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Z-NH-5(ethylene glycol)-acetic acid

Product Name
Z-NH-5(ethylene glycol)-acetic acid
CAS No.
1449390-66-2
Chemical Name
Z-NH-5(ethylene glycol)-acetic acid
Synonyms
CbzNH-P5-CH2CO2H;Z-NH-PEG5-CH2COOH;CBZ-NH-PEG5-CH2COOH;CBZ-NH-PEG5-acetic acid;Z-NH-5(ethylene glycol)-acetic acid;5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester;CbzNH-PEG5-CH2COOH/5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester;inhibit,PROTAC Linkers,Cbz-NH-PEG-5-CH2COOH,Inhibitor,Cbz NH PEG5 CH2COOH,CbzNHPEG5CH2COOH
CBNumber
CB32547012
Molecular Formula
C20H31NO9
Formula Weight
429.46
MOL File
1449390-66-2.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Activate Scientific
Product number
AS107905
Product name
CbzNH-PEG5-CH2COOH
Purity
97%
Packaging
250mg
Price
$283
Updated
2021/12/16
chempep
Product number
280303
Product name
Z-NH-PEG5-CH2COOH
Purity
>=95%
Packaging
1g
Price
$433
Updated
2021/12/16
ChemPep
Product number
280303
Product name
Z-NH-PEG5-CH2COOH
Packaging
5g
Price
$1083
Updated
2021/12/16
purepeg
Product number
4322905
Product name
CBZ-NH-PEG5-CH2COOH
Purity
min.97%
Packaging
1g
Price
$450
Updated
2021/12/16
Acrotein
Product number
B-1093
Product name
CbzNH-PEG5-CH2COOH
Purity
97%
Packaging
1g
Price
$412.5
Updated
2021/12/16
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Z-NH-5(ethylene glycol)-acetic acid Chemical Properties,Usage,Production

Biological Activity

Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Z-NH-5(ethylene glycol)-acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-NH-5(ethylene glycol)-acetic acid Suppliers

ChemPep, Inc.
Tel
+1 (888) 615-9178 / (561) 791-8787
Fax
+1 (561) 791-8728
Email
service@chempep.com
Country
United States
ProdList
2138
Advantage
57
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32080
Advantage
58
9i LLC
Tel
+18039569191
Fax
+13026429191
Email
MWan@NiNeiLab.com
Country
United States
ProdList
418
Advantage
58
PurePEG,LLC
Tel
--
Fax
--
Email
info@purepeg.com
Country
United States
ProdList
697
Advantage
58

1449390-66-2, Z-NH-5(ethylene glycol)-acetic acidRelated Search:


  • Z-NH-5(ethylene glycol)-acetic acid
  • Z-NH-PEG5-CH2COOH
  • CBZ-NH-PEG5-acetic acid
  • CBZ-NH-PEG5-CH2COOH
  • 5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester
  • CbzNH-P5-CH2CO2H
  • inhibit,PROTAC Linkers,Cbz-NH-PEG-5-CH2COOH,Inhibitor,Cbz NH PEG5 CH2COOH,CbzNHPEG5CH2COOH
  • CbzNH-PEG5-CH2COOH/5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(phenylmethyl) ester
  • 1449390-66-2
  • PEGylated Amino Acid