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Talc

Product Name
Talc
CAS No.
14807-96-6
Chemical Name
Talc
Synonyms
TALCUM POWDER;5000S;Talc (Mg3H2(SiO3)4);Magnesium silicate monohydrate;mg3;IT X;TALC;IT 3X;IT 5X;IT FT
CBNumber
CB5853119
Molecular Formula
3MgO.4O2Si.H2O
Formula Weight
379.263
MOL File
14807-96-6.mol
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Talc Property

Melting point:
800 °C
Density 
2.7-2.8
vapor pressure 
0Pa at 25℃
storage temp. 
Sealed in dry,Room Temperature
solubility 
Practically insoluble in water, in ethanol (96 per cent) and in dilute solutions of acids and alkali hydroxides.
form 
Powder/Solid
color 
White to pale gray
Odor
at 100.00?%. odorless
Water Solubility 
Insoluble in water, cold acids, alkalies.
Merck 
14,9037
Exposure limits
ACGIH: TWA 2 mg/m3
NIOSH: IDLH 1000 mg/m3; TWA 2 mg/m3
InChIKey
FPAFDBFIGPHWGO-UHFFFAOYSA-N
LogP
-9.4 at 25℃
IARC
(Vol. 42, Sup 7) 1987, 3 (Vol. 42, Sup 7, 93) 2010, 2B (Vol. 93) 2010
EPA Substance Registry System
Talc (14807-96-6)
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Safety

Hazard Codes 
Xn
Risk Statements 
20-37
Safety Statements 
36
OEB
B
OEL
TWA: 2 mg/m3 (resp)
WGK Germany 
-
RTECS 
WW2710000
TSCA 
Yes
HS Code 
25262020
Hazardous Substances Data
14807-96-6(Hazardous Substances Data)
Toxicity
A finely powdered hydrous magnesium silicate. It is used in a variety of industrial processes and products, including rubber, paints, lubricants, insulating materials, cosmetics, and toiletries, such as baby and dusting powders. Acute inhalation of large quantities of talc, such as infants aspirating a massive amount of powder, has caused death within hours because of drying of the mucous membranes, clogging of the smaller airways, pulmonary edema and pneumonia. Chronic inhalation of talc, such as occurs in talc miners, leads to talcosis (a pneumoconiosis) involving pulmonary fibrosis and pleural sclerosis. Lymph nodes can also be affected. There are suggestions that talc can result in cervical or ovarian cancer although evidence for this is not extensive. Some talc is contaminated with asbestos.
IDLA
1,000 mg/m3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
040318
Product name
Magnesium silicate monohydrate (Talc)
Packaging
100g
Price
$27.5
Updated
2024/03/01
Alfa Aesar
Product number
040318
Product name
Magnesium silicate monohydrate (Talc)
Packaging
2.5kg
Price
$160
Updated
2024/03/01
Alfa Aesar
Product number
040318
Product name
Magnesium silicate monohydrate (Talc)
Packaging
500g
Price
$54.9
Updated
2024/03/01
GFS CHEMICALS
Product number
15553
Product name
TALC
Packaging
2.5kg
Price
$102.03
Updated
2021/12/16
TRC
Product number
T004985
Product name
Talc
Packaging
250g
Price
$120
Updated
2021/12/16
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Talc Chemical Properties,Usage,Production

Description

Soapstone is composed primarily of talc, and has been used for most of recorded history as a carving medium; examples thousands of years old are still extant from Egyptian, Assyrian, and Chinese cultures. The term ‘talc’ was first used in AD 869 to describe minerals that were largely composed of what we now know as talc.

Chemical Properties

Talc is a very fine, white to grayish-white, odorless, impalpable, unctuous, crystalline powder. It adheres readily to the skin and is soft to the touch and free from grittiness.

