Di(N-succinimidyl) adipate

Product Name: Di(N-succinimidyl) adipate
CAS No.: 59156-70-6
Chemical Name: Di(N-succinimidyl) adipate
Synonyms: bis(2,5-dioxopyrrolidin-1-yl) adipate;RG 00/265;di-Succinimidyl) adipate;Disuccinimidyl Adipate;Di(N-succinimidyl) adipate;Bis-N-Hydroxysuccinimidyl adipate;bis(2,5-dioxopyrrolidin-1-yl) hexanedioate;Adipic acid bis-(N-hydroxysuccinimide) ester;Hexanedioic acid 1,6-bis(2,5-dioxo-1-pyrrolidinyl) ester
CBNumber: CB32507409
Molecular Formula: C14H16N2O8
Formula Weight: 340.29
MOL File: 59156-70-6.mol

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Di(N-succinimidyl) adipate Property

Melting point:: 163-164℃ (ethanol acetonitrile )
Boiling point:: 495.3±55.0 °C(Predicted)
Density: 1.48±0.1 g/cm3 (20 ºC 760 Torr)
storage temp.: Storage temp. -20°C
solubility: Soluble in DMSO, DMF, Acetonitrile
form: Solid
color: White to off-white
InChI: InChI=1S/C14H16N2O8/c17-9-5-6-10(18)15(9)23-13(21)3-1-2-4-14(22)24-16-11(19)7-8-12(16)20/h1-8H2
InChIKey: LZZXZDMVRZJZST-UHFFFAOYSA-N
SMILES: C(ON1C(=O)CCC1=O)(=O)CCCCC(ON1C(=O)CCC1=O)=O

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: D494005
Product name: Di(N-succinimidyl)Adipate
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD44893
Product name: Di(N-succinimidyl) adipate
Packaging: 50mg
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD44893
Product name: Di(N-succinimidyl) adipate
Packaging: 100mg
Price: $80
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD44893
Product name: Di(N-succinimidyl) adipate
Packaging: 250mg
Price: $160
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD44893
Product name: Di(N-succinimidyl) adipate
Packaging: 500mg
Price: $250
Updated: 2021/12/16

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Di(N-succinimidyl) adipate Chemical Properties,Usage,Production

Description

Di(N-succinimidyl)adipate contains two NHS ester groups which can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Uses

Di(N-succinimidyl)adipate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

Alkyl-Chain

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Di(N-succinimidyl) adipate Preparation Products And Raw materials

Raw materials

Preparation Products

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Di(N-succinimidyl) adipate Suppliers

China 71 Germany 1 United Kingdom 1 United States 7 Global 80

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View Lastest Price from Di(N-succinimidyl) adipate manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: Di(N-succinimidyl) adipate 59156-70-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-09-20

Xian confluore Biological Technology Co., Ltd.

Product: Di(N-succinimidyl)adipate 59156-70-6
Price: US $0.00/g
Min. Order: 10g
Purity: >95.00%
Supply Ability: 10g
Release date: 2024-03-30

59156-70-6, Di(N-succinimidyl) adipateRelated Search:

bis(2,5-dioxopyrrolidin-1-yl) 2,2'-disulfanediyldiacetate DISUCCINIMIDYL SUCCINATE Heptanedioic acid 1,7-bis(2,5-dioxo-1-pyrrolidinyl) ester DISUCCINIMIDYL SEBACATE NA TOLUENE-4-SULFONIC ACID OXETAN-3-YL ESTER alpha, oMega-DisucciniMidyl triethylene glycol Bis(NHS)PEG5 alpha, oMega-DisucciniMidyl diethylene glycol

Di(N-succinimidyl) adipate

Bis-N-Hydroxysuccinimidyl adipate

Hexanedioic acid 1,6-bis(2,5-dioxo-1-pyrrolidinyl) ester

RG 00/265

2,5-Pyrrolidinedione, 1,1'-[(1,6-dioxo-1,6-hexanediyl)bis(oxy)]bis-

bis(2,5-dioxopyrrolidin-1-yl) adipate

bis(2,5-dioxopyrrolidin-1-yl) hexanedioate

Adipic acid bis-(N-hydroxysuccinimide) ester

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Succinimidyl) adipate

59156-70-6