2-(tert-butyldiMethylsilyloxy)ethanaMine

Product Name: 2-(tert-butyldiMethylsilyloxy)ethanaMine
CAS No.: 101711-55-1
Chemical Name: 2-(tert-butyldiMethylsilyloxy)ethanaMine
Synonyms: DK026;DK445;DKFELEX0095;Ethanamine, mono-TMS;2-(t-Butyldimethylsilyloxy)Ethanamine;2-amino-tert-butyldimethylsilyloxyethane;2-(tert-ButyldiMethylsilyloxy)ethylaMine;2-(tert-butyldiMethylsilyloxy)ethanaMine;(2-Aminoethoxy)(tert-butyl)dimethylsilane;Ethanolamine tert-butyldimethylsilyl ether
CBNumber: CB32565625
Molecular Formula: C8H21NOSi
Formula Weight: 175.34
MOL File: 101711-55-1.mol

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2-(tert-butyldiMethylsilyloxy)ethanaMine Property

Boiling point:: 178.4±13.0 °C(Predicted)
Density: 0.849±0.06 g/cm3(Predicted)
refractive index: 1.43
storage temp.: 2-8°C(protect from light)
form: Light Brown Liquid
pka: 8.78±0.10(Predicted)
color: Colorless to Almost colorless
InChI: InChI=1S/C8H21NOSi/c1-8(2,3)11(4,5)10-7-6-9/h6-7,9H2,1-5H3
InChIKey: XDXFUMZONWWODJ-UHFFFAOYSA-N
SMILES: C(N)CO[Si](C(C)(C)C)(C)C

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Safety

HS Code: 2931900090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B5874
Product name: 2-[[tert-Butyl(dimethyl)silyl]oxy]ethylamine
Packaging: 1ML
Price: $49
Updated: 2026/04/30

TCI Chemical

Product number: B5874
Product name: 2-[[tert-Butyl(dimethyl)silyl]oxy]ethylamine
Packaging: 5ML
Price: $156
Updated: 2026/04/30

TRC

Product number: B691205
Product name: 2-(tert-Butyldimethylsilyloxy)ethylamine
Packaging: 1g
Price: $155
Updated: 2021/12/16

TRC

Product number: B691205
Product name: 2-(tert-Butyldimethylsilyloxy)ethylamine
Packaging: 10g
Price: $1230
Updated: 2021/12/16

Matrix Scientific

Product number: 121258
Product name: 2-(tert-Butyldimethylsilyloxy)ethylamine
Purity: 97%
Packaging: 25g
Price: $2240
Updated: 2021/12/16

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2-(tert-butyldiMethylsilyloxy)ethanaMine Chemical Properties,Usage,Production

Chemical Properties

2-(tert-butyldiMethylsilyloxy)ethanaMine is Light Brown Liquid

Uses

2-(tert-butyldiMethylsilyloxy)ethanaMine is used in the preparation of 3-substituted androsterone derivatives.

Synthesis

141-43-5

18162-48-6

101711-55-1

The general procedure for the synthesis of 2-((tert-butyldimethylsilyloxy)ethylamine from 2-aminoethanol and tert-butyldimethylsilyl chloride was as follows: a solution of tert-butyldimethylsilyl chloride (3.6 g, 24 mmol) dissolved in dichloromethane (10 mL) was added slowly and dropwise over a period of 3 minutes to a stirring mixture of 2-aminoethanol (1.22 g, 20 mmol) and imidazole (2.04 g, 30 mmol) in a mixed solution. The reaction mixture was continued to be stirred at room temperature for 1 hour. Subsequently, water (20 mL) was added for quenching and the organic and aqueous phases were separated. The aqueous phase was extracted with dichloromethane (2 x 20 mL), all organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give the light yellow oily product 2-((tert-butyldimethylsilyloxy)ethylamine (3.50 g, 100% yield). The product was confirmed by NMR hydrogen spectrum (400 MHz, CDCl3): δ 3.64 (t, J = 5.0 Hz, 2H), 3.05 (br s, 2H), 2.80 (t, J = 5.0 Hz, 2H), 0.90 (s, 9H), 0.06 (s, 6H); NMR carbon spectrum (100 MHz, CDCl3): δ 64.7, 44.1, 25.9, 18.3, -3.4; mass spectrum (APCI+) showing the molecular ion peak [M + H]+ = 176.6.

References

[1] Journal of Organic Chemistry, 2010, vol. 75, # 17, p. 6023 - 6026
[2] Patent: WO2015/100363, 2015, A1. Location in patent: Page/Page column 43
[3] Patent: US2014/194431, 2014, A1. Location in patent: Paragraph 1044-1045
[4] Angewandte Chemie - International Edition, 2014, vol. 53, # 42, p. 11356 - 11360
[5] Angew. Chem., 2014, vol. 126, # 42, p. 11538 - 11542,5

2-(tert-butyldiMethylsilyloxy)ethanaMine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(tert-butyldiMethylsilyloxy)ethanaMine Suppliers

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View Lastest Price from 2-(tert-butyldiMethylsilyloxy)ethanaMine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 2-(t-Butyldimethylsilyloxy)Ethanamine 101711-55-1
Price: US $1.10-9.90/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 100kg
Release date: 2025-08-18

Career Henan Chemical Co

Product: 2-(tert-butyldiMethylsilyloxy)ethanaMine 101711-55-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 25kg
Release date: 2019-07-11

101711-55-1, 2-(tert-butyldiMethylsilyloxy)ethanaMineRelated Search:

(2-Azidoethoxy)(tert-butyl)diMethylsilane TERT-BUTYLDIMETHYLSILANOL

2-(tert-butyldiMethylsilyloxy)ethanaMine

EthanaMine, 2-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-

2-(tert-ButyldiMethylsilyloxy)ethylaMine

2-(t-Butyldimethylsilyloxy)Ethanamine

(2-Aminoethoxy)(tert-butyl)dimethylsilane

Ethanolamine tert-butyldimethylsilyl ether

[2-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]ethyl]amine

2-(tert-butyl-dimethylsilanyloxy)ethylamine

2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethanamine

Ethanamine, mono-TMS

2-amino-tert-butyldimethylsilyloxyethane

DK026

DK445

2-(Tert-butyl dimethyl sulyloxy)ethanamine

DKFELEX0095

101711-55-1

C8H21NOSi

Miscellaneous Reagents