ChemicalBook > CAS DataBase List > (D-Ala2)-Leu-Enkephalin

(D-Ala2)-Leu-Enkephalin

Product Name
(D-Ala2)-Leu-Enkephalin
CAS No.
64963-01-5
Chemical Name
(D-Ala2)-Leu-Enkephalin
Synonyms
(D-ALA2)-LEU-ENKEPHALIN;TYR-D-ALA-GLY-PHE-LEU;D-ALA2-LEU5-ENKEPHALIN;(D-Ala)-Leu-Enkephalin;Pentapeptide-18 Peptide;Tyr-D-Ala-Gly-Phe-Leu-OH;Pentapeptide-3/Leuphasyl;H-TYR-D-ALA-GLY-PHE-LEU-OH;Leuphasyl / Pentapeptide-3;[D-ALA2]-LEUCINE ENKEPHALIN
CBNumber
CB3667734
Molecular Formula
C29H39N5O7
Formula Weight
569.65
MOL File
64963-01-5.mol
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(D-Ala2)-Leu-Enkephalin Property

Melting point:
160-163.5 °C
Boiling point:
991.9±65.0 °C(Predicted)
Density 
1.257±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
DMF (Slightly), DMSO (Slightly)
pka
3.40±0.10(Predicted)
form 
Solid
color 
White to Off-White
InChI
InChI=1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)/t18-,22+,23+,24+/m1/s1
InChIKey
ZHUJMSMQIPIPTF-JMBSJVKXSA-N
SMILES
C(O)(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](CC1=CC=C(O)C=C1)N
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E5008
Product name
[D-Ala2]-Leucine enkephalin
Purity
≥97% (HPLC)
Packaging
5mg
Price
$98.9
Updated
2024/03/01
ChemScene
Product number
CS-5905
Product name
[D-Ala2]-Leucine enkephalin
Purity
99.77%
Packaging
10mg
Price
$108
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA108766
Product name
(D-Ala2)-Leu-Enkephalin H-Tyr-D-Ala-Gly-Phe-Leu-OH
Packaging
25mg
Price
$181
Updated
2021/12/16
ChemScene
Product number
CS-5905
Product name
[D-Ala2]-Leucine enkephalin
Purity
99.77%
Packaging
50mg
Price
$420
Updated
2021/12/16
Activate Scientific
Product number
AS112962
Product name
[D-Ala2]-Leucine enkephalin
Purity
97%
Packaging
25mg
Price
$424
Updated
2021/12/16
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(D-Ala2)-Leu-Enkephalin Chemical Properties,Usage,Production

Definition

The leucine-enkephalin (Tyr-Gly-Gly-Phe-Leu, Leu-enk) is a natural endogenous ligand for opiate receptors. Leu-enk is rapidly metabolized in vivo and in vitro[1]. (D-Ala2)-Leu-Enkephalin, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin.

benefits

(D-Ala2)-Leu-Enkephalin is widely distributed in the human body and has essential physiological functions. It has a unique effect on brain cells and can activate sleeping brain cells and have a good recovery effect on the sequelae caused by brain damage. It plays an important role in immune function, including increasing the activity of the immune system, T lymphocytes, NK cells, macrophages, antiviral, and the release of gamma interferon. It can participate in immune regulation by promoting the secretion of endocrine cells by activated immune cells, thereby affecting DNA's gene regulation and expression functions.

References

[1] H. Hasegawa, S. Baba, Y. Shinohara. “Synthesis of [D-Ala2]Leu-enkephalin and [D-Ala2, D-Leu5]Leu-enkephalin with high specific tritiated activity in the leucine residue.” Journal of The Chemical Society-perkin Transactions 1 12 1 (1990): 2641–2644.

(D-Ala2)-Leu-Enkephalin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (D-Ala2)-Leu-Enkephalin manufacturers

Shandong Huizhihan Supply Chain Co., Ltd
Product
Pentapeptide-18 64963-01-5
Price
US $0.00-0.00/BOX
Min. Order
1BOX
Purity
99%
Supply Ability
20T
Release date
2024-11-05
Shandong Huizhihan Supply Chain Co., Ltd
Product
Pentapeptide-18 Peptide 64963-01-5
Price
US $0.00-0.00/BOX
Min. Order
1BOX
Purity
99%
Supply Ability
20T
Release date
2024-11-06
Shandong Huizhihan Supply Chain Co., Ltd
Product
Pentapeptide-18 64963-01-5
Price
US $0.00-0.00/BOX
Min. Order
1BOX
Purity
99.99%
Supply Ability
1000
Release date
2024-11-06

64963-01-5, (D-Ala2)-Leu-EnkephalinRelated Search:


  • H-TYR-D-ALA-GLY-PHE-LEU-OH
  • (D-ALA2)-LEU-ENKEPHALIN
  • D-ALA2-LEU5-ENKEPHALIN
  • [D-ALA2]-LEUCINE ENKEPHALIN
  • TYR-D-ALA-GLY-PHE-LEU
  • N-[N-[N-(N-L-tyrosyl-D-alanyl)glycyl]-L-phenylalanyl]-L-leucine
  • (D-alanine2)leucine enkephalin
  • L-Tyr-D-Ala-Gly-L-Phe-L-Leu-OH
  • (D-Ala2)-Leu-Enkephalin H-Tyr-D-Ala-Gly-Phe-Leu-OH
  • (D-Ala)-Leu-Enkephalin
  • [D-ALA2]LEUCINE-ENKEPHALIN, >99%
  • [D-Ala2]leucine-enkephalin,Tyr-D-Ala-Gly-Phe-Leu, >99%
  • Tyr-D-Ala-Gly-Phe-Leu-OH
  • 2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
  • 2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenyl-propanoyl]amino]-4-methyl-valeric acid
  • 2-[[2-[2-[2-[[2-azanyl-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]ethanoylamino]-3-phenyl-propanoyl]amino]-4-methyl-pentanoic acid
  • [D-Ala2]-Leucine enkephalin,Tyr-D-Ala-Gly-Phe-Leu
  • Pentapeptide-3/Leuphasyl
  • L-Tyrosyl-D-alanylglycyl-L-phenylalanyl-L-leucine
  • Tyrosyl-D-alanylglycylphenylalanylleucine
  • Leuphasyl / Pentapeptide-3
  • Leuphasyl / Pentapeptide-18
  • Pentapeptide-18/Leuphasyl with reduce facial muscle
  • L-Leucine, L-tyrosyl-D-alanylglycyl-L-phenylalanyl-
  • 2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoicaci
  • TYR-D-ALA-GLY-PHE-LEU USP/EP/BP
  • Lab Supply High Purity Pentapeptide-18 Powder CAS 64963-01-5 with Best Price
  • Pentapeptide-18 Peptide
  • 64963-01-5
  • C29H39N5O7
  • Enkephalins
  • Opioid Peptides
  • Peptides
  • Biochemicals and Reagents
  • Amino Acids and Peptides
  • BioChemical