4,6-Dichloro-5-iodopyrimidine

Product Name: 4,6-Dichloro-5-iodopyrimidine
CAS No.: 1137576-38-5
Chemical Name: 4,6-Dichloro-5-iodopyrimidine
Synonyms: 4,6-Dichloro-5-iodopyrimidine;Pyrimidine, 4,6-dichloro-5-iodo-
CBNumber: CB32499456
Molecular Formula: C4HCl2IN2
Formula Weight: 274.87
MOL File: 1137576-38-5.mol

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4,6-Dichloro-5-iodopyrimidine Property

Melting point:: 134.9-136.5 °C
Boiling point:: 313.9±37.0 °C(Predicted)
Density: 2?+-.0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: -5.65±0.26(Predicted)
Appearance: Yellow to brown Solid
InChI: InChI=1S/C4HCl2IN2/c5-3-2(7)4(6)9-1-8-3/h1H
InChIKey: YKSZLCOPANWXES-UHFFFAOYSA-N
SMILES: C1=NC(Cl)=C(I)C(Cl)=N1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 074797
Product name: 4,6-Dichloro-5-iodopyrimidine
Purity: 95+%
Packaging: 250mg
Price: $70
Updated: 2021/12/16

AK Scientific

Product number: X9065
Product name: 4,6-dichloro-5-iodopyrimidine
Packaging: 250mg
Price: $87
Updated: 2021/12/16

Matrix Scientific

Product number: 074797
Product name: 4,6-Dichloro-5-iodopyrimidine
Purity: 95+%
Packaging: 1g
Price: $280
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0143878
Product name: 4,6-DICHLORO-5-IODOPYRIMIDINE
Purity: 95.00%
Packaging: 250MG
Price: $831.6
Updated: 2021/12/16

Matrix Scientific

Product number: 074797
Product name: 4,6-Dichloro-5-iodopyrimidine
Purity: 95+%
Packaging: 5g
Price: $850
Updated: 2021/12/16

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4,6-Dichloro-5-iodopyrimidine Chemical Properties,Usage,Production

Synthesis

1193-21-1

1137576-38-5

Synthesis of 4,6-dichloro-5-iodopyrimidine (8a): a tetrahydrofuran (THF, 2 mL) solution of 4,6-dichloropyrimidine (149 mg, 1.0 mmol) was added to a solution of TMPZnCl-LiCl (1.3 M in THF, 0.85 mL, 1.1 mmol) at 25 °C. The reaction mixture was stirred at this temperature for 45 min. Subsequently, iodine (I2, 381 mg, 1.5 mmol) was dissolved in anhydrous THF (2 mL) and slowly added dropwise to the reaction system and stirring was continued for 0.5 hr. Upon completion of the reaction, the reaction was quenched with saturated aqueous NaHCO3 and aqueous Na2S2O3 (10 mL) and extracted with ether (3 x 50 mL). The organic phases were combined, dried with anhydrous Na2SO4, filtered and the solvent was concentrated in vacuum. Purification by fast column chromatography (CH2Cl2/n-pentane, 1:4) gave the colorless solid product 8a (227 mg, 83% yield). Melting point: 134.9-136.5 °C. 1H NMR (300 MHz, CDCl3) δ: 8.65 (s, 1H). 13C NMR (75 MHz, CDCl3) δ: 166.6, 156.8, 98.9. m/z (relative abundance) by mass spectrum (70 eV, EI): 274 (100) [M+], 239 (27), 97 (12), 83 (12), 57 (21). Infrared spectra (ATR) ν (cm-1): 2923, 2855, 1900, 1499, 1386, 1341, 1296, 1214, 1080, 1014, 790, 763, 745. high-resolution mass spectrometry (EI) calculated value of C4HCl2IN2 (273.8561): measured value 273.8565.

References

[1] Chemistry - A European Journal, 2009, vol. 15, # 6, p. 1468 - 1477
[2] Organic Letters, 2009, vol. 11, # 8, p. 1837 - 1840
[3] Patent: US2011/288296, 2011, A1. Location in patent: Page/Page column 10

4,6-Dichloro-5-iodopyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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4,6-Dichloro-5-iodopyrimidine Suppliers

China 80 India 2 United States 7 Global 89

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View Lastest Price from 4,6-Dichloro-5-iodopyrimidine manufacturers

Career Henan Chemical Co

Product: 4,6-Dichloro-5-iodopyrimidine 1137576-38-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-09

1137576-38-5, 4,6-Dichloro-5-iodopyrimidineRelated Search:

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4,6-Dichloro-5-iodopyrimidine

Pyrimidine, 4,6-dichloro-5-iodo-

1137576-38-5

Heterocycle-Pyrimidine series