R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

Product Name: R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
CAS No.: 67287-39-2
Chemical Name: R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
Synonyms: SKF 81297C;SKF-81297 HBr;R(+)-SKF-81297 HYDROBROMIDE;9-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol:hydrobromide;(R)-6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide;R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
CBNumber: CB6294186
Molecular Formula: C16H17BrClNO2
Formula Weight: 370.67
MOL File: 67287-39-2.mol

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R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Property

Melting point:: >256°C (dec.)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: H₂O: 6 mg/mL
form: solid
color: white to off-white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 15067
Product name: (±)-SKF 81297 (hydrobromide)
Purity: ≥98%
Packaging: 5mg
Price: $97
Updated: 2024/03/01

Cayman Chemical

Product number: 15067
Product name: (±)-SKF 81297 (hydrobromide)
Purity: ≥98%
Packaging: 10mg
Price: $145
Updated: 2024/03/01

Cayman Chemical

Product number: 15067
Product name: (±)-SKF 81297 (hydrobromide)
Purity: ≥98%
Packaging: 25mg
Price: $218
Updated: 2024/03/01

TRC

Product number: S550020
Product name: SKF81297C
Packaging: 10mg
Price: $100
Updated: 2021/12/16

ApexBio Technology

Product number: B6744
Product name: SKF81297hydrobromide
Packaging: 25mg
Price: $247
Updated: 2021/12/16

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R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Chemical Properties,Usage,Production

Uses

SKF 81297C is a dopamine D1 agonist (1).

Hazard

A poison.

Biological Activity

skf 81297 hydrobromide is a selective agonist of the dopamine d1-like receptor, with a ki value of 1.9 nm. the dopamine d1-like receptors, consisting of d1 and d5 subtypes, are a subfamily of dopamine receptors that mediate excitatory neurotransmission after binding the endogenous neurotransmitter dopamine. the dopamine d1-like receptors have been implicated in dopaminergic regulation of a variety of fundamental neurophysiologic processes including mood, motivation, cognitive function, as well as motor activity.1. neumeyer jl, kula ns, bergman j, baldessarini rj. receptor affinities of dopamine d1 receptor-selective novel phenylbenzazepines. european journal of pharmacology, 2003, 474(2-3): 137-140.2. undieh as. pharmacology of signaling induced by dopamine d(1)-like receptor activation. pharmacology & therapeutics, 2010, 128(1): 37-60.3. vermeulen rj, drukarch b, sahadat mc, et al. the dopamine d1 agonist skf 81297 and the dopamine d2 agonist ly 171555 act synergistically to stimulate motor behavior of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned parkinsonian rhesus monkeys. movement disorders, 1994, 9(6): 664-672.

storage

+4°C (desiccate)

R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE Suppliers

China 11 Switzerland 1 United Kingdom 1 United States 7 USA 1 Global 21

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67287-39-2, R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDERelated Search:

R(+)-6-CHLORO-7,8-DIHYDROXY-3-METHYL-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE (R)-6-CHLORO-2,3,4,5-TETRAHYDRO-1-(4-HYDROXYPHENYL)-1H-3-BENZAZEPINE-7,8-DIOL BROMIDE 1-PHENYL-2,3,4,5-TETRAHYDRO-1H-BENZAZEPINE (+/-)-SKF-38393 HYDROCHLORIDE (+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPIN-7-OL R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE 2-phenyl-4-azabicyclo[5.4.0]undeca-7,9,11-triene-9,10-diol

R(+)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE

R(+)-SKF-81297 HYDROBROMIDE

(R)-6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide

9-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol:hydrobromide

SKF 81297C

SKF-81297 HBr

67287-39-2