BAY-41-8543

Product Name: BAY-41-8543
CAS No.: 256498-66-5
Chemical Name: BAY-41-8543
Synonyms: BAY-41-8543;BAY-41-8543 Exclusive;BAY 41-8543 (BAY 418543);2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]-5-morpholin-4-ylpyrimidine-4,6-diamine;2-[1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamine;4,6-Pyrimidinediamine, 2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-;BAY 418543,vascular,systemic,antiplatelet,vasodilator,soluble,pulmonary,orally,nitric,beds,cardiovascular,BAY 41 8543,Guanylate Cyclase,Inhibitor,sGC,BAY 41-8543,oxide,inhibit
CBNumber: CB32590331
Molecular Formula: C21H21FN8O
Formula Weight: 420.44
MOL File: 256498-66-5.mol

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BAY-41-8543 Property

Boiling point:: 599.7±50.0 °C(Predicted)
Density: 1.55±0.1 g/cm3(Predicted)
solubility: DMF: 3 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml
form: A crystalline solid
pka: 5.18±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2727
Product name: BAY 41-8543
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $123
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML2727
Product name: BAY 41-8543
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $495
Updated: 2024/03/01

Cayman Chemical

Product number: 10011131
Product name: BAY 41-8543
Purity: ≥98%
Packaging: 1mg
Price: $35
Updated: 2024/03/01

Cayman Chemical

Product number: 10011131
Product name: BAY 41-8543
Purity: ≥98%
Packaging: 5mg
Price: $114
Updated: 2024/03/01

Cayman Chemical

Product number: 10011131
Product name: BAY 41-8543
Purity: ≥98%
Packaging: 10mg
Price: $210
Updated: 2024/03/01

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BAY-41-8543 Chemical Properties,Usage,Production

Uses

BAY 41-8543, is a Guanylyl cyclase (sGC) stimulator, increasing the activity of recombinant sGC dose-dependently, from 0.1 nM to 100 μM, up to 92-fold. BAY 41-8543 reduces pulmonary vascular resistance and protects right ventricular (RV)function. It also inhibits collagen-induced platelet aggregation, and promotes lipid uptake into brown adipose tissue and increases energy expenditure in mice. It has also shown Antihypertensive activity.

Definition

ChEBI: BAY-41-8543 is a pyrazolopyridine.

storage

Store at -20°C

BAY-41-8543 Preparation Products And Raw materials

Raw materials

Preparation Products

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BAY-41-8543 Suppliers

China 33 United Kingdom 1 United States 8 USA 1 Global 43

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256498-66-5, BAY-41-8543Related Search:

BAY-41-8543

BAY-41-8543 Exclusive

BAY 41-8543 (BAY 418543)

2-[1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-4,6-pyrimidinediamine

4,6-Pyrimidinediamine, 2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-morpholinyl)-

BAY 418543,vascular,systemic,antiplatelet,vasodilator,soluble,pulmonary,orally,nitric,beds,cardiovascular,BAY 41 8543,Guanylate Cyclase,Inhibitor,sGC,BAY 41-8543,oxide,inhibit

2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]-5-morpholin-4-ylpyrimidine-4,6-diamine

256498-66-5

C21H21FN8O