ChemicalBook > CAS DataBase List > AUDA
AUDA
- Product Name
- AUDA
- CAS No.
- 479413-70-2
- Chemical Name
- AUDA
- Synonyms
- AUDA;AUDA,≥98%;AUDA, 10 mM in DMSO;12-(3-adamantan-1-yl-ureido)dodecanoic acid;12-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]-dodecanoic acid;Dodecanoic acid, 12-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]-;Inhibitor,anti-inflammatory,epoxide,inhibit,hydrolase,sEH,activity,AUDA,soluble,Epoxide Hydrolase,VSMC
- CBNumber
- CB32590311
- Molecular Formula
- C23H40N2O3
- Formula Weight
- 392.58
- MOL File
- 479413-70-2.mol
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AUDA Property
- Melting point:
- 114 °C(Solv: hexane (110-54-3))
- Boiling point:
- 592.7±19.0 °C(Predicted)
- Density
- 1.09±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMSO: ≥10mg/mL at warmed to 60°C
- form
- powder
- pka
- 4.78±0.10(Predicted)
- color
- white to beige
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML0177
- Product name
- AUDA
- Purity
- ≥98% (HPLC)
- Packaging
- 10mg
- Price
- $70.7
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- SML0177
- Product name
- AUDA
- Purity
- ≥98% (HPLC)
- Packaging
- 50mg
- Price
- $391
- Updated
- 2025/07/31
Cayman Chemical
- Product number
- 10007927
- Product name
- AUDA
- Purity
- >98%
- Packaging
- 5mg
- Price
- $31
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 10007927
- Product name
- AUDA
- Purity
- >98%
- Packaging
- 10mg
- Price
- $49
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 10007927
- Product name
- AUDA
- Purity
- >98%
- Packaging
- 50mg
- Price
- $230
- Updated
- 2024/03/01
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AUDA Chemical Properties,Usage,Production
Uses
AUDA is an inhibitor of sEH and selective activator of PPARα.
Biological Activity
Inhibition of soluble epoxide hydrolase by AUDA inhibits the metabolism of epoxyeicosatrienoic acids (EETs) and protects end-organs against the damaging effects of salt-sensitive hypertension. AUDA also renders protection against myocardial ischemia-reperfusion injury and cerebral ischemia.', 'AUDA is a potent inhibitor of soluble epoxide hydrolase
in vivo
AUDA (i.p.; 10 mg/kg; 14 days) reduces TNF-α, MMP-9 and IL-1β expression levels[3].
| Animal Model: | Male (wild-type) C57BL/6 mice (age, 4-6 weeks; weight, 18-20 g)[3] |
| Dosage: | 10 mg/kg |
| Administration: | i.p.; 14 days |
| Result: | Reduced TNF-α, MMP-9 and IL-1β expression levels. |
AUDA Preparation Products And Raw materials
Raw materials
Preparation Products
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AUDA Suppliers
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