(R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE
- Product Name
- (R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE
- CAS No.
- 22038-85-3
- Chemical Name
- (R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE
- Synonyms
- Einecs 244-747-2;[(R)-α-(Trifluoromethyl)benzyl]amine;2,2,2-trifluoro-1-phenylethan-1-aMine;[R,(-)]-α-(Trifluoromethyl)benzylamine;(R)-2,2,2-TRIFLUORO-1-PHENYLETHANAMINE;(R)-(-)-α-(trifluoromethyl)benzylamine;(R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE;(1R)-1-Phenyl-2,2,2-trifluoroethanamine;(1R)-2,2,2-trifluoro-1-phenylethanamine;(R)-2,2,2-Trifluoro-1-phenylethan-1-amine
- CBNumber
- CB3259047
- Molecular Formula
- C8H8F3N
- Formula Weight
- 175.15
- MOL File
- 22038-85-3.mol
(R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE Property
- Boiling point:
- 196.4±40.0 °C(Predicted)
- Density
- 1.224±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 6.15±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39
- RIDADR
- 3259
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T792748
- Product name
- (R)-2,2,2-Trifluoro-1-phenylethanamine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 3630-3-R6
- Product name
- (R)-2,2,2-Trifluoro-1-phenyl-ethylamine
- Purity
- 98%
- Packaging
- 250mg
- Price
- $205
- Updated
- 2021/12/16
- Product number
- W4548
- Product name
- (R)-2,2,2-Trifluoro-1-phenylethanamine
- Packaging
- 1g
- Price
- $463
- Updated
- 2021/12/16
- Product number
- 132417
- Product name
- (R)-2,2,2-Trifluoro-1-phenylethanamine
- Purity
- 97%
- Packaging
- 1g
- Price
- $478
- Updated
- 2021/12/16
- Product number
- 3630-3-R6
- Product name
- (R)-2,2,2-Trifluoro-1-phenyl-ethylamine
- Purity
- 98%
- Packaging
- 1g
- Price
- $505
- Updated
- 2021/12/16
(R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE Chemical Properties,Usage,Production
Synthesis
51586-24-4
22038-85-3
General procedure for the synthesis of (R)-2,2,2-trifluoro-1-phenylethylamine from 1-phenyl-2,2,2-trifluoroethylamine: 1. Intermediate preparation: L-tartaric acid (36 g, 240.0 mmol) was added to a solution of 1-phenyl-2,2,2-trifluoroethylamine (40 g, 228.57 mmol) in isopropanol (400 mL). 2. Reaction: The reaction mixture was heated to reflux and maintained for 30 minutes. 3. Post-treatment: After completion of the reaction, the mixture was cooled to room temperature and the solid formed was collected by filtration. 4. Purification: The resulting solid was diluted with Na2CO3/H2O solution and subsequently extracted with dichloromethane (3 x 100 mL). 5. Drying and concentration: The organic phases were combined, dried over K2CO3 and subsequently concentrated under reduced pressure to afford the target product (1R)-2,2,2-trifluoro-1-phenylethylamine (12.5 g, 31% yield) as a white solid.
References
[1] Patent: WO2011/119701, 2011, A1. Location in patent: Page/Page column 40
(R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
(R)-2,2,2-TRIFLUORO-1-PHENYL-ETHYLAMINE Suppliers
- Tel
- --
- Fax
- --
- mark.witterholt@minakem.com
- Country
- France
- ProdList
- 200
- Advantage
- 30