(R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE

Product Name: (R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE
CAS No.: 22038-85-3
Chemical Name: (R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE
Synonyms: Einecs 244-747-2;[(R)-α-(Trifluoromethyl)benzyl]amine;2,2,2-trifluoro-1-phenylethan-1-aMine;[R,(-)]-α-(Trifluoromethyl)benzylamine;(R)-2,2,2-TRIFLUORO-1-PHENYLETHANAMINE;(R)-(-)-α-(trifluoromethyl)benzylamine;(R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE;(1R)-1-Phenyl-2,2,2-trifluoroethanamine;(1R)-2,2,2-trifluoro-1-phenylethanamine;(R)-2,2,2-Trifluoro-1-phenylethan-1-amine
CBNumber: CB3259047
Molecular Formula: C8H8F3N
Formula Weight: 175.15
MOL File: 22038-85-3.mol

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(R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE Property

Boiling point:: 196.4±40.0 °C(Predicted)
Density: 1.224±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
pka: 6.15±0.10(Predicted)
Appearance: White to off-white Solid

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Safety

Risk Statements: 34
Safety Statements: 26-36/37/39
RIDADR: 3259

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: T792748
Product name: (R)-2,2,2-Trifluoro-1-phenylethanamine
Packaging: 10mg
Price: $45
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3630-3-R6
Product name: (R)-2,2,2-Trifluoro-1-phenyl-ethylamine
Purity: 98%
Packaging: 250mg
Price: $205
Updated: 2021/12/16

AK Scientific

Product number: W4548
Product name: (R)-2,2,2-Trifluoro-1-phenylethanamine
Packaging: 1g
Price: $463
Updated: 2021/12/16

Matrix Scientific

Product number: 132417
Product name: (R)-2,2,2-Trifluoro-1-phenylethanamine
Purity: 97%
Packaging: 1g
Price: $478
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3630-3-R6
Product name: (R)-2,2,2-Trifluoro-1-phenyl-ethylamine
Purity: 98%
Packaging: 1g
Price: $505
Updated: 2021/12/16

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(R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE Chemical Properties,Usage,Production

Synthesis

51586-24-4

22038-85-3

General procedure for the synthesis of (R)-2,2,2-trifluoro-1-phenylethylamine from 1-phenyl-2,2,2-trifluoroethylamine: 1. Intermediate preparation: L-tartaric acid (36 g, 240.0 mmol) was added to a solution of 1-phenyl-2,2,2-trifluoroethylamine (40 g, 228.57 mmol) in isopropanol (400 mL). 2. Reaction: The reaction mixture was heated to reflux and maintained for 30 minutes. 3. Post-treatment: After completion of the reaction, the mixture was cooled to room temperature and the solid formed was collected by filtration. 4. Purification: The resulting solid was diluted with Na2CO3/H2O solution and subsequently extracted with dichloromethane (3 x 100 mL). 5. Drying and concentration: The organic phases were combined, dried over K2CO3 and subsequently concentrated under reduced pressure to afford the target product (1R)-2,2,2-trifluoro-1-phenylethylamine (12.5 g, 31% yield) as a white solid.

References

[1] Patent: WO2011/119701, 2011, A1. Location in patent: Page/Page column 40

(R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE Suppliers

China 56 France 1 Germany 2 India 3 Ukraine 1 United States 13 Global 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

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LABTER PHARMATECH(BEIJING) CO.,LTD

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22038-85-3, (R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINERelated Search:

4-(1-AZI-2,2,2-TRIFLUOROETHYL)BENZOIC ACID 2-METHOXY-4-[3-(TRIFLUOROMETHYL)-3H-DIAZIRIN-3-YL]BENZOIC ACID, METHYL ESTER (1R)-2,2,2-TRIFLUORO-1-(4-METHOXYPHENYL)ETHYLAMINE (1R)-1-(4-CHLOROPHENYL)-2,2,2-TRIFLUOROETHYLAMINE 1,6-BIS[3-(TRIFLUOROMETHYL)-3H-DIAZIRIN-3-YL]-3,8-DIMETHOXY-DIBENZENE 4-[3-(Trifluoromethyl)diazirin-3-yl]benzoic Acid N-Hydroxysuccinimide Ester 3-(3-METHOXYPHENYL)-3-(TRIFLUOROMETHYL)-DIAZIRIDINE 3-(3-METHOXYPHENYL)-3-(TRIFLUOROMETHYL)-3H-DIAZIRINE (R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE 2,2,2-TRIFLUORO-1-(4-METHOXY-PHENYL)-ETHYLAMINE 2-HYDROXY-4-[3-(TRIFLUOROMETHYL)-3H-DIAZIRIN-3-YL]BENZOIC ACID, METHYL ESTER 1-(4-BROMO-PHENYL)-2,2,2-TRIFLUORO-ETHYLAMINE HYDROBROMIDE 2-N-[4-(1-AZITRIFLUOROETHYL)BENZOYL]-1,3-BIS-(D-MANNOS-4-YLOXY)-2-PROPYLAMINE (S)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE 2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE HCL (R)-2,2,2-TRIFLUORO-1-(3-FLUORO-PHENYL)-ETHYLAMINE (1R)-2,2,2-TRIFLUORO-1-(4-PHENOXYPHENYL)ETHYLAMINE 3,3,3-TRIFLUORO-2-PHENYLALANINE

(R)-2,2,2-TRIFLUORO-1-PHENYLETHANAMINE

(R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE

(R)-(-)-alpha-(trifluoromethyl)benzylamine

(1R)-1-Phenyl-2,2,2-trifluoroethanamine

[(R)-α-(Trifluoromethyl)benzyl]amine

[R,(-)]-α-(Trifluoromethyl)benzylamine

Einecs 244-747-2

Benzenemethanamine, .alpha.-(trifluoromethyl)-, (.alpha.R)-

2,2,2-trifluoro-1-phenylethan-1-aMine

(R)-2,2,2-Trifluoro-1-phenylethan-1-amine

(1R)-2,2,2-trifluoro-1-phenylethanamine

(R)-(-)-α-(trifluoromethyl)benzylamine

Benzenemethanamine, α-(trifluoromethyl)-, (αR)-

22038-85-3