ChemicalBook > CAS DataBase List > (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
- Product Name
- (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
- CAS No.
- 80751-65-1
- Chemical Name
- (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
- Synonyms
- Cl-apb;Chloro-AP;SK&F 82958;SKF82958 HBr;SKF82958,SKF 82958;6H-Benzo[cd]pyren-7-one;(±)-SKF 82958;CHLORO-APB;(+/-)-SKF-82958 HYDROBROMIDE;(+/-)-Chloro-apbhydrobromide;(+/-)-CHLORO-APB HYDROBROMIDE
- CBNumber
- CB3251102
- Molecular Formula
- C19H20ClNO2
- Formula Weight
- 329.82
- MOL File
- 80751-65-1.mol
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(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Property
- Boiling point:
- 473.7±45.0 °C(Predicted)
- Density
- 1.234±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- H2O: 3.7 mg/mL
- form
- solid
- pka
- 8.73±0.40(Predicted)
- color
- tan
- Water Solubility
- H2O: 3.7mg/mL
aqueous base: unstable
ethanol: soluble
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- C130
- Product name
- Chloro-APB hydrobromide
- Purity
- solid
- Packaging
- 5mg
- Price
- $178
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- C130
- Product name
- Chloro-APB hydrobromide
- Purity
- solid
- Packaging
- 25mg
- Price
- $244.4
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- C130
- Product name
- Chloro-APB hydrobromide
- Purity
- solid
- Packaging
- 100mg
- Price
- $2010
- Updated
- 2023/01/07
TRC
- Product number
- C364438
- Product name
- Chloro-APB hydrobromide
- Packaging
- 10mg
- Price
- $180
- Updated
- 2021/12/16
Usbiological
- Product number
- 466156
- Product name
- SKF 82958 Hydrobromide
- Packaging
- 5mg
- Price
- $355
- Updated
- 2021/12/16
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(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Chemical Properties,Usage,Production
Uses
Chloro-APB hydrobromide has been used to pharmacologically stimulate D1 dopamine receptors and study its influence on locomotor response in fat mass and obesity-associated protein (FTO) deficient dopamine D1 receptor-expressing medium spiny neurons (D1 MSNs) of mice.
Definition
ChEBI: 9-chloro-5-phenyl-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol is a benzazepine.
Biochem/physiol Actions
Chloro-APB hydrobromide, also known as SKF 82958, is a D1 dopamine receptor agonist. D1 receptor agonists prevent and reverse fentanyl-induced respiratory depression, without impairing opioid analgesia, in cats.
(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Suppliers
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80751-65-1, (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDERelated Search:
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3-CHLOROCATECHOL
Dopamine
3-CHLORO-5-METHYLPHENOL
3-CHLORO-4-METHYLPHENOL
Hordenine hydrochloride
N,N-BIS(2-PHENYL-ETHYL)-N-METHYL-AMINE
2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPIN-7-OL
N,beta-Dimethylphenethylamine hydrochloride
[2-(3-CHLORO-PHENYL)-ETHYL]-ETHYL-AMINE
2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINE
N-ISOBUTYL-2-PROPEN-1-AMINE
6-CHLORO-2,3,4,5-TETRAHYDRO-1-(3-METHYLPHENYL)-3-(2-PROPENYL)-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE
(+/-)-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
(+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
[2-(3-CHLORO-PHENYL)-ETHYL]-METHYL-AMINE
ethyl(1-phenylethyl)benzene