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(D-Ala2)-Leu-Enkephalin

Product Name
(D-Ala2)-Leu-Enkephalin
CAS No.
64963-01-5
Chemical Name
(D-Ala2)-Leu-Enkephalin
Synonyms
(D-ALA2)-LEU-ENKEPHALIN;TYR-D-ALA-GLY-PHE-LEU;D-ALA2-LEU5-ENKEPHALIN;(D-Ala)-Leu-Enkephalin;Tyr-D-Ala-Gly-Phe-Leu-OH;Pentapeptide-3/Leuphasyl;H-TYR-D-ALA-GLY-PHE-LEU-OH;Leuphasyl / Pentapeptide-3;[D-ALA2]-LEUCINE ENKEPHALIN;Leuphasyl / Pentapeptide-18
CBNumber
CB3667734
Molecular Formula
C29H39N5O7
Formula Weight
569.65
MOL File
64963-01-5.mol
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(D-Ala2)-Leu-Enkephalin Property

Melting point:
160-163.5 °C
Boiling point:
991.9±65.0 °C(Predicted)
Density 
1.257±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
DMF (Slightly), DMSO (Slightly)
pka
3.40±0.10(Predicted)
form 
Solid
color 
White to Off-White
InChI
InChI=1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)/t18-,22+,23+,24+/m1/s1
InChIKey
ZHUJMSMQIPIPTF-JMBSJVKXSA-N
SMILES
C(O)(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](CC1=CC=C(O)C=C1)N
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E5008
Product name
[D-Ala2]-Leucine enkephalin
Purity
≥97% (HPLC)
Packaging
5mg
Price
$98.9
Updated
2024/03/01
ChemScene
Product number
CS-5905
Product name
[D-Ala2]-Leucine enkephalin
Purity
99.77%
Packaging
10mg
Price
$108
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA108766
Product name
(D-Ala2)-Leu-Enkephalin H-Tyr-D-Ala-Gly-Phe-Leu-OH
Packaging
25mg
Price
$181
Updated
2021/12/16
ChemScene
Product number
CS-5905
Product name
[D-Ala2]-Leucine enkephalin
Purity
99.77%
Packaging
50mg
Price
$420
Updated
2021/12/16
Activate Scientific
Product number
AS112962
Product name
[D-Ala2]-Leucine enkephalin
Purity
97%
Packaging
25mg
Price
$424
Updated
2021/12/16
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(D-Ala2)-Leu-Enkephalin Chemical Properties,Usage,Production

Definition

The leucine-enkephalin (Tyr-Gly-Gly-Phe-Leu, Leu-enk) is a natural endogenous ligand for opiate receptors. Leu-enk is rapidly metabolized in vivo and in vitro[1]. (D-Ala2)-Leu-Enkephalin, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin.

benefits

(D-Ala2)-Leu-Enkephalin is widely distributed in the human body and has essential physiological functions. It has a unique effect on brain cells and can activate sleeping brain cells and have a good recovery effect on the sequelae caused by brain damage. It plays an important role in immune function, including increasing the activity of the immune system, T lymphocytes, NK cells, macrophages, antiviral, and the release of gamma interferon. It can participate in immune regulation by promoting the secretion of endocrine cells by activated immune cells, thereby affecting DNA's gene regulation and expression functions.

References

[1] H. Hasegawa, S. Baba, Y. Shinohara. “Synthesis of [D-Ala2]Leu-enkephalin and [D-Ala2, D-Leu5]Leu-enkephalin with high specific tritiated activity in the leucine residue.” Journal of The Chemical Society-perkin Transactions 1 12 1 (1990): 2641–2644.

