Amifostine Thiol Dihydrochloride

ChemicalBook > CAS DataBase List > Amifostine Thiol Dihydrochloride

Amifostine Thiol Dihydrochloride

Product Name: Amifostine Thiol Dihydrochloride
CAS No.: 14653-77-1
Chemical Name: Amifostine Thiol Dihydrochloride
Synonyms: SKL052;WR-1065 2HCl;AMifostine Thiol;WR-1065 dihydrochloride;Amifostine Impurity 1 DiHCl;Amifostine Impurity 10 DiHCl;Amifostine Thiol Dihydrochloride;Amifostine thiol (hydrochloride);Amifostine Thiol Dihydrochloride (90%);Amifostine Impurity 2（Amifostine Thiol）
CBNumber: CB32502994
Molecular Formula: C5H14N2S
Formula Weight: 134.24306
MOL File: 14653-77-1.mol

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Amifostine Thiol Dihydrochloride Property

Melting point:: 184-186°C
storage temp.: -20°C
solubility: H2O: ≥20mg/mL
form: powder
color: white to off-white
Stability:: Hygroscopic

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Safety

Hazard Codes: Xn
Risk Statements: 22-41
Safety Statements: 26-39-41
WGK Germany: 3
HS Code: 2930909165
Toxicity: mouse,LD50,intraperitoneal,400mg/kg (400mg/kg),European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 24, Pg. 48, 1989.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: W2020
Product name: WR-1065
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $100
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1019428
Product name: Amifostine thiol
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 50mg
Price: $1210
Updated: 2024/03/01

Cayman Chemical

Product number: 18612
Product name: Amifostine thiol (hydrochloride)
Packaging: 5mg
Price: $45
Updated: 2024/03/01

Cayman Chemical

Product number: 18612
Product name: Amifostine thiol (hydrochloride)
Packaging: 10mg
Price: $81
Updated: 2024/03/01

Sigma-Aldrich

Product number: W2020
Product name: WR-1065
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $407
Updated: 2024/03/01

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Amifostine Thiol Dihydrochloride Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A metabolite of Amifostine.

Biochem/physiol Actions

WR-1065 is cytoprotective cell-permeable reactive oxygen species scavenger and p53 activator and re-activator. Recently shown to have antiretroviral activity and an active metabolite of Amifostine which selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy.

storage

Desiccate at -20°C

Amifostine Thiol Dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Amifostine Thiol Dihydrochloride

2-[(3-Aminopropyl)amino]ethanethioldihydrochloride

Amifostine Thiol (50 mg) (2-[(3-aminopropyl)amino]ethanethiol, dihydrochloride)

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2-[(3-aminopropyl)amino]ethane-1-thiol dihydrochloride

Amifostine Impurity 2（Amifostine Thiol）

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Ethanethiol, 2-[(3-aminopropyl)amino]-, hydrochloride (1:2)

Amifostine Thiol Dihydrochloride-d4Q: What is Amifostine Thiol Dihydrochloride-d4 Q: What is the CAS Number of Amifostine Thiol Dihydrochloride-d4

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Amifostine thiol (hydrochloride)

Amifostine Impurity 1 DiHCl

Amifostine Impurity 10 DiHCl

Amifostine Thiol (50 mg) (Ethanethiol, 2-[(3-aminopropyl)amino]-, dihydrochloride)

14653-77-1

C5H16Cl2N2S

C5H14N2S2HCl

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