(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

Product Name: (+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
CAS No.: 71636-61-8
Chemical Name: (+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
Synonyms: sk&f81297;(±)-6-Chloro-PB;SKF 81297 hydrobromi;SKF 81297 HYDROBROMIDE;(+/-)-SKF-81297 HYDROBROMIDE;(+/-)-6-CHLORO-PB HYDROBROMIDE;(+-)-6-CHLORO-PB HYDROBROMIDE (+-)-SKF-8 1297, HCL;6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;2,3,4,5-Tetrahydro-6-chloro-1-phenyl-1H-3-benzazepine-7,8-diol;6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol
CBNumber: CB0491974
Molecular Formula: C16H17BrClNO2
Formula Weight: 370.67
MOL File: 71636-61-8.mol

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(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Property

storage temp.: Desiccate at +4°C
solubility: H₂O: 1.7 mg/mL
form: solid
color: gray

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S143
Product name: (±)-6-Chloro-PB hydrobromide
Purity: ≥98% (HPLC), solid
Packaging: 25mg
Price: $271
Updated: 2024/03/01

Sigma-Aldrich

Product number: S143
Product name: (±)-6-Chloro-PB hydrobromide
Purity: ≥98% (HPLC), solid
Packaging: 100mg
Price: $803
Updated: 2023/01/07

Tocris

Product number: 1447
Product name: SKF81297hydrobromide
Purity: ≥98%(HPLC)
Packaging: 50
Price: $901
Updated: 2021/12/16

Tocris

Product number: 1447
Product name: SKF81297hydrobromide
Purity: ≥98%(HPLC)
Packaging: 10
Price: $215
Updated: 2021/12/16

Usbiological

Product number: 256680
Product name: SKF 81297 hydrobromide
Packaging: 10mg
Price: $480
Updated: 2021/12/16

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(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Chemical Properties,Usage,Production

Uses

(±)-6-Chloro-PB hydrobromide has been used as a dopamine D1 receptor (Drd1a) agonist to study the role of the drd1a-dopamine receptor inactivation of extracellular signal?regulated protein kinase 1/2 (ERK1/2) in the wild-type and striatum of dopamine-depleted mice. It has also been used as a Drd1a agonist to identify the contribution of D1 (D1R)-like dopamine receptor signaling on learning and memory in Barnes maze in rats.

Definition

ChEBI: 9-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol is a benzazepine.

Biological Activity

Dopamine D 1 -like receptor agonist. Centrally active following systemic administration in vivo .

Biochem/physiol Actions

(+/-)-6-Chloro-PB HBr is a full D1 dopamine receptor agonist.

(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Suppliers

China 7 Europe 1 Germany 2 Japan 1 Switzerland 1 United Kingdom 1 United States 7 Global 20

3B Pharmachem (Wuhan) International Co.,Ltd.

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Sigma-Aldrich

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EMMX Biotechnology LLC

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Shanghai Universal Biotech Co.,Ltd

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TargetMol Chemicals Inc.

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Nantong QuanYi Biotechnology Co., Ltd

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TargetMol Chemicals Inc.

Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Country: United States
ProdList: 19885
Advantage: 58

71636-61-8, (+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDERelated Search:

R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE SKF 83959 HYDROBROMIDE (+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE R(+)-6-CHLORO-7,8-DIHYDROXY-3-METHYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE (R)-6-CHLORO-2,3,4,5-TETRAHYDRO-1-(4-HYDROXYPHENYL)-1H-3-BENZAZEPINE-7,8-DIOL BROMIDE 6-CHLORO-2,3,4,5-TETRAHYDRO-1-(3-METHYLPHENYL)-3-(2-PROPENYL)-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE (+/-)-6-CHLORO-7,8-DIHYDROXY-3-ALLYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

(+/-)-SKF-81297 HYDROBROMIDE

(+/-)-6-CHLORO-PB HYDROBROMIDE

(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

6-CHLORO-2,3,4,5-TETRAHYDRO-1-PHENYL-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE

SKF 81297 HYDROBROMIDE

sk&f81297

(+-)-6-CHLORO-PB HYDROBROMIDE (+-)-SKF-8 1297, HCL

6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepinehydrobromide

2,3,4,5-Tetrahydro-6-chloro-1-phenyl-1H-3-benzazepine-7,8-diol

6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol

1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-

6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol

6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol

(±)-6-Chloro-PB

(±)-SKF-81297 hydrobromide, (±)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide

SKF 81297 hydrobromi

71636-61-8

C16H16ClNO2HBr

Full D1 dopamine receptor agonist.

Dopamine receptor