(D-Ala2)-Leu-Enkephalin Preparation Products And Raw materials

Raw materials

Preparation Products

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(D-Ala2)-Leu-Enkephalin Suppliers

Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5501
Advantage
55
Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303 +86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4847
Advantage
58
Hangzhou Go Top Peptide Biotech
Tel
0571-88211921 13355716090
Email
Sales@gotopbio.com
Country
China
ProdList
2857
Advantage
58
Shenzhen JYMed Technology Co., Ltd.
Tel
755-755-26612112 15013529272;
Fax
+86 (755) 8635-0488
Email
jymed@jymedtech.com
Country
China
ProdList
81
Advantage
58
Hubei Zhaoke BIO-CHEMICAL Co., Ltd.
Tel
18271904430
Email
1070737105@qq.com
Country
China
ProdList
217
Advantage
58
Alabiochem Tech.Co., Ltd.
Tel
0512-58900862 400-0707518
Fax
0086-512-56765862
Email
sales@alabiochem.com
Country
China
ProdList
995
Advantage
59
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Cellmano Biotech Limited
Tel
0551-65326643 18156095617
Fax
0551-65326641
Email
info@cellmano.com
Country
China
ProdList
1011
Advantage
55
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View Lastest Price from (D-Ala2)-Leu-Enkephalin manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
Pentapeptide-18 64963-01-5
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000kg
Release date
2024-03-20
Shanghai Affida new material science and technology center
Product
Leuphasyl;Pentapeptide-18 64963-01-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99
Supply Ability
10 tons/per week
Release date
2024-04-17
Wuhan Haorong Biotechnology Co.,Ltd
Product
Pentapeptide-18 64963-01-5
Price
US $1.00/G
Min. Order
1G
Purity
99%
Supply Ability
10000KG
Release date
2024-07-10

64963-01-5, (D-Ala2)-Leu-EnkephalinRelated Search:


  • H-TYR-D-ALA-GLY-PHE-LEU-OH
  • (D-ALA2)-LEU-ENKEPHALIN
  • D-ALA2-LEU5-ENKEPHALIN
  • [D-ALA2]-LEUCINE ENKEPHALIN
  • TYR-D-ALA-GLY-PHE-LEU
  • N-[N-[N-(N-L-tyrosyl-D-alanyl)glycyl]-L-phenylalanyl]-L-leucine
  • (D-alanine2)leucine enkephalin
  • L-Tyr-D-Ala-Gly-L-Phe-L-Leu-OH
  • (D-Ala2)-Leu-Enkephalin H-Tyr-D-Ala-Gly-Phe-Leu-OH
  • (D-Ala)-Leu-Enkephalin
  • [D-ALA2]LEUCINE-ENKEPHALIN, >99%
  • [D-Ala2]leucine-enkephalin,Tyr-D-Ala-Gly-Phe-Leu, >99%
  • Tyr-D-Ala-Gly-Phe-Leu-OH
  • 2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
  • 2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenyl-propanoyl]amino]-4-methyl-valeric acid
  • 2-[[2-[2-[2-[[2-azanyl-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]ethanoylamino]-3-phenyl-propanoyl]amino]-4-methyl-pentanoic acid
  • [D-Ala2]-Leucine enkephalin,Tyr-D-Ala-Gly-Phe-Leu
  • Pentapeptide-3/Leuphasyl
  • L-Tyrosyl-D-alanylglycyl-L-phenylalanyl-L-leucine
  • Tyrosyl-D-alanylglycylphenylalanylleucine
  • Leuphasyl / Pentapeptide-3
  • Leuphasyl / Pentapeptide-18
  • Pentapeptide-18/Leuphasyl with reduce facial muscle
  • L-Leucine, L-tyrosyl-D-alanylglycyl-L-phenylalanyl-
  • 2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoicaci
  • TYR-D-ALA-GLY-PHE-LEU USP/EP/BP
  • Lab Supply High Purity Pentapeptide-18 Powder CAS 64963-01-5 with Best Price
  • 64963-01-5
  • C29H39N5O7
  • Enkephalins
  • Opioid Peptides
  • Peptides
  • Biochemicals and Reagents
  • Amino Acids and Peptides
  • BioChemical