ChemicalBook > CAS DataBase List > PROTAMINE SULFATE
PROTAMINE SULFATE
- Product Name
- PROTAMINE SULFATE
- CAS No.
- 9009-65-8
- Chemical Name
- PROTAMINE SULFATE
- Synonyms
- Protamin sulfate;ProtaMine sulfates;PROTAMINE SULFATE SALT;Protamine sulfate, Salmine sulfate from salmon sperm;fluxema;usafd-4;SALMINE;dilangio;vasorelax;Ccris 8521
- CBNumber
- CB7727744
- Molecular Formula
- H2O4S
- Formula Weight
- 0
- MOL File
- Mol file
More
Less
PROTAMINE SULFATE Property
- storage temp.
- -20°C
- solubility
- H2O: 10 mg/mL
- form
- amorphous powder
- color
- white
- Water Solubility
- It is sparingly soluble in water.
- Sensitive
- Hygroscopic
- EPA Substance Registry System
- Protamines, sulfates (9009-65-8)
More
Less
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- PHR2610
- Product name
- Protamine sulfate
- Purity
- certified reference material, pharmaceutical secondary standard
- Packaging
- 25MG
- Price
- $261
- Updated
- 2025/07/31
More
Less
PROTAMINE SULFATE Chemical Properties,Usage,Production
Chemical Properties
White or almost white, hygroscopic powder.
Uses
It is suitable for personal care, cosmetic and pharmaceutical applications. It is used widely to reverse the anticoagulant effects of heparin. It acts as a heparin antagonist. It is also a weak anticoagulant. It may be used for the removal of DNA from protein samples or the purification of DNA binding proteins. Protamine sulfate may also be used as an alternative to polybrene in retroviral mediated gene transfer. Protamine sulfate has antibacterial properties and inhibits pepsin activity. Protamine sulfate and other polycations have been shown to inhibit the classical pathway of complement. It neutralizes the anticoagulant activity of heparin, and inhibits turnover of lipoproteins by lipoprotein lipase. The aggregation of erythrocytes in the presence of protamine sulfate, for application to the prediction of MN phenotypes, has been investigated.
Uses
Antidote (to heparin).
in vivo
Protamine sulfate can be used in animal modeling to create cystitis models[5].
Induction of cystitis model[5]
Background
The presence and activity of protamine sulfate may trigger the activation and inflammatory response of the host immune system. These immune responses can lead to the infiltration of inflammatory cells and the production of inflammatory mediators, such as cytokines and interleukins, which can lead to cystitis.
Specific Modeling Methods
Rat: Sprague-Dawley ? female &bull
Administration: 10 mg/mL irrigation in the urinary bladder ? once
Administration: 10 mg/mL irrigation in the urinary bladder ? once
Note
(1) 10 mg/ml protamine sulfate was injected into the rat bladder, and 2 mg/ml LPS was injected 30 minutes later
(2) 5 days later, the experimental animals were put to death under anesthesia, and the bladder was removed for observation.
(2) 5 days later, the experimental animals were put to death under anesthesia, and the bladder was removed for observation.
Modeling Indicators
Physiological indicators: The turbidity, urine volume and the number of red blood cells in the urine of rats were detected.
Molecular changes: The levels of biomarkers IL-6, TNF-α and NF-κB in bladder tissues were detected.
Histological analysis: Hematoxylin and eosin staining were used to detect the number of mast cells in the bladder of rats.
Molecular changes: The levels of biomarkers IL-6, TNF-α and NF-κB in bladder tissues were detected.
Histological analysis: Hematoxylin and eosin staining were used to detect the number of mast cells in the bladder of rats.
Correlated Product(s): LPS (HY-D1056)
Opposite Product(s): /
PROTAMINE SULFATE Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
PROTAMINE SULFATE Suppliers
- Tel
- 021-59178156 17002132182
- 3146474380@qq.com
- Country
- China
- ProdList
- 10000
- Advantage
- 58
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 021-021-021-67601398-809-809-809 15221380277
- Fax
- 021-57711696
- marketing_china@spectrumchemical.com
- Country
- China
- ProdList
- 9658
- Advantage
- 60
- Tel
- 010-56205725
- Fax
- 010-65763397
- waley188@sohu.com
- Country
- China
- ProdList
- 12335
- Advantage
- 58
- Tel
- 400-6206333 13167063860
- Fax
- 021-50323701
- anhua.mao@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- +86-21-65211385-8001 36031160
- Fax
- +86-21-65211385-8004
- sales@shruji.com
- Country
- China
- ProdList
- 3224
- Advantage
- 55
- Tel
- 025-846993838003-8003 18013301590
- Fax
- 025-84699383-8003
- njduly@126.com
- Country
- China
- ProdList
- 3249
- Advantage
- 55
- Tel
- 021-61119791,13386096464
- Fax
- 021-50190009
- bzswkf@foxmail.com
- Country
- China
- ProdList
- 3921
- Advantage
- 50
- Tel
- 400-1166-196 13458535857
- Fax
- QQ：800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 13350
- Advantage
- 58
- Tel
- 15221275939
- Fax
- 021-50706099
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 15873
- Advantage
- 55
More
Less
View Lastest Price from PROTAMINE SULFATE manufacturers
Qiuxian Baitai New Material Co., LTD
- Product
- Protamine Sulfate 9009-65-8
- Price
- US $200.00/KG
- Min. Order
- 100KG
- Purity
- 98%
- Supply Ability
- 50ton/Month
- Release date
- 2021-11-09
9009-65-8, PROTAMINE SULFATERelated Search:
Protocatechualdehyde
SODIUM ORTHOSILICATE
Protoporphyrin IX
Transglutaminase
Prezatide copper acetate
Palmitoyl Pentapeptide
INSULIN ASPART
Argireline
Liraglutide
insulin glargine
Palmitoyl tetrapeptide-7
SALMINE,SALMINE SULFATE,salmine,sulfate(1:1
Isovanillin
Vanillin
SALMINE SULFATE FROM SALMON SPERM