5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol

Product Name: 5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol
CAS No.: 172152-53-3
Chemical Name: 5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol
Synonyms: 5-(1H-pyrrol-1-yl)-1H-benzo[d]iMidazole-2-thiol;Ilaprazole Impurity A;Ilaprazole Intermediate 2;Enavogliflozin Impurity 21;Ilaprazole intermediate P-3;5-Pyrrol-1-yl-1H-benzoimidazole-2-thiol;5-(1H-Pyroll-1-yl)-2-Mercaptobenzimidazole;5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole;5-(1H-purrole-1-yl)-2-marcapto- benzimidazole;5-pyrrol-1-yl-1,3-dihydrobenzimidazole-2-thione
CBNumber: CB32521216
Molecular Formula: C11H9N3S
Formula Weight: 215.27
MOL File: 172152-53-3.mol

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5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol Property

Boiling point:: 381.7±44.0 °C(Predicted)
Density: 1.40
storage temp.: 2-8°C
solubility: DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form: Solid
pka: 9.61±0.30(Predicted)
color: White to Pale Green
InChI: InChI=1S/C11H9N3S/c15-11-12-9-4-3-8(7-10(9)13-11)14-5-1-2-6-14/h1-7H,(H2,12,13,15)
InChIKey: YYXGYVYKGRUILQ-UHFFFAOYSA-N
SMILES: C1(=S)NC2=CC=C(N3C=CC=C3)C=C2N1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: CHM0390405
Product name: 5-(1H-PYRROL-1-YL)-1H-BENZO[D]IMIDAZOLE-2-THIOL
Purity: 95.00%
Packaging: 5MG
Price: $504.94
Updated: 2021/12/16

Chemenu

Product number: CM162085
Product name: 5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole
Purity: 95%
Packaging: 5g
Price: $777
Updated: 2021/12/16

Crysdot

Product number: CD11233680
Product name: 5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol
Purity: 95+%
Packaging: 5g
Price: $831
Updated: 2021/12/16

AccelPharmtech

Product number: A7973
Product name: 1,3-dihydro-5-(1H-pyrrol-1-yl)-2H-Benzimidazole-2-thione
Purity: 97.00%
Packaging: 1G
Price: $1740
Updated: 2021/12/16

AccelPharmtech

Product number: A7973
Product name: 1,3-dihydro-5-(1H-pyrrol-1-yl)-2H-Benzimidazole-2-thione
Purity: 97.00%
Packaging: 5G
Price: $2960
Updated: 2021/12/16

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5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol Chemical Properties,Usage,Production

Uses

5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole is a pharmaceutical intermediate compound used in the synthesis of various drugs such as ilaprazole, gastric and ulcer drugs.

Synthesis

Water (100ml) and anhydrous sodium acetate (16.02g, 0.20mole) were added, and then 2-mercapto-5- aminobenzimidazole (32.27g, 0.20mole),2,5-dimethoxytetrahydrofuran (28.4g, 0.21mole), and acetic acid (100ml) were added. Then, stirring was carried out at 5O℃ for 4 hours. The resultant product was cooled to 50C, and tetrahydrofuran (420ml) was added. The mixture was neutralized with a sodium hydroxide aqueous solution, and water (130ml) was added to carry out layer- separation. Then, an organic layer was washed with a sodium hydroxide aqueous solution. The organic layer was dried by anhydrous magnesium sulfate and concentrated, and then crystallized by ethyl acetate and n-hexane to provide a final compound, that is 5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol. Yield: 35.7g (85%)

5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol Suppliers

China 191 India 6 United Kingdom 1 United States 1 Global 199

Shanghai Qiao Chemical Science Co., Ltd

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View Lastest Price from 5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiol manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole 172152-53-3
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 10 tons
Release date: 2021-08-09

Shaanxi Dideu Medichem Co. Ltd

Product: 5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole 172152-53-3
Price: US $0.10/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000 tons
Release date: 2020-04-24

Zhuhai Hairuide Bioscience and Technology Co., Ltd

Product: 5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole 172152-53-3
Price: US $0.00/KG Ton
Min. Order: 1KG Ton
Purity: 99%+
Supply Ability: 2 tons/month
Release date: 2022-10-09

172152-53-3, 5-(1H-Pyrrol-1-yl)-1H-benzo[d]imidazole-2-thiolRelated Search:

Succinimide

5-(1H-pyrrol-1-yl)-1H-benzo[d]iMidazole-2-thiol

1,3-dihydro-5-(1H-pyrrol-1-yl)-2H-Benzimidazole-2-thione

5-pyrrol-1-yl-1,3-dihydrobenzimidazole-2-thione

5-(1H-Pyrrol-1-yl)-2-mercaptobenzimidazole

2H-Benzimidazole-2-thione, 1,3-dihydro-5-(1H-pyrrol-1-yl)-

5-(1H-purrole-1-yl)-2-marcapto- benzimidazole

Ilaprazole Intermediate 2

5-Pyrrol-1-yl-1H-benzoimidazole-2-thiol

5- (1H pyrrolidine-1-yl) -2-mercaptobenzimidazole

5-(1H-Pyroll-1-yl)-2-Mercaptobenzimidazole

5-(1H-pyrrol-1-yl)-1H-benzo[d]imidazole-2(3H)-thione

Ilaprazole intermediate P-3

Enavogliflozin Impurity 21

Ilaprazole Impurity A

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