Chemical Properties

White to almost white micro fine powder, greasy to

Occurrence

Talc is formed under hydrothermal conditions and is a typical mineral of weaker regional metamorphism (regional dynamo-thermometamorphism). It often occurs in association with chlorite, serpentine, or magnesite. The main parent rocks that undergo metamorphic mineral reactions leading to talc formation are either ( magnesite-bearing) siliceous dolomites, or olivine- and/or pyroxene- containing ultrabasics. In ultrabasic rocks, talc is often a product of hydrothermal alteration (autometasomatism). In commercially important deposits, talc occurs in association with tremolite, calcite, quartz, and dolomite, as the product of a more intense regional metamorphism of siliceous dolomites, and with forsterite and anthophyllite due to intense regional metamorphic overprint of ultrabasics. However, talc can also be observed as an authigenic new formation, e.g., in sandy sediments and salt deposits. Other minerals that occur in association with talc include chlorites, mica, actinolite, feldspars, rutile, pyrrhotite, pyrite, magnetite, and hematite. Limonite, a product of the weathering of iron- containing minerals, especially iron- containing ore minerals, can often be found interspersed with talc.

History

Talc, soapstone, and steatite have been used by humans as raw materials since prehistoric times. Molds carved from soapstone were used in the Bronze Age and early Iron Age for casting weapons and tools. In the Mediterranean cultures of the classical period, stone carvings were made from soapstone, and talc was used for treating wounds and in the production of cosmetic powder. In ancient Rome, women used large amounts of powder and rouge. The properties of talc, especially its characteristic greasy feel, were described by Pliny the Elder. The old Arabic word talq, which indicates its greasy nature, gave its name to the mineral. In 1550, Catherin de Medici made it once again fashionable to use facial makeup in the form of powdered talc colored by the addition of pigments, a fashion that found innumerable imitators and has continued without interruption until today.

Uses

Dusting powder, either alone or with starch or boric acid, for medicinal and toilet Preparations; excipient and filler for pills, tablets and for dusting tablet molds; clarifying liquids by filtration. As pigment in paints, varnishes, rubber; filler for paper, rubber, soap; in fireproof and cold-water paints for wood, metal and stone; lubricating molds and machinery; glove and shoe powder; electric and heat insulator.

Uses

Talc is a mineral composed of hydrated magnesium silicate with the chemical formula H2Mg3(SiO3)4 or Mg3Si4O10(OH)2. Talc is used in many industries such as paper making, plastic, paint and coatings, rubber, food, electric cable, pharmaceuticals, cosmetics

Uses

talc adds softness and sliding ability to a cosmetic formulation. It is also used as a bulking and opacifying agent, and as an absorbent in makeup preparations. Talc is an inert powder, generally made from finely ground magnesium silicate, a mineral.

Production Methods

Talc is a naturally occurring hydropolysilicate mineral found in many parts of the world including Australia, China, Italy, India, France, and the USA.
The purity of talc varies depending on the country of origin. For example, Italian types are reported to contain calcium silicate as the contaminant; Indian types contain aluminum and iron oxides; French types contain aluminum oxide; and American types contain calcium carbonate (California), iron oxide (Montana), aluminum and iron oxides (North Carolina), or aluminum oxide (Alabama).
Naturally occurring talc is mined and pulverized before being subjected to flotation processes to remove various impurities such as asbestos (tremolite); carbon; dolomite; iron oxide; and various other magnesium and carbonate minerals. Following this process, the talc is finely powdered, treated with dilute hydrochloric acid, washed with water, and then dried. The processing variables of agglomerated talc strongly influence its physical characteristics.

Definition

Talc, a hydrated magnesium sulfate, is the primary component of most face powders (eye shadows and blushers). In some products, talc makes up to 70% of the formulation. Cosmetic talc should be white, free of asbestos, should have high spreadability or slip, with low coverage. Particle size is acceptable if the material passes through a 200 mesh sieve. Micronized talc is generally lighter and fluffier but less smooth on the skin than regular grades. Typically talc products are sterilized using gamma irradiation. Cosmetic talcs are mined in Italy, France, Norway, India, Spain, China, Egypt, Japan, and the United States. Talc is fairly hydrophobic, although treatments are used to enhance its texture.

General Description

Odorless white to grayish-white very fine crystalline powder (unctuous). Readily adheres to the skin. Nonflammable, noncombustible, and nontoxic.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Talc has low reactivity.

