ChemicalBook > CAS DataBase List > Tolbutamide-d9

Tolbutamide-d9

Product Name
Tolbutamide-d9
CAS No.
1219794-57-6
Chemical Name
Tolbutamide-d9
Synonyms
Mobenol-d9;Artozin-d9;Artosin-d9;[2H9]-Tolbutamide;Tolylsulfonylbutylurea-d9;Tolbutamide-d9 Solution, 100ppm;3-(p-Tolyl-4-sulfonyl)-1-butylurea-d9;1-(Butyl-3-(p-tolyl- sulfonyl)urea-d9;N-Butyl-N'-(4-Methylphenylsulfonyl)urea-d9;N-[(ButylaMino-d9)carbonyl]-4-MethylbenzenesulfonaMide
CBNumber
CB32512331
Molecular Formula
C12H18N2O3S
Formula Weight
270.35
MOL File
1219794-57-6.mol
More
Less

Tolbutamide-d9 Property

Melting point:
108-111°C
storage temp. 
Refrigerator
solubility 
DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:1): 0.14 mg/ml
form 
A solid
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
30738
Product name
Tolbutamide-d9
Packaging
1mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
30738
Product name
Tolbutamide-d9
Packaging
10mg
Price
$575
Updated
2024/03/01
Cayman Chemical
Product number
30738
Product name
Tolbutamide-d9
Packaging
5mg
Price
$324
Updated
2024/03/01
TRC
Product number
T535152
Product name
Tolbutamide-d9
Packaging
25mg
Price
$1355
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
D2584
Product name
Tolbutamide-d9(butyl-d9)
Packaging
0.05g
Price
$1700
Updated
2021/12/16
More
Less

Tolbutamide-d9 Chemical Properties,Usage,Production

Description

Tolbutamide-d9 is intended for use as an internal standard for the quantification of tolbutamide by GC- or LC-MS. Tolbutamide is an inhibitor of sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel Kir6.2 (IC50 = 4.9 μM). It is selective for SUR1/Kir6.2 over SUR2A/Kir6.2 and SUR2B/Kir6.2 channels (IC50s = 85 and 88 μM, respectively). Tolbutamide increases glucose-induced insulin secretion and calcium influx in isolated mouse pancreatic islets. In vivo, tolbutamide (80 mg/kg) reduces blood glucose levels in a mouse model of diabetes induced by streptozotocin (STZ; ). Formulations containing tolbutamide have been used in the treatment of type 2 diabetes.

Chemical Properties

White Solid

Uses

Labelled Tolbutamide (T535150). An antidiabetic, used as a hypoglycemic agent in veterinary medicine.

Tolbutamide-d9 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Tolbutamide-d9 Suppliers

Canada 2 China 16 India 2 United States 1 Global 21
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
Email
sales@altasci.com.cn
Country
China
ProdList
4511
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Nanjing Haolv Biotechnology Co.,Ltd
Tel
025-84622273 17361806303
Email
3004208264@qq.com
Country
China
ProdList
3021
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57423
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44807
Advantage
58
ChengDu SinoStandards Bio-Tech Co.,Ltd. ，
Tel
028-83243028 19136088901
Email
sinostandards@163.com
Country
China
ProdList
4985
Advantage
58
Yancheng Tongming Biotechnology Co., Ltd.
Tel
15195160625
Email
2863565288@qq.com
Country
China
ProdList
5192
Advantage
58

1219794-57-6, Tolbutamide-d9Related Search:

TOLAZAMIDE Tolbutamide Impurity 5 4-Carboxytolbutamide Methyl Ester TOLBUTAMIDE Tolbutamide 4-Carboxy Ethyl Ester 4-Hydroxytolbutamide

  • 1-(Butyl-3-(p-tolyl- sulfonyl)urea-d9
  • 3-(p-Tolyl-4-sulfonyl)-1-butylurea-d9
  • Artosin-d9
  • Artozin-d9
  • Mobenol-d9
  • N-[(ButylaMino-d9)carbonyl]-4-MethylbenzenesulfonaMide
  • N-Butyl-N'-(4-Methylphenylsulfonyl)urea-d9
  • Tolylsulfonylbutylurea-d9
  • 1-(4-methylphenyl)sulfonyl-3-(1,1,2,2,3,3,4,4,4-nonadeuteriobutyl)urea
  • Tolbutamide-d9 Solution, 100ppm
  • [2H9]-Tolbutamide
  • N-[(butyl-1,1,2,2,3,3,4,4,4-d9-amino)carbonyl]-4-methyl-benzenesulfonamide
  • 1219794-57-6
  • C12H9D9N2O3S
  • Aromatics
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Pharmaceuticals
  • Sulfur & Selenium Compounds