packaging
1g
Price
$475
Updated
2021/12/16
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Palmitoyl Pentapeptide Chemical Properties,Usage,Production

Description

Palmitoyl pentapeptide-4 (formerly called palmitoyl pentapeptide-3) was the fi rst big successful breakthrough peptide ingredient and probably the most commonly used peptide for aging skin. Also known as Matrixyl?, palmitoyl pentatpeptide-4 has been demonstrated to signifi cantly increase collagen synthesis, improving the appearance of wrinkles and sagging of the aging skin. Palmitoyl pentapeptide-4 is basically a sequential piece of a collagen molecule. It is theorized to work by “tricking” the skin into “believing” that too much collagen has been broken down, thereby curbing the production of collagenase, the enzyme that destroys collagen, and stimulating fi broblasts, the cells that produce collagen. The results of using palmitoyl pentapeptide-4 are remarkable, and the performance ingredient does not cause the irritation that can be caused by other antiaging ingredients such as retinol.

Uses

palmitoyl pentapeptide-4 is a skin conditioner. Clinical studies by manufacturers credit it with an ability to promote collagen, elastin, and glycosaminoglycan synthesis. This would result in an ability to restore skin thickness, which diminishes with age, and to reduce the appearance of lines and wrinkles. Palmitoyl pentapeptide4 is a synthetic peptide with serine, threonine, and hexa decanoyl derivatives.
palmitoyl tetrapeptide-7 is formerly known as palmitoyl tetrapeptide3. This peptide appears to improve skin elasticity and firmness. It also hydrates, smoothes, and protects the skin. It can be both obtained from the plant and synthetically derived and is found in a variety of different skin care preparations including eye lotions, moisturizers, and night creams. Palmitoyl tetrapeptide3 appears to act as an anti-inflammatory. This is attributed to its ability to control the secretion of specific chemicals responsible for skin aging (i.e., cytokines and interleukin-6), and hence it may function in a manner similar to the anti-aging hormone, DHeA. Some studies indicate that palmitoyl tetrapeptide-7 may also act as a uV filter.

Uses

Myristoyl pentapeptide-4 is polypeptide used in masks for skin and muscles of face. Also, used in anti-wrinkle and firming facial cleanser.

Definition

palmitoyl pentapeptide-4 is a skin conditioner. Clinical studies by manufacturers credit it with an ability to promote collagen, elastin, and glycosaminoglycan synthesis. This would result in an ability to restore skin thickness, which diminishes with age, and to reduce the appearance of lines and wrinkles. Palmitoyl pentapeptide-4 is a synthetic peptide with serine, threonine, and hexadecanoyl derivatives.

benefits

Palmitoyl Pentapeptide-4 is effectivly reduce various kind of facial wrinkles;Replenish the collagen and polysaccharide, repairthe skin.Winkey patented productin China.It is recommended dosage is 3~10%.

benefits

Palmitoyl pentapeptide-4 was the first peptide to be widely used in products for aging skin. It stimulates collagen and reduces the production of collagenase, the enzyme that breaks down collagen in photoaging skin.
Palmitoyl pentapeptide-4 boost tissue regeneration, activate production of collagen, sucrose osamine and hyaluronic acid,widely used on the long-lasting aging formula. Its recommended dosage is 3~8%.

Mechanism of action

Palmitoyl Pentapeptide appears to work by increasing collagen production, stimulating collagen, elastin, and hyaluronic acid growth, increasing the skin's moisture content and retention, which helps reduce the appearance of fine lines and wrinkles on the skin's surface. Pentapeptide is equivalent to intimate integration with the skin, changing the skin ecology and cell repair, and playing the role of intracellular hormones and enzymes.

