ChemicalBook > CAS DataBase List > AUDA

AUDA

Product Name: AUDA
CAS No.: 479413-70-2
Chemical Name: AUDA
Synonyms: AUDA;AUDA,≥98%;AUDA, 10 mM in DMSO;12-(3-adamantan-1-yl-ureido)dodecanoic acid;12-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]-dodecanoic acid;Dodecanoic acid, 12-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]-;Inhibitor,anti-inflammatory,epoxide,inhibit,hydrolase,sEH,activity,AUDA,soluble,Epoxide Hydrolase,VSMC
CBNumber: CB32590311
Molecular Formula: C23H40N2O3
Formula Weight: 392.58
MOL File: 479413-70-2.mol

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AUDA Property

Melting point:: 114 °C(Solv: hexane (110-54-3))
Boiling point:: 592.7±19.0 °C(Predicted)
Density: 1.09±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMSO: ≥10mg/mL at warmed to 60°C
form: powder
pka: 4.78±0.10(Predicted)
color: white to beige

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H303May be harmfulif swallowed
Precautionary statements: P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0177
Product name: AUDA
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $70.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML0177
Product name: AUDA
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $391
Updated: 2025/07/31

Cayman Chemical

Product number: 10007927
Product name: AUDA
Purity: >98%
Packaging: 5mg
Price: $31
Updated: 2024/03/01

Cayman Chemical

Product number: 10007927
Product name: AUDA
Purity: >98%
Packaging: 10mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 10007927
Product name: AUDA
Purity: >98%
Packaging: 50mg
Price: $230
Updated: 2024/03/01

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AUDA Chemical Properties,Usage,Production

Uses

AUDA is an inhibitor of sEH and selective activator of PPARα.

Biological Activity

Inhibition of soluble epoxide hydrolase by AUDA inhibits the metabolism of epoxyeicosatrienoic acids (EETs) and protects end-organs against the damaging effects of salt-sensitive hypertension. AUDA also renders protection against myocardial ischemia-reperfusion injury and cerebral ischemia.', 'AUDA is a potent inhibitor of soluble epoxide hydrolase

in vivo

AUDA (i.p.; 10 mg/kg; 14 days) reduces TNF-α, MMP-9 and IL-1β expression levels^[3].

Animal Model:	Male (wild-type) C57BL/6 mice (age, 4-6 weeks; weight, 18-20 g)^[3]
Dosage:	10 mg/kg
Administration:	i.p.; 14 days
Result:	Reduced TNF-α, MMP-9 and IL-1β expression levels.

AUDA Preparation Products And Raw materials

Raw materials

Preparation Products

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AUDA Suppliers

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479413-70-2, AUDARelated Search:

phenyl-[3-(4-phenylphenyl)oxiran-2-yl]methanone

12-(3-adamantan-1-yl-ureido)dodecanoic acid

AUDA

12-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]-dodecanoic acid

Dodecanoic acid, 12-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]-

Inhibitor,anti-inflammatory,epoxide,inhibit,hydrolase,sEH,activity,AUDA,soluble,Epoxide Hydrolase,VSMC

AUDA, 10 mM in DMSO

AUDA,≥98%

479413-70-2

C23H40N2O3