4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine

Product Name: 4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine
CAS No.: 42754-96-1
Chemical Name: 4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine
Synonyms: 4,6-dichloro-2H-pyrazolo[3,4-d]pyrimidine;SKL327;6-Dichloro-1H-pyrazolo[3;4,6-dichloropyrrolo[2,3-d]pyrimidine;4,6-Dichloropyrazolo[3,4-d]pyriMidine;4,6-dichloro-1H-pyrazolo[3,4-d]pP03119ine;4,6-Dichloro-1H-pyrazole[3,4-D]pyriMidine;4,6-DICHLORO-1H-PYRAZOLO[3,4-D]PYRIMIDINE;1H-Pyrazolo[3,4-d]pyrimidine,4,6-dichloro-;4,6-DICHLORO-1H-PYRAZOLO[3,4-D]PYRIMIDINE(RS20012005)
CBNumber: CB21215944
Molecular Formula: C5H2Cl2N4
Formula Weight: 189
MOL File: 42754-96-1.mol

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4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine Property

Melting point:: 145 °C (decomp)
Boiling point:: 251.9±50.0 °C(Predicted)
Density: 2.02±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: solid
pka: 7.90±0.20(Predicted)
color: Off-white to yellow

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45-24/25
RIDADR: UN2811
HazardClass: IRRITANT
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D435865
Product name: 4,6-Dichloropyrazolo[3,4-d]pyrimidine
Packaging: 1g
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD21700
Product name: 4,6-Dichloropyrazolo[3,4-d]pyrimidine
Packaging: 250mg
Price: $50
Updated: 2021/12/16

Matrix Scientific

Product number: 057909
Product name: 4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine
Purity: 95%
Packaging: 1g
Price: $65
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD21700
Product name: 4,6-Dichloropyrazolo[3,4-d]pyrimidine
Packaging: 1g
Price: $125
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-5-1W
Product name: 4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine
Packaging: 1g
Price: $125
Updated: 2021/12/16

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4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine Chemical Properties,Usage,Production

Chemical Properties

Yellow solid

Synthesis

To a solution of 2,4,6-trichloropyrimidine-5-carbaldehyde (19.0 g, 990 mmol) in methanol (300 mL) was added drop-wise a solution of hydrazine monohydrate (4.8 mL) in methanol (80 mL) at 0 °C followed by drop-wise addition of triethylamine (13 mL) in methanol (80 mL) at 0 °C. The mixture was stirred at the same temperature for 30 mm. The solvent was removed, and the residue was purified by flash chromatography to afford 4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine (10.3 g, 62 % yield) as a yellow solid. ‘H NMR (CDC13, 400IVIHz): 11.56 (br, 1H), 8.43 (s, 1H). MS m/z 190.68 [M+1].

4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine Preparation Products And Raw materials

Raw materials

UREA-13C Phosphorus oxychloride Urea 3-Amino-4-pyrazolecarbonitrile Acetic acid Sodium hydroxide N,N-Diethylaniline Sulfuric acid

Preparation Products

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4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine Suppliers

Canada 1 China 203 Germany 1 India 4 United Kingdom 1 United States 16 Global 226

Changzhou Langyi Biomedical Technology Co., Ltd.

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View Lastest Price from 4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidine 42754-96-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2020-05-14

Career Henan Chemical Co

Product: 4,6-DICHLORO-1H-PYRAZOLO[3,4-D]PYRIMIDINE 42754-96-1
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: Customized
Release date: 2018-12-17

42754-96-1, 4,6-Dichloro-1H-pyrazolo[3,4-d]pyrimidineRelated Search:

4,6-Dichloro-2-methylpyrimidine Pyrrolo[3,4-c]pyrazole-5(1H)-carboxylic acid, 4,6-dihydro-, 1,1-dimethylethyl ester 4,6-DICHLOROIMIDAZO[4,5-C]PYRIDINE 4,6-DICHLORO-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE 4,6-Dichloro-5-iodopyrimidine 4,6-DIBROMOPYRIMIDINE 4,6-DIBROMOQUINOLINE 4,6-Dichloroquinazoline 4,6-DICHLORO-2-METHYLQUINAZOLINE 4,6-DICHLOROQUINOLINE 4,6-DICHLOROPYRIDO[3,4-D]PYRIMIDINE ETHYL 4,6-DICHLORO-3-QUINOLINECARBOXYLATE 4,6-dichloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine 4,6-DICHLORO-1H-PYRAZOLO[3,4-D]PYRIMIDINE ethyl 5,7-dichloro-1H-pyrazolo[4,3-d]pyrimidine-3-carboxylate 1-Phenyl-4,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine 1-Methyl-4,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine 2-(TERT-BUTYL)-3,7-DICHLORO-5-(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIMIDINE

4,6-DICHLORO-1H-PYRAZOLO[3,4-D]PYRIMIDINE

4,6-dichloro-2H-pyrazolo[3,4-d]pyrimidine

1H-Pyrazolo[3,4-d]pyrimidine,4,6-dichloro-

4,6-dichloropyrrolo[2,3-d]pyrimidine

4,6-Dichloro-1H-pyrazole[3,4-D]pyriMidine

4,6-Dichloropyrazolo[3,4-d]pyriMidine

6-Dichloro-1H-pyrazolo[3

4,6-dichloro-1H-pyrazolo[3,4-d]pP03119ine

4,6-DICHLORO-1H-PYRAZOLO[3,4-D]PYRIMIDINE(RS20012005)

SKL327

42754-96-1

C5H2N4Cl2

Aromatics

Heterocycles

Building Blocks

Pyrazolo[x,x-y]pyridine

Heterocycle-Pyrimidine series

CHIRAL CHEMICALS