Properties and Applications

Cosmetic polypeptides can penetrate the dermis to increase the level of collagen and reverse the aging process of the skin through rebuilding from inside to outside.
Cosmetic pentapeptide(Palmitoyl Pentapeptide) is also a cosmetic polypeptide. The prototype of the polypeptide is palmitic acid pentapeptide, commonly known as the five peptides, being able to simulate the paralysis effect of botulinum toxin. It is a short peptide fragment consisting of five amino acids formed by peptide bonds with its structure being similar to the protein. However, the protein has a longer peptide chain, usually consisting of hundreds of amino acids. Based on the differences of the number of amino acids, these polypeptides are divided into dipeptides (including two amino acids), tripeptides (including three amino acids), tetrapeptides (including four amino acids), etc. Because of the different categories of amino acids contained, both dipeptides and tripeptides have different varieties. At the same time, even with the same number of amino acids, the dipeptides will still have different varieties due to the different sort order of the amino acid. This leads to a number of peptides with a variety of roles and names. The pentapeptide is composed of six amino acids (Pal palmitic acid, Lys-lysine, Thr-threonine, Thr-threonine, Lys-lysine and Ser-serine).
The Palmitoyl Pentapeptide is actually the C-terminal fragment of Collagen I, having an effect being similar to that of the laser surgery. It can stimulate the growth of collagen, stretch fibers and hyaluronic acid, improve skin moisture and the degree of locking water, increase skin thickness and reduce the microgroove; at the same time, addition of a long chain of fatty acids (palmitic acid) can increase the absorption effect. Compared with the laser surgery, the five-peptides is equivalent to intimate fusion with the skin, changing the skin ecology and cell repair, further playing the role of intracellular hormones and enzymes.

Palmitoyl Pentapeptide Preparation Products And Raw materials

Raw materials

Preparation Products

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Palmitoyl Pentapeptide Suppliers

Phygene
Tel
18059081430
Email
2070812664@qq.com
Country
China
ProdList
1232
Advantage
58
Lavem Chine Pharm Company
Tel
28-86066080 18280039962
Fax
86-28-8527-5264
Email
sales@lavemc.com
Country
China
ProdList
214
Advantage
67
Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5501
Advantage
55
Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303 +86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4840
Advantage
58
Spec-Chem Industry Inc.
Tel
025-84523390 13505162978
Email
sc@specchemind.com
Country
China
ProdList
117
Advantage
58
Nanjing Yuanpeptide Biotech Co.,Ltd.
Tel
18168071971
Email
support@yuan-peptide.com
Country
China
ProdList
2979
Advantage
58
Chengdu Shengnuo Biological Peptide Technology Co.,Ltd
Tel
028-88368562
Email
liweidan@snbiopharm.com
Country
China
ProdList
27
Advantage
58
Shandong Jitai Biotech Co., Ltd
Tel
18366132549
Email
372278065@qq.com
Country
China
ProdList
30
Advantage
58
Alabiochem Tech.Co., Ltd.
Tel
0512-58900862 400-0707518
Fax
0086-512-56765862
Email
sales@alabiochem.com
Country
China
ProdList
995
Advantage
59
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
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View Lastest Price from Palmitoyl Pentapeptide manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Palmitoyl Pentapeptide-4 214047-00-4
Price
US $180.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-04-23
Sinoway Industrial co., ltd.
Product
Matrixyl (Palmitoyl Pentapeptide-4) 214047-00-4
Price
US $0.00-0.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
98% up by HPLC
Supply Ability
20 tons
Release date
2024-06-27
Hebei Longbang Technology Co., Ltd
Product
Palmitoyl Pentapeptide 214047-00-4
Price
US $6.00/kg
Min. Order
1kg
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-05-22

214047-00-4, Palmitoyl PentapeptideRelated Search:


  • L-Serine, N2-(1-oxohexadecyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-
  • Matrixyl(PAL-KTTKS)
  • Pal-Lys-Thr-Thr-Lys-Ser-OH
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  • Palmitoyl Pentapeptide-3/Matrixyl
  • palmitoyl-KTTKS
  • Rejuvenation peptide
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  • PALMITOYL
  • Matrixyl Acetate / Palmitoyl Pentapeptide-3
  • N2-(1-oxohexadecyl)-L-lysyl-L-threonyl-L-threonyl-L-lysyl-
  • Matrixyl Acetate / Palmitoyl Pentapeptide-3/4
  • Palmitoyl Pentapeptide-4, palmitoyl pentapeptide-3, Matrixyl, Pal-KTTKS
  • (2S,5S,8S,11S,14S)-5,14-Bis(4-aminobutyl)-8,11-bis((R)-1-hydroxyethyl)-2-(hydroxymethyl)-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazahentriacontan-1-oic acid
  • Palmitoyl pentapeptide-4/Palmitoyl pentapeptide-3
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  • Palmitoyl Pentapeptide-3/4' Matrixxylacetate
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  • Palmitoyl Pentapeptide-3/4, Matrixyl
  • Palmitoyl Pentapeptide-4 TFA salt
  • 214047-00-4
  • C39H75N7O10
  • BEAUTY PEPTIDES
  • Cosmetics beauty peptide
  • APIs
  • 214047-00-4