Health Hazard

Pure talc is toxicologically harmless. However, where there are high concentrations of dust in the air, face masks should be worn. If the talc contains detectable amounts of asbestos or asbestos minerals, an MAK value of 2.0 mg/m3 applies. Talc is a nontoxic, inert substance or raw material, but it can contaminate wounds and if inhaled it can cause lung irritations.

Fire Hazard

Literature sources indicate that Talc is nonflammable.

Flammability and Explosibility

Not classified

Pharmaceutical Applications

Talc was once widely used in oral solid dosage formulations as a lubricant and diluent, although today it is less commonly used. However, it is widely used as a dissolution retardant in the development of controlled-release products. Talc is also used as a lubricant in tablet formulations; in a novel powder coating for extended-release pellets; and as an adsorbant.
In topical preparations, talc is used as a dusting powder, although it should not be used to dust surgical gloves. Talc is a natural material; it may therefore frequently contain microorganisms and should be sterilized when used as a dusting powder.
Talc is additionally used to clarify liquids and is also used in cosmetics and food products, mainly for its lubricant properties.

Safety Profile

The talc with less than 1 percent asbestos is regarded as a nuisance dust. Talc with greater percentage of asbestos may be a human carcinogen. A human skin irritant. Prolonged or repeated exposure can produce a form of pulmonary fibrosis (talc pneumoconiosis) which may be due to asbestos content. Questionable carcinogen with experimental tumorigenic data. A common air contaminant.

Safety

Talc is used mainly in tablet and capsule formulations. Talc is not absorbed systemically following oral ingestion and is therefore regarded as an essentially nontoxic material. However, intranasal or intravenous abuse of products containing talc can cause granulomas in body tissues, particularly the lungs. Contamination of wounds or body cavities with talc may also cause granulomas; therefore, it should not be used to dust surgical gloves. Inhalation of talc causes irritation and may cause severe respiratory distress in infants.
Although talc has been extensively investigated for its carcinogenic potential, and it has been suggested that there is an increased risk of ovarian cancer in women using talc, the evidence is inconclusive. However, talc contaminated with asbestos has been proved to be carcinogenic in humans, and asbestos-free grades should therefore be used in pharmaceutical products.
Also, long-term toxic effects of talc contaminated with large quantities of hexachlorophene caused serious irreversible neurotoxicity in infants accidentally exposed to the substance.

Carcinogenicity

In vitro assay of a number of respirable talc specimens of high purity demonstrated a modest but consistent cytotoxicity to macrophages; the investigators conclude that the talcs would be expected to be slightly fibrogenic in vivo.

storage

Talc is a stable material and may be sterilized by heating at 160°C for not less than 1 hour. It may also be sterilized by exposure to ethylene oxide or gamma irradiation.
Talc should be stored in a well-closed container in a cool, dry place.

Toxicity evaluation

The mechanism by which the talc is toxic is largely physical in its function, impairing organ function by inhibiting necessary movement or transfer of material. Pulmonary responses can occur through production of microemboli and granuloma formation.

Incompatibilities

Incompatible with quaternary ammonium compounds.

Regulatory Status

Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (buccal tablets; oral capsules and tablets; rectal and topical preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

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Talc Suppliers

Guangxi Longsheng Huamei Talc Development Co. Ltd.
Tel
0773-7432265
Email
13818806360@139.com
Country
CHINA
ProdList
1
Advantage
58
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
-W&Y Express Chemical Industry Co., Ltd (ShenYang)
Tel
024-31124838 15840046119
Fax
024-25766157
Email
hxwdonald@wzeti.com
Country
China
ProdList
496
Advantage
58
Hubei Tuobang Chemical Co., Ltd.
Tel
027-59106185 13986192185
Email
1438580077@qq.com
Country
China
ProdList
9972
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8415
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
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View Lastest Price from Talc manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Talc 14807-96-6
Price
US $120.00-65.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-04-28
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Agalite 14807-96-6
Price
US $60.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-05-15
Hebei Weibang Biotechnology Co., Ltd
Product
Talc 14807-96-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-01

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