ChemicalBook > CAS DataBase List > 4SC-201

4SC-201

Product Name
4SC-201
CAS No.
864814-88-0
Chemical Name
4SC-201
Synonyms
CS-304;RAS2410;4SC-201;ResMinostat;ResMinostat(4SC-201);ResMinostat (RAS2410);RESMINOSTAT; 4SC-201; RAS2410;4SC-201(resminostat,BYK408740);RAS2410;4SC-201;RAS 2410;RAS-2410;(E)-3-[1-[4-[(dimethylamino)methyl]phenyl]sulfonylpyrrol-3-yl]-N-hydroxyprop-2-enamide
CBNumber
CB32582958
Molecular Formula
C16H19N3O4S
Formula Weight
349.4
MOL File
864814-88-0.mol
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4SC-201 Property

Density 
1.28±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Powder
pka
8.68±0.23(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ApexBio Technology
Product number
A4108
Product name
Resminostat(RAS2410)
Packaging
5mg
Price
$173
Updated
2021/12/16
ApexBio Technology
Product number
A4108
Product name
Resminostat(RAS2410)
Packaging
10mg
Price
$284
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611518
Product name
Resminostat
Packaging
100mg
Price
$690.2
Updated
2021/12/16
ApexBio Technology
Product number
A4108
Product name
Resminostat(RAS2410)
Packaging
50mg
Price
$1010
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611518
Product name
Resminostat
Packaging
250mg
Price
$1208.7
Updated
2021/12/16
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4SC-201 Chemical Properties,Usage,Production

Uses

Resminostat is an oral histone deacetylase (HDAC) inhibitor. It inhibits proliferation and induces apoptosis in multiple myeloma (MM) cells.

Biological Activity

resminostat, also known as ras2410, is a potent inhibitor of histone deacetylase (hdac) classes i and ii (including hdac1, hdac3 and hdac6) with 50% inhibition concentration ic50 values ranging from 43 to 72 nmol/l. resminostate has the potential to be used for the treatment of multiple myeloma (mm) due to its ability to induce histone h4 hyperacetylation, and apoptosis (ic50 ranging from 2.5 to 3 μmol/l) in mm cells. recent study results have shown that, in mm cell lines, resminostat abrogates cell growth, suppresses proliferation and induce g0/g1 cell cycle arrest as well as interfering with akt signaling pathway by decreasing phosphorylation of 4e-bp1 and p70s6k.mandl-weber s, meinel fg, jankowsky r, oduncu f, schmidmaier r, baumann p. the novel inhibitor of histone deacetylase resminostat (ras2410) inhibits proliferation and induces apoptosis in multiple myeloma (mm) cells. br j haematol. 2010; 149(4):518-528.

4SC-201 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4SC-201 manufacturers

Career Henan Chemical Co
Product
Resminostat 864814-88-0
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2019-12-30

864814-88-0, 4SC-201Related Search:


  • 4SC-201
  • RAS2410
  • ResMinostat(4SC-201)
  • ResMinostat
  • RESMINOSTAT; 4SC-201; RAS2410
  • (E)-3-[1-[[4-[(Dimethylamino)methyl]benzene]sulfonyl]-1H-pyrrol-3-yl]-N-hydroxyacrylamide
  • ResMinostat (RAS2410)
  • (E)-3-[1-[4-[(dimethylamino)methyl]phenyl]sulfonylpyrrol-3-yl]-N-hydroxyprop-2-enamide
  • RAS2410;4SC-201;RAS 2410;RAS-2410
  • CS-304
  • 2-Propenamide, 3-[1-[[4-[(dimethylamino)methyl]phenyl]sulfonyl]-1H-pyrrol-3-yl]-N-hydroxy-, (2E)-
  • (E)-3-[1-[[4-[(Dimethylamino)methyl]benzene]sulfonyl]-1H-pyrrol-3-yl]-N-hydroxyacrylamide Resminostat
  • (E)-3-(1-((4-((Dimethylamino)methyl)phenyl)sulfonyl)-1H-pyrrol-3-yl)-N-hydroxyacrylamide
  • 4SC-201(resminostat,BYK408740)
  • 864814-88-0
  • Inhibitor
  • Inhibitors