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AUDA

Product Name
AUDA
CAS No.
479413-70-2
Chemical Name
AUDA
Synonyms
AUDA;AUDA,≥98%;AUDA, 10 mM in DMSO;12-(3-adamantan-1-yl-ureido)dodecanoic acid;12-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]-dodecanoic acid;Dodecanoic acid, 12-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]-;Inhibitor,anti-inflammatory,epoxide,inhibit,hydrolase,sEH,activity,AUDA,soluble,Epoxide Hydrolase,VSMC
CBNumber
CB32590311
Molecular Formula
C23H40N2O3
Formula Weight
392.58
MOL File
479413-70-2.mol
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AUDA Property

Melting point:
114 °C(Solv: hexane (110-54-3))
Boiling point:
592.7±19.0 °C(Predicted)
Density 
1.09±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO: ≥10mg/mL at warmed to 60°C
form 
powder
pka
4.78±0.10(Predicted)
color 
white to beige
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

Precautionary statements

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0177
Product name
AUDA
Purity
≥98% (HPLC)
Packaging
10mg
Price
$70.7
Updated
2025/07/31
Sigma-Aldrich
Product number
SML0177
Product name
AUDA
Purity
≥98% (HPLC)
Packaging
50mg
Price
$391
Updated
2025/07/31
Cayman Chemical
Product number
10007927
Product name
AUDA
Purity
>98%
Packaging
5mg
Price
$31
Updated
2024/03/01
Cayman Chemical
Product number
10007927
Product name
AUDA
Purity
>98%
Packaging
10mg
Price
$49
Updated
2024/03/01
Cayman Chemical
Product number
10007927
Product name
AUDA
Purity
>98%
Packaging
50mg
Price
$230
Updated
2024/03/01
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AUDA Chemical Properties,Usage,Production

Uses

AUDA is an inhibitor of sEH and selective activator of PPARα.

Biological Activity

Inhibition of soluble epoxide hydrolase by AUDA inhibits the metabolism of epoxyeicosatrienoic acids (EETs) and protects end-organs against the damaging effects of salt-sensitive hypertension. AUDA also renders protection against myocardial ischemia-reperfusion injury and cerebral ischemia.', 'AUDA is a potent inhibitor of soluble epoxide hydrolase

in vivo

AUDA (i.p.; 10 mg/kg; 14 days) reduces TNF-α, MMP-9 and IL-1β expression levels[3].

Animal Model:Male (wild-type) C57BL/6 mice (age, 4-6 weeks; weight, 18-20 g)[3]
Dosage:10 mg/kg
Administration:i.p.; 14 days
Result:Reduced TNF-α, MMP-9 and IL-1β expression levels.

AUDA Preparation Products And Raw materials

Raw materials

Preparation Products

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AUDA Suppliers

Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4747
Advantage
58
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4720
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
8011
Advantage
55
Shanghai Han-Xiang Chemical Co., Ltd.
Tel
15971444841
Fax
18327183813
Email
amber@biochempartner.com
Country
China
ProdList
3061
Advantage
58
Jiangsu aikang biomedical research and development co., LTD
Tel
025-58859352 13155353615
Email
qzhang@aikonchem.com
Country
China
ProdList
15525
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Labnetwork lnc.
Tel
+86-27-50766799 +8618062016861
Email
contact@labnetwork.com
Country
China
ProdList
19987
Advantage
58
Henan Weituxi Chemical Technology Co., Ltd.
Tel
0371-63284658 18135795563
Fax
QQ:2885349392
Email
2885349392@qq.com
Country
China
ProdList
9990
Advantage
58

479413-70-2, AUDARelated Search:


  • 12-(3-adamantan-1-yl-ureido)dodecanoic acid
  • AUDA
  • 12-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]-dodecanoic acid
  • Dodecanoic acid, 12-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]-
  • Inhibitor,anti-inflammatory,epoxide,inhibit,hydrolase,sEH,activity,AUDA,soluble,Epoxide Hydrolase,VSMC
  • AUDA, 10 mM in DMSO
  • AUDA,≥98%
  • 479413-70-2
  • C23H40N2O3