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Tolbutamide-d9

Product Name
Tolbutamide-d9
CAS No.
1219794-57-6
Chemical Name
Tolbutamide-d9
Synonyms
Mobenol-d9;Artozin-d9;Artosin-d9;[2H9]-Tolbutamide;Tolylsulfonylbutylurea-d9;Tolbutamide-d9 Solution, 100ppm;3-(p-Tolyl-4-sulfonyl)-1-butylurea-d9;1-(Butyl-3-(p-tolyl- sulfonyl)urea-d9;N-Butyl-N'-(4-Methylphenylsulfonyl)urea-d9;N-[(ButylaMino-d9)carbonyl]-4-MethylbenzenesulfonaMide
CBNumber
CB32512331
Molecular Formula
C12H18N2O3S
Formula Weight
270.35
MOL File
1219794-57-6.mol
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Tolbutamide-d9 Property

Melting point:
108-111°C
storage temp. 
Refrigerator
solubility 
DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:1): 0.14 mg/ml
form 
A solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
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N-Bromosuccinimide Price

Cayman Chemical
Product number
30738
Product name
Tolbutamide-d9
Packaging
1mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
30738
Product name
Tolbutamide-d9
Packaging
10mg
Price
$575
Updated
2024/03/01
Cayman Chemical
Product number
30738
Product name
Tolbutamide-d9
Packaging
5mg
Price
$324
Updated
2024/03/01
TRC
Product number
T535152
Product name
Tolbutamide-d9
Packaging
25mg
Price
$1355
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
D2584
Product name
Tolbutamide-d9(butyl-d9)
Packaging
0.05g
Price
$1700
Updated
2021/12/16
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Tolbutamide-d9 Chemical Properties,Usage,Production

Description

Tolbutamide-d9 is intended for use as an internal standard for the quantification of tolbutamide by GC- or LC-MS. Tolbutamide is an inhibitor of sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel Kir6.2 (IC50 = 4.9 μM). It is selective for SUR1/Kir6.2 over SUR2A/Kir6.2 and SUR2B/Kir6.2 channels (IC50s = 85 and 88 μM, respectively). Tolbutamide increases glucose-induced insulin secretion and calcium influx in isolated mouse pancreatic islets. In vivo, tolbutamide (80 mg/kg) reduces blood glucose levels in a mouse model of diabetes induced by streptozotocin (STZ; ). Formulations containing tolbutamide have been used in the treatment of type 2 diabetes.

Chemical Properties

White Solid

Uses

Labelled Tolbutamide (T535150). An antidiabetic, used as a hypoglycemic agent in veterinary medicine.

Tolbutamide-d9 Preparation Products And Raw materials

Raw materials

Preparation Products

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Tolbutamide-d9 Suppliers

Canada 2 China 16 India 2 United States 1 Global 21
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

1219794-57-6, Tolbutamide-d9Related Search:

TOLAZAMIDE Tolbutamide Impurity 5 4-Carboxytolbutamide Methyl Ester TOLBUTAMIDE Tolbutamide 4-Carboxy Ethyl Ester 4-Hydroxytolbutamide

  • 1-(Butyl-3-(p-tolyl- sulfonyl)urea-d9
  • 3-(p-Tolyl-4-sulfonyl)-1-butylurea-d9
  • Artosin-d9
  • Artozin-d9
  • Mobenol-d9
  • N-[(ButylaMino-d9)carbonyl]-4-MethylbenzenesulfonaMide
  • N-Butyl-N'-(4-Methylphenylsulfonyl)urea-d9
  • Tolylsulfonylbutylurea-d9
  • 1-(4-methylphenyl)sulfonyl-3-(1,1,2,2,3,3,4,4,4-nonadeuteriobutyl)urea
  • Tolbutamide-d9 Solution, 100ppm
  • [2H9]-Tolbutamide
  • N-[(butyl-1,1,2,2,3,3,4,4,4-d9-amino)carbonyl]-4-methyl-benzenesulfonamide
  • 1219794-57-6
  • C12H9D9N2O3S
  • Aromatics
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Pharmaceuticals
  • Sulfur & Selenium Compounds