4SC-201

ChemicalBook > CAS DataBase List > 4SC-201

Product Name: 4SC-201
CAS No.: 864814-88-0
Chemical Name: 4SC-201
Synonyms: CS-304;RAS2410;4SC-201;ResMinostat;ResMinostat(4SC-201);ResMinostat (RAS2410);RESMINOSTAT; 4SC-201; RAS2410;4SC-201(resminostat,BYK408740);RAS2410;4SC-201;RAS 2410;RAS-2410;(E)-3-[1-[4-[(dimethylamino)methyl]phenyl]sulfonylpyrrol-3-yl]-N-hydroxyprop-2-enamide
CBNumber: CB32582958
Molecular Formula: C16H19N3O4S
Formula Weight: 349.4
MOL File: 864814-88-0.mol

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4SC-201 Property

Density: 1.28±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Powder
pka: 8.68±0.23(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ApexBio Technology

Product number: A4108
Product name: Resminostat(RAS2410)
Packaging: 5mg
Price: $173
Updated: 2021/12/16

ApexBio Technology

Product number: A4108
Product name: Resminostat(RAS2410)
Packaging: 10mg
Price: $284
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611518
Product name: Resminostat
Packaging: 100mg
Price: $690.2
Updated: 2021/12/16

ApexBio Technology

Product number: A4108
Product name: Resminostat(RAS2410)
Packaging: 50mg
Price: $1010
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611518
Product name: Resminostat
Packaging: 250mg
Price: $1208.7
Updated: 2021/12/16

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4SC-201 Chemical Properties,Usage,Production

Uses

Resminostat is an oral histone deacetylase (HDAC) inhibitor. It inhibits proliferation and induces apoptosis in multiple myeloma (MM) cells.

Biological Activity

resminostat, also known as ras2410, is a potent inhibitor of histone deacetylase (hdac) classes i and ii (including hdac1, hdac3 and hdac6) with 50% inhibition concentration ic50 values ranging from 43 to 72 nmol/l. resminostate has the potential to be used for the treatment of multiple myeloma (mm) due to its ability to induce histone h4 hyperacetylation, and apoptosis (ic50 ranging from 2.5 to 3 μmol/l) in mm cells. recent study results have shown that, in mm cell lines, resminostat abrogates cell growth, suppresses proliferation and induce g0/g1 cell cycle arrest as well as interfering with akt signaling pathway by decreasing phosphorylation of 4e-bp1 and p70s6k.mandl-weber s, meinel fg, jankowsky r, oduncu f, schmidmaier r, baumann p. the novel inhibitor of histone deacetylase resminostat (ras2410) inhibits proliferation and induces apoptosis in multiple myeloma (mm) cells. br j haematol. 2010; 149(4):518-528.

4SC-201 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4SC-201 manufacturers

Career Henan Chemical Co

Product: Resminostat 864814-88-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2019-12-30

864814-88-0, 4SC-201Related Search:

ACY-1215 Panobinostat Mocetinostat (MGCD0103) Pracinostat Entinostat CRA-02478

4SC-201

RAS2410

ResMinostat(4SC-201)

ResMinostat

RESMINOSTAT; 4SC-201; RAS2410

(E)-3-[1-[[4-[(Dimethylamino)methyl]benzene]sulfonyl]-1H-pyrrol-3-yl]-N-hydroxyacrylamide

ResMinostat (RAS2410)

(E)-3-[1-[4-[(dimethylamino)methyl]phenyl]sulfonylpyrrol-3-yl]-N-hydroxyprop-2-enamide

RAS2410;4SC-201;RAS 2410;RAS-2410

CS-304

2-Propenamide, 3-[1-[[4-[(dimethylamino)methyl]phenyl]sulfonyl]-1H-pyrrol-3-yl]-N-hydroxy-, (2E)-

(E)-3-[1-[[4-[(Dimethylamino)methyl]benzene]sulfonyl]-1H-pyrrol-3-yl]-N-hydroxyacrylamide Resminostat

(E)-3-(1-((4-((Dimethylamino)methyl)phenyl)sulfonyl)-1H-pyrrol-3-yl)-N-hydroxyacrylamide

4SC-201(resminostat,BYK408740)

864814-88-0

Inhibitor

Inhibitors