(D-Ala2)-Leu-Enkephalin
- Product Name
- (D-Ala2)-Leu-Enkephalin
- CAS No.
- 64963-01-5
- Chemical Name
- (D-Ala2)-Leu-Enkephalin
- Synonyms
- (D-ALA2)-LEU-ENKEPHALIN;TYR-D-ALA-GLY-PHE-LEU;D-ALA2-LEU5-ENKEPHALIN;(D-Ala)-Leu-Enkephalin;Tyr-D-Ala-Gly-Phe-Leu-OH;Pentapeptide-3/Leuphasyl;H-TYR-D-ALA-GLY-PHE-LEU-OH;Leuphasyl / Pentapeptide-3;[D-ALA2]-LEUCINE ENKEPHALIN;Leuphasyl / Pentapeptide-18
- CBNumber
- CB3667734
- Molecular Formula
- C29H39N5O7
- Formula Weight
- 569.65
- MOL File
- 64963-01-5.mol
(D-Ala2)-Leu-Enkephalin Property
- Melting point:
- 160-163.5 °C
- Boiling point:
- 991.9±65.0 °C(Predicted)
- Density
- 1.257±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- solubility
- DMF (Slightly), DMSO (Slightly)
- pka
- 3.40±0.10(Predicted)
- form
- Solid
- color
- White to Off-White
- InChI
- InChI=1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)/t18-,22+,23+,24+/m1/s1
- InChIKey
- ZHUJMSMQIPIPTF-JMBSJVKXSA-N
- SMILES
- C(O)(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](CC1=CC=C(O)C=C1)N
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- E5008
- Product name
- [D-Ala2]-Leucine enkephalin
- Purity
- ≥97% (HPLC)
- Packaging
- 5mg
- Price
- $98.9
- Updated
- 2024/03/01
- Product number
- CS-5905
- Product name
- [D-Ala2]-Leucine enkephalin
- Purity
- 99.77%
- Packaging
- 10mg
- Price
- $108
- Updated
- 2021/12/16
- Product number
- FA108766
- Product name
- (D-Ala2)-Leu-Enkephalin H-Tyr-D-Ala-Gly-Phe-Leu-OH
- Packaging
- 25mg
- Price
- $181
- Updated
- 2021/12/16
- Product number
- CS-5905
- Product name
- [D-Ala2]-Leucine enkephalin
- Purity
- 99.77%
- Packaging
- 50mg
- Price
- $420
- Updated
- 2021/12/16
- Product number
- AS112962
- Product name
- [D-Ala2]-Leucine enkephalin
- Purity
- 97%
- Packaging
- 25mg
- Price
- $424
- Updated
- 2021/12/16
(D-Ala2)-Leu-Enkephalin Chemical Properties,Usage,Production
Definition
The leucine-enkephalin (Tyr-Gly-Gly-Phe-Leu, Leu-enk) is a natural endogenous ligand for opiate receptors. Leu-enk is rapidly metabolized in vivo and in vitro[1]. (D-Ala2)-Leu-Enkephalin, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin.
benefits
(D-Ala2)-Leu-Enkephalin is widely distributed in the human body and has essential physiological functions. It has a unique effect on brain cells and can activate sleeping brain cells and have a good recovery effect on the sequelae caused by brain damage. It plays an important role in immune function, including increasing the activity of the immune system, T lymphocytes, NK cells, macrophages, antiviral, and the release of gamma interferon. It can participate in immune regulation by promoting the secretion of endocrine cells by activated immune cells, thereby affecting DNA's gene regulation and expression functions.
References
[1] H. Hasegawa, S. Baba, Y. Shinohara. “Synthesis of [D-Ala2]Leu-enkephalin and [D-Ala2, D-Leu5]Leu-enkephalin with high specific tritiated activity in the leucine residue.” Journal of The Chemical Society-perkin Transactions 1 12 1 (1990): 2641–2644.
(D-Ala2)-Leu-Enkephalin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (D-Ala2)-Leu-Enkephalin manufacturers
- Product
- Pentapeptide-18 64963-01-5
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000kg
- Release date
- 2024-03-20
- Product
- Leuphasyl;Pentapeptide-18 64963-01-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99
- Supply Ability
- 10 tons/per week
- Release date
- 2024-04-17
- Product
- Pentapeptide-18 64963-01-5
- Price
- US $1.00/G
- Min. Order
- 1G
- Purity
- 99%
- Supply Ability
- 10000KG
- Release date
- 2024